Results 41 to 50 of about 16,700 (189)

Origin and characterization of cyclodepsipeptides: Comprehensive structural approaches with focus on mass spectrometry analysis of alkali‐cationized molecular species

Mass Spectrometry Reviews, Volume 44, Issue 6, Page 1013-1098, November/December 2025.
Abstract Cyclodepsipeptides (CDPs) represent a huge family of chemically and structurally diverse molecules with a wide ability for molecular interactions. CDPs are cyclic peptide‐related natural products made up of both proteinogenic and nonproteinogenic amino acids linked by amide and ester bonds.
Sophie Liuu, Annelaure Damont, Alain Perret, Olivier Firmesse, François Becher, Gwenaëlle Lavison‐Bompard, Amandine Hueber, Amina S. Woods, Ekaterina Darii, François Fenaille, Jean‐Claude Tabet   +10 more
wiley   +1 more source

Cosmid Cloning of Five \u3cem\u3eZymomonas trp\u3c/em\u3e Genes by Complementation of \u3cem\u3eEscherichia coli\u3c/em\u3e and \u3cem\u3ePseudomonas putida trp\u3c/em\u3e Mutants [PDF]

, 1988
A library of Zymomonas mobilis genomic DNA was constructed in the broad-host-range cosmid pLAFR1. The library was mobilized into a variety of Escherichia coli and Pseudomonas putida trp mutants by using the helper plasmid pRK2013. Five Z.
Eddy, Christina Kay, Noel, K. Dale, Smith, Oliver H.   +2 more
core   +1 more source

Evolution of substrate specificity in a recipient's enzyme following horizontal gene transfer [PDF]

, 2013
Despite the prominent role of horizontal gene transfer (HGT) in shaping bacterial metabolism, little is known about the impact of HGT on the evolution of enzyme function.
Abascal, Aldo R. Camacho-Zarco, Barona-Gomez, Brune, Carver, Collaborative Computational Project, Number 4 (CCP4), Dean, Depristo, Des Marais, Dittmar, Due, Francisco Barona-Gómez, Glykos, Guindon, Henn-Sax, Hess, Hodgson, Hu, Hughes, Humphrey, Ikeda, James, Jensen, Jensen, Jones, Jorgensen, Jung, Kane, Klassen, Kuper, Leaver-Fay, Lerat, Lianet Noda-García, MacKerell, Mauricio Carrillo-Tripp, McCoy, Murshudov, Nester, Noda-Garcia, Ohno, Pal, Parish, Paul Gaytán, Perrakis, Piatigorsky, Sofía Medina-Ruíz, Sterner, Tokuriki, Tokuriki, Treangen, Vilmos Fülöp, Vriend, Wright, Xie, Xie   +54 more
core   +1 more source

Solution structure, dynamics and tetrahedral assembly of Anti-TRAP, a homo-trimeric triskelion-shaped regulator of tryptophan biosynthesis in Bacillus subtilis

Journal of Structural Biology: X
Cellular production of tryptophan is metabolically expensive and tightly regulated. The small Bacillus subtilis zinc binding Anti-TRAP protein (AT), which is the product of the yczA/rtpA gene, is upregulated in response to accumulating levels of ...
Craig A. McElroy, Elihu C. Ihms, Deepak Kumar Yadav, Melody L. Holmquist, Vibhuti Wadhwa, Vicki H. Wysocki, Paul Gollnick, Mark P. Foster   +7 more
doaj   +1 more source

Sphingosine Phosphate Lyase Expression Is Essential for Normal Development in Caenorhabditis elegans [PDF]

, 2003
Sphingolipids are ubiquitous membrane constituents whose metabolites function as signaling molecules in eukaryotic cells. Sphingosine 1-phosphate, a key sphingolipid second messenger, regulates proliferation, motility, invasiveness, and programmed cell ...
Fyrst, Henrik, Heinecke, Karie, Mendel, Jane, Saba, Julie D.   +3 more
core   +1 more source

Condition‐dependent resource allocation strategy governed by CodY regulator in Bacillus subtilis

mLife, Volume 4, Issue 5, Page 539-550, October 2025.
Abstract To thrive in nature, bacteria have to rapidly proliferate in favorable conditions while constantly adapt to the fluctuating nutrient environments. However, the molecular players that ensure rapid growth of bacteria in favorable conditions remain poorly understood.
Haoyan Mu, Yiheng Wang, Yongfu Pei, Xin Wang, Xiongfeng Dai, Manlu Zhu   +5 more
wiley   +1 more source

The toxic effects of meta‐tyrosine are related to its misincorporation into the proteome and to altered metabolism in cyanobacteria

The FEBS Journal, Volume 292, Issue 20, Page 5439-5456, October 2025.
This study reveals that meta‐tyrosine (m‐Tyr), a nonproteinogenic analog of aromatic amino acids, disrupts protein synthesis and photosynthesis in cyanobacteria by being misincorporated by Phenylalanyl‐tRNA synthetase (PheRS) into essential proteins. Through molecular, biochemical, and proteomic analyses in Synechocystis, the research shows that m‐Tyr ...
Hagit Zer, Roei Matan, David Rasin, Yoram Soroka, Noa Carmi, Hanan Schoffman, Nir Keren, Jörg Nickelsen, Oren Ostersetzer‐Biran   +8 more
wiley   +1 more source

Studies of the membrane‐bound flavocytochrome MsrQ flavin mononucleotide (FMN)‐binding site reveal an unexpected ubiquinone cofactor

The FEBS Journal, Volume 292, Issue 20, Page 5491-5505, October 2025.
The membrane‐bound heme flavoprotein MsrQ is the specific electron donor for the periplasmic methionine sulfoxide reductase MsrP. Analysis of its flavin environment revealed that ubiquinone (UQ) is a cofactor for MsrQ. However, redox studies demonstrate that UQ cannot function as an electron donor for the MsrPQ system.
Philippe Carpentier, Fabien Pierrel, Nicolas Duraffourg, Bruno Guigliarelli, Mahmoud Hajj Chehade, Laura Flandrin, Christian Basset, Christelle Caux, Stéphane Torelli, Vincent Nivière   +9 more
wiley   +1 more source

An open reading frame upstream from the nifH gene of Klebsiella pneumoniae [PDF]

, 1983
An open reading frame upstream from nifHDK operon of Klebsiella pneumoniae had been described. The orientation of this open reading frame is opposite to that of nifHDK and sequence homology was found between the open reading frame promoter and the ...
Kong, Qiu-tong, Shen, San-chiun, Wu, Qi-long, Xue, Zhong-tian   +3 more
core  

Genome-Wide Study of mRNA Degradation and Transcript Elongation in Escherichia coli [PDF]

, 2015
An essential part of gene expression is the coordination of RNA synthesis and degradation, which occurs in the same cellular compartment in bacteria.
Chen, Huiyi, Ge, Hao, Shiroguchi, Katsuyuki, Xie, Xiaoliang Sunney   +3 more
core   +2 more sources