A Unique Tryptophan C‐Prenyltransferase from the Kawaguchipeptin Biosynthetic Pathway [PDF]
, 2016 Acknowledgements This work was supported by funding of the Academy of Finland (259505), Helsinki University Research grant (490085) and ESCMID grant (4720572) to D.P.F., University of Pittsburgh Central Research Development Fund to X.L., Technology ...
Arnison +21 more
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The Streptomyces coelicolor small ORF trpM stimulates growth and morphological development and exerts opposite effects on actinorhodin and calcium-dependent antibiotic production [PDF]
, 2020 In actinomycetes, antibiotic production is often associated with a morpho-physiological differentiation program that is regulated by complex molecular and metabolic networks. Many aspects of these regulatory circuits have been already elucidated and many
Alberto Vassallo +7 more
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Comparative analysis of RNA regulatory elements of amino acid metabolism genes in Actinobacteria
BMC Microbiology, 2005 Background Formation of alternative structures in mRNA in response to external stimuli, either direct or mediated by proteins or other RNAs, is a major mechanism of regulation of gene expression in bacteria.
Gelfand Mikhail S +3 more
doaj +1 more source
Effect of Tryptophan Analogs on Derepression of the \u3cem\u3eEscherichia coli\u3c/em\u3e Tryptophan Operon by Indole-3-Propionic Acid [PDF]
, 1978 The abilities of 14 tryptophan analogs to repress the tryptophan (trp) operon have been studied in Escherichia coli cells derepressed by incubation with 0.25 mM indole-3-propionic acid (IPA).
Fredricks, Walter W. +2 more
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TagF-mediated repression of bacterial type VI secretion systems involves a direct interaction with the cytoplasmic protein Fha [PDF]
, 2018 The bacterial type VI secretion system (T6SS) delivers effectors into eukaryotic host cells or toxins into bacterial competitor for survival and fitness.
Filloux, A +5 more
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, 2016 Understanding protein-protein interactions is central to our understanding of almost all complex biological processes. Computational tools exploiting rapidly growing genomic databases to characterize protein-protein interactions are urgently needed. Such
Baldassi, Carlo +4 more
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MicrobiologyOpen, Volume 14, Issue 6, December 2025.The novel Paenibacillus sp. strain 210, isolated from Brazilian crude oil, its genome encoding 259 carbohydrate‐active enzymes for degrading cellulose, xylan, and pectin, positioning it as a candidate for biofuel production. The strain harbors complete pathways for B‐vitamin biosynthesis and antimicrobial biosynthetic clusters (e.g., fusaricidin and ...
João Victor dos Anjos Almeida +5 more
wiley +1 more source
An ABC transporter containing a forkhead-associated domain interacts with a serine-threonine protein kinase and is required for growth of Mycobacterium tuberculosis in mice [PDF]
, 2005 Forkhead-associated (FHA) domains are modular phosphopeptide recognition motifs with a striking preference for phosphothreonine-containing epitopes. FHA domains have been best characterized in eukaryotic signaling pathways but have been identified in six
Buxton, RS +8 more
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In Vivo Biosynthesis and Direct Incorporation of Noncanonical Amino Acids into Proteins
ChemBioChem, Volume 26, Issue 22, November 17, 2025.This review evaluates engineered (semi)autonomous cell systems for the biosynthesis and incorporation of noncanonical amino acids (ncAAs) into proteins. While semi‐autonomous cells convert supplied precursors into ncAAs autonomous cells integrate biosynthetic pathways that produce these building blocks intracellularly.
Jan Hendrik Illies +2 more
wiley +1 more source
Validation of a model of regulation in the tryptophan operon against multiple experiment data using global optimisation [PDF]
, 2009 This paper is concerned with validating a mathematical model of regulation in the tryptophan operon using global optimization. Although a number of models for this biochemical network are proposed, in many cases only qualitative agreement between the ...
Bates, D.G. +4 more
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