Inter-Protein Sequence Co-Evolution Predicts Known Physical Interactions in Bacterial Ribosomes and the Trp Operon. [PDF]
PLoS ONE, 2016 Interaction between proteins is a fundamental mechanism that underlies virtually all biological processes. Many important interactions are conserved across a large variety of species.
Christoph Feinauer +3 more
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The Bacillus subtilis TRAP protein can induce transcription termination in the leader region of the tryptophan biosynthetic (trp) operon independent of the trp attenuator RNA. [PDF]
PLoS ONE, 2014 In Bacillus subtilis, transcription of the tryptophan biosynthetic operon is regulated by an attenuation mechanism. When intracellular tryptophan levels are high, the TRAP protein binds to the 5' leader region of the nascent trp mRNA and induces ...
Natalie M McAdams, Paul Gollnick
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Positions of Trp codons in the leader peptide-coding region of the at operon influence anti-trap synthesis and trp operon expression in Bacillus licheniformis. [PDF]
J Bacteriol, 2010 ABSTRACT Tryptophan, phenylalanine, tyrosine, and several other metabolites are all synthesized from a common precursor, chorismic acid. Since tryptophan is a product of an energetically expensive biosynthetic pathway, bacteria have developed sensing mechanisms to downregulate synthesis of the enzymes of tryptophan formation when
Levitin A, Yanofsky C.
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ALE reveals a surprising link between [Fe-S] cluster formation, tryptophan biosynthesis and the potential regulatory protein TrpP in Corynebacterium glutamicum [PDF]
BMC MicrobiologyBackground The establishment of synthetic microbial communities comprising complementary auxotrophic strains requires efficient transport processes for common goods. With external supplementation of the required metabolite, most auxotrophic strains reach
Rico Zuchowski +7 more
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Modelling the evolution of the archaeal tryptophan synthase [PDF]
BMC Evolutionary Biology, 2007 Background Microorganisms and plants are able to produce tryptophan. Enzymes catalysing the last seven steps of tryptophan biosynthesis are encoded in the canonical trp operon.
Merkl Rainer
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Modular Organization of the NusA- and NusG-Stimulated RNA Polymerase Pause Signal That Participates in the Bacillus subtilis trp Operon Attenuation Mechanism. [PDF]
J Bacteriol, 2017 Mondal S, Yakhnin AV, Babitzke P.
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Modulating TRAP-mediated transcription termination by AT during transcription of the leader region of the Bacillus subtilis trp operon. [PDF]
Nucleic Acids Res, 2014 Sharma S, Gollnick P.
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Molecular basis of TRAP-5'SL RNA interaction in the Bacillus subtilis trp operon transcription attenuation mechanism. [PDF]
RNA, 2009 McGraw AP +4 more
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Biomedical and Biotechnology Research Journal, 2022 Background: The repeating elements in the genes or genomes of living organisms are associated with a variety of functions at the molecular level. Mirror repeats (MRs) are unique type of repeat sequences among them, which are found to be linked with H-DNA
Sandeep Yadav +2 more
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The rate of TRAP binding to RNA is crucial for transcription attenuation control of the B. subtilis trp operon. [PDF]
J Mol Biol, 2007 Barbolina MV +4 more
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