Results 51 to 60 of about 16,282 (199)

Single base-pair alterations in the Escherichia coli trp operon leader region that relieve transcription termination at the trp attenuator. [PDF]

Proceedings of the National Academy of Sciences, 1978
We have isolated a set of regulatory mutants defective in transcription termination at the attenuator in the leader region of the Escherichia coli tryptophan (trp) operon. In vivo the mutants have 2- to 4-fold increased levels of expression of the trp operon above the level of the trpR parental strain. These levels are increased an additional 1.5- to 2-
George V. Stauffer, Gérard Zurawski, Charles Yanofsky   +2 more
openalex   +4 more sources

Direct selection and analysis of mutational events which diminish the level of expression of the trp operon [PDF]

Journal of Bacteriology, 1980
A new procedure was devised for selecting, from lac+ galE strains of Escherichia coli, mutants resistant to galactoside-induced lysis. When applied to trp-lac fusions, our method yields down mutations in the trp promoter.
James C. Andrews, Ronald L. Somerville
openalex   +4 more sources

Comparative analysis of RNA regulatory elements of amino acid metabolism genes in Actinobacteria

BMC Microbiology, 2005
Background Formation of alternative structures in mRNA in response to external stimuli, either direct or mediated by proteins or other RNAs, is a major mechanism of regulation of gene expression in bacteria.
Gelfand Mikhail S, Putzer Harald, Seliverstov Alexander V, Lyubetsky Vassily A   +3 more
doaj   +1 more source

Metabolite-dependent regulation of gene expression in trypanosoma brucei [PDF]

, 2013
Mechanisms regulating gene expression in trypanosomatid protozoa differ significantly from those in other eukaryotes. Transcription of the genome appears to be more or less constitutive with the polyadenylation and trans-splicing of large polycistronic ...
Archer, Batey, Besteiro, Birkholtz, Breaker, Carter, Clayton, Coustou, De Gaudenzi, Ebikeme, Fairlamb, Hendriks, Jacob, Jensen, Kabani, Lamour, Mangold, Martinez-Calvillo, Nguyen, Perez-Leal, Persson, Phillips, Stuart, Veitch, Vincent, Ward, Willert, Willert, Willert, Wirtz, Wurst, Wurst, Xiao, Xiao, Zhang   +34 more
core   +1 more source

Effect of Tryptophan Analogs on Derepression of the \u3cem\u3eEscherichia coli\u3c/em\u3e Tryptophan Operon by Indole-3-Propionic Acid [PDF]

, 1978
The abilities of 14 tryptophan analogs to repress the tryptophan (trp) operon have been studied in Escherichia coli cells derepressed by incubation with 0.25 mM indole-3-propionic acid (IPA).
Fredricks, Walter W., Pauley, Robert J., Smith, Oliver H.   +2 more
core   +1 more source

Origin and characterization of cyclodepsipeptides: Comprehensive structural approaches with focus on mass spectrometry analysis of alkali‐cationized molecular species

Mass Spectrometry Reviews, EarlyView.
Abstract Cyclodepsipeptides (CDPs) represent a huge family of chemically and structurally diverse molecules with a wide ability for molecular interactions. CDPs are cyclic peptide‐related natural products made up of both proteinogenic and nonproteinogenic amino acids linked by amide and ester bonds.
Sophie Liuu, Annelaure Damont, Alain Perret, Olivier Firmesse, François Becher, Gwenaëlle Lavison‐Bompard, Amandine Hueber, Amina S. Woods, Ekaterina Darii, François Fenaille, Jean‐Claude Tabet   +10 more
wiley   +1 more source

Controlled overproduction of proteins by lactic acid bacteria [PDF]

, 1997
Lactic acid bacteria are widely used in industrial food fermentations, contributing to flavour, texture and preservation of the fermented products. Here we describe recent advances in the development of controlled gene expression systems, which allow the
Kleerebezem, Michiel,, Kuipers, Oscar P.,, Ruyter, Pascalle G.G.A. de,, Vos, Willem M. de,   +3 more
core   +3 more sources

First‐in‐class inhibitors of SbnA reduce siderophore production in Staphylococcus aureus

The FEBS Journal, EarlyView.
The production of the iron‐chelating compound staphyloferrin B by the most invasive S. aureus strains is crucial for colonization, virulence, and survival in the host. Staphyloferrin B biosynthesis is carried out by eight enzymes, the Sbn system, that offer an appealing source of potential targets for the development of antimicrobials.
Sarah Hijazi, Monica Cozzi, Somayeh Asgharpour, Omar De Bei, Serena Faggiano, Francesco Marchesani, Luca Ronda, Marialaura Marchetti, Eleonora Gianquinto, Mariacristina Failla, Gauthier Trèves, Loretta Lazzarato, Francesca Spyrakis, Barbara Campanini, Emanuela Frangipani, Stefano Bettati   +15 more
wiley   +1 more source

Germinant receptor diversity and germination responses of four strains of the Bacillus cereus group [PDF]

, 2010
Four strains of the Bacillus cereus group were compared for their germinant receptor composition and spore germination capacity. Phylogenetic analysis of the germinant receptor encoding operons of the enterotoxic strains B.
Abee, T., Garcia, D., Moezelaar, R., Voort, M., van der   +3 more
core   +2 more sources

The toxic effects of meta‐tyrosine are related to its misincorporation into the proteome and to altered metabolism in cyanobacteria

The FEBS Journal, EarlyView.
This study reveals that meta‐tyrosine (m‐Tyr), a nonproteinogenic analog of aromatic amino acids, disrupts protein synthesis and photosynthesis in cyanobacteria by being misincorporated by Phenylalanyl‐tRNA synthetase (PheRS) into essential proteins. Through molecular, biochemical, and proteomic analyses in Synechocystis, the research shows that m‐Tyr ...
Hagit Zer, Roei Matan, David Rasin, Yoram Soroka, Noa Carmi, Hanan Schoffman, Nir Keren, Jörg Nickelsen, Oren Ostersetzer‐Biran   +8 more
wiley   +1 more source