Results 11 to 20 of about 16,282 (199)
Physiological effects of anti-TRAP protein activity and tRNA(Trp) charging on trp operon expression in Bacillus subtilis. [PDF]
J Bacteriol, 2008 ABSTRACT The Bacillus subtilis anti-TRAP protein regulates the ability of the tryptophan-activated TRAP protein to bind to trp operon leader RNA and promote transcription termination.
Cruz-Vera LR, Gong M, Yanofsky C.
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TRP and Rhodopsin Transport Depends on Dual XPORT ER Chaperones Encoded by an Operon [PDF]
Cell Reports, 2015 TRP channels and G protein-coupled receptors (GPCRs) play critical roles in sensory reception. However, the identities of the chaperones that assist GPCRs in translocating from the endoplasmic reticulum (ER) are limited, and TRP ER chaperones are ...
Zijing Chen +2 more
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Detection of transcription-pausing in vivo in the trp operon leader region. [PDF]
Proceedings of the National Academy of Sciences, 1987 To determine whether RNA polymerase pauses during transcription in vivo, we have examined transcripts of the trp operon leader regions of Serratia marcescens and Escherichia coli. Labeled RNAs synthesized in E. coli strains containing plasmids bearing wild-type or mutant trp leader regions of S. marcescens or E.
Robert Landick +2 more
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Evolution of bacterial trp operons and their regulation [PDF]
Current Opinion in Microbiology, 2008 Survival and replication of most bacteria require the ability to synthesize the amino acid L-tryptophan whenever it is not available from the environment. In this article we describe the genes, operons, proteins, and reactions involved in tryptophan biosynthesis in bacteria, and the mechanisms they use in regulating tryptophan formation.
Enrique Merino +2 more
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tRNATrp as a key element of antitermination in the Lactococcus lactis trp operon [PDF]
Molecular Microbiology, 1998 The expression of the trp operon of Lactococcus lactis is regulated in response to tryptophan availability by a mechanism of transcription antitermination. We present evidence in support of a previously described model involving tRNATrp as a key element in the sensing of tryptophan levels and the realization of the regulatory response to tryptophan ...
Maarten van de Guchte +2 more
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Regulation of the Bacillus subtilis trp operon by an RNA‐binding protein [PDF]
Molecular Microbiology, 1994 SummaryThe Bacillus subtilis tryptophan (trpEDCFBA) operon is regulated by transcription attenuation. Transcription is controlled by two alternative RNA secondary structures, which form in the leader transcript. In the presence of L‐tryptophan, a transcription terminator forms and the operon is not expressed, whereas in the absence of tryptophan, an ...
Paul Gollnick
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Identification and Characterization of a Novel d-Branched-Chain Amino Acids Importer from Lactobacillus fermentum. [PDF]
ChembiochemCertain lactic acid bacteria produce d‐branched‐chain amino acids (d‐BCAA) and encode isoleucine 2‐epimerase (ILEP) and an uncharacterized transporter (AAP). We demonstrate that the transporter is a novel, non‐stereospecific BCAA importer. The ILEP‐AAP operon likely aids in storing and utilizing BCAA in a form less accessible to other organisms ...
Aoki K +4 more
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Dynamic Quaternary Associations in Regulating Expression of the B. Subtilis Trp Operon [PDF]
Biophysical Journal, 2017 A large proportion of regulatory proteins are homo-oligomeric, with multiple copies of the same polypeptide assembled into higher-order quaternary structures. In addition to a capacity for both homotropic and heterotropic allostery, homo-oligomeric structures are capable of polyvalent interactions with multiple binding partners, such that different ...
Mark P. Foster
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Journal of Biological Chemistry, 1984 We have examined the leader transcript of the Serratia marcescens trp operon to determine if the alternate secondary structures postulated to control transcription attenuation actually form in purified trp leader RNA. RNA secondary structures were analyzed by partial digestion of 32P end-labeled leader transcripts with single and double strand-specific
Mitzi I. Kuroda, Charles Yanofsky
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In Vitro Repression of Transcription of the Trytophan Operon by trp Repressor [PDF]
Proceedings of the National Academy of Sciences, 1973 The in vitro repression of transcription of the tryptophan operon by the trp repressor from Escherichia coli was studied. By measuring the inhibitory effect for trp -specific RNA synthesis in an in vitro transcription ...
Yoshiko Shimizu +2 more
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