Results 11 to 20 of about 16,700 (189)

Artificial citrate operon confers mineral phosphate solubilization ability to diverse fluorescent pseudomonads. [PDF]

PLoS ONE, 2014
Citric acid is a strong acid with good cation chelating ability and can be very efficient in solubilizing mineral phosphates. Only a few phosphate solubilizing bacteria and fungi are known to secrete citric acids. In this work, we incorporated artificial
Hemanta Adhikary, Paulomi B Sanghavi, Silviya R Macwan, Gattupalli Archana, G Naresh Kumar   +4 more
doaj   +1 more source

Allosteric regulation of substrate channeling: Salmonella typhimurium tryptophan synthase

Frontiers in Molecular Biosciences, 2022
The regulation of the synthesis of L-tryptophan (L-Trp) in enteric bacteria begins at the level of gene expression where the cellular concentration of L-Trp tightly controls expression of the five enzymes of the Trp operon responsible for the synthesis ...
Rittik K. Ghosh, Eduardo Hilario, Chia-en A. Chang, Leonard J. Mueller, Michael F. Dunn   +4 more
doaj   +1 more source

Comprehensive Genomic Characterization of Staphylococcus aureus Isolated from Atopic Dermatitis Patients in Japan: Correlations with Disease Severity, Eruption Type, and Anatomical Site

Microbiology Spectrum, 2023
Atopic dermatitis (AD) shows frequent recurrence. Staphylococcus aureus is the primary microbial component in AD and is associated with disease activity.
Shoko Obata, Junzo Hisatsune, Hiroshi Kawasaki, Ayano Fukushima-Nomura, Tamotsu Ebihara, Chika Arai, Kanako Masuda, Shoko Kutsuno, Yasuhisa Iwao, Motoyuki Sugai, Masayuki Amagai, Keiji Tanese   +11 more
doaj   +1 more source

The iron-dependent repressor YtgR is a tryptophan-dependent attenuator of the trpRBA operon in Chlamydia trachomatis

Nature Communications, 2020
Chlamydia trachomatis does not possess TrpL-mediated transcription attenuation of its trp operon. Here, the authors show that an iron-dependent regulator, YtgR, acts as a tryptophan-dependent attenuator of the trp operon in this organism, due to ...
Nick D. Pokorzynski, Nathan D. Hatch, Scot P. Ouellette, Rey A. Carabeo   +3 more
doaj   +1 more source

Chlamydia suis displays high transformation capacity with complete cloning vector integration into the chromosomal rrn-nqrF plasticity zone

Microbiology Spectrum, 2023
Chlamydia, comprising several human and zoonotic pathogens, is a genus of the conserved bacterial phylum Chlamydiota. Their obligate intracellular niche serves as a barrier for natural genetic exchange via horizontal gene transfer (HGT), and further ...
Hanna Marti, Michael Biggel, Kensuke Shima, Delia Onorini, Jan Rupp, Steve J. Charette, Nicole Borel   +6 more
doaj   +1 more source

Dissecting the role of critical residues and substrate preference of a Fatty Acyl-CoA Synthetase (FadD13) of Mycobacterium tuberculosis. [PDF]

PLoS ONE, 2009
Newly emerging multi-drug resistant strains of Mycobacterium tuberculosis (M.tb) severely limit the treatment options for tuberculosis (TB); hence, new antitubercular drugs are urgently needed.
Garima Khare, Vibha Gupta, Rakesh K Gupta, Radhika Gupta, Rajiv Bhat, Anil K Tyagi   +5 more
doaj   +1 more source

What makes ribosome-mediated transcriptional attenuation sensitive to amino acid limitation?

PLoS Computational Biology, 2005
Ribosome-mediated transcriptional attenuation mechanisms are commonly used to control amino acid biosynthetic operons in bacteria. The mRNA leader of such an operon contains an open reading frame with "regulatory" codons, cognate to the amino acid that ...
Johan Elf, Måns Ehrenberg
doaj   +2 more sources

Modelling the evolution of the archaeal tryptophan synthase

BMC Evolutionary Biology, 2007
Background Microorganisms and plants are able to produce tryptophan. Enzymes catalysing the last seven steps of tryptophan biosynthesis are encoded in the canonical trp operon.
Merkl Rainer
doaj   +1 more source

Clinical Persistence of Chlamydia trachomatis Sexually Transmitted Strains Involves Novel Mutations in the Functional αββα Tetramer of the Tryptophan Synthase Operon. [PDF]

, 2019
Clinical persistence of Chlamydia trachomatis (Ct) sexually transmitted infections (STIs) is a major public health concern. In vitro persistence is known to develop through interferon gamma (IFN-γ) induction of indoleamine 2,3-dioxygenase (IDO), which ...
Dean, Deborah, Ferrin, Thomas E, Hyuk Suh, Jung, Somboonna, Naraporn, Ziklo, Noa   +4 more
core   +1 more source

The TK0271 Protein Activates Transcription of Aromatic Amino Acid Biosynthesis Genes in the Hyperthermophilic Archaeon Thermococcus kodakarensis

mBio, 2019
TrpY from Methanothermobacter thermautotrophicus is a regulator that inhibits transcription of the Trp biosynthesis (trp) operon. Here, we show that the TrpY homolog in Thermococcus kodakarensis is not involved in such regulation.
Yasuyuki Yamamoto, Tamotsu Kanai, Tsuyoshi Kaneseki, Haruyuki Atomi   +3 more
doaj   +1 more source