Results 21 to 30 of about 41,565 (180)
Contribution of calcium-conducting channels to the transport of zinc ions. [PDF]
, 2013 International audienceZinc (Zn) is a vital nutrient participating in a myriad of biological processes. The mechanisms controlling its transport through the plasma membrane are far from being completely understood.
Bouron, Alexandre, Oberwinkler, Johannes
core +4 more sources
TRP Channels: Current Perspectives in the Adverse Cardiac Remodeling [PDF]
, 2019 Calcium is an important second messenger required not only for the excitation-contraction coupling of the heart but also critical for the activation of cell signaling pathways involved in the adverse cardiac remodeling and consequently for the heart ...
Calderón Sánchez, Eva María +7 more
core +1 more source
Inward calcium current through the polycystin-2-dependent channels of renal primary cilia.
AJP - Renal Physiology, 2021 In 15% of cases, autosomal dominant polycystic kidney disease (ADPKD) arises from defects in polycystin-2 (PC2). PC2 is a member of the TRPP subfamily of cation-conducting channels and is expressed in the endoplasmic reticulum and primary cilium of renal
S. J. Kleene, Nancy K. Kleene
semanticscholar +1 more source
Structure of the full-length TRPV2 channel by cryo-EM. [PDF]
, 2016 Transient receptor potential (TRP) proteins form a superfamily Ca(2+)-permeable cation channels regulated by a range of chemical and physical stimuli. Structural analysis of a 'minimal' TRP vanilloid subtype 1 (TRPV1) elucidated a mechanism of channel ...
Cohen, Matthew R +6 more
core +2 more sources
Transient Receptor Potential channels (TRP) in GtoPdb v.2022.1
IUPHAR/BPS Guide to Pharmacology CITE, 2022 The TRP superfamily of channels (nomenclature as agreed by NC-IUPHAR [159, 999]), whose founder member is the Drosophila Trp channel, exists in mammals as six families; TRPC, TRPM, TRPV, TRPA, TRPP and TRPML based on amino acid homologies.
Nathaniel T. Blair +29 more
semanticscholar +1 more source
The role of TRP proteins in mast cells
Frontiers in Immunology, 2012 TRP proteins form cation channels that are regulated through strikingly diverse mechanisms including multiple cell surface receptors, changes in temperature, in pH and osmolarity, in cytosolic Ca2+ concentration ([Ca2+]i) and by phosphoinositides. The 28
Marc eFreichel +2 more
doaj +1 more source
What do we know about the transient receptor potential vanilloid 2 (TRPV2) ion channel? [PDF]
, 2013 Transient receptor potential (TRP) ion channels are emerging as a new set of membrane proteins involved in a vast array of cellular processes and regulated by a large number of physical and chemical stimuli, which involves them with sensory cell ...
Doñate-Macian, Pau +2 more
core +1 more source
Editorial: Emerging Roles of TRP Channels in Brain Pathology
Frontiers in Cell and Developmental Biology, 2021 The mammalian transient receptor potential (TRP) ion channel superfamily comprises six subfamilies, TRPC (canonical), TRPV (vanilloid), TRPM (melastatin), TRPA (ankyrin), TRPP (polycystin), and TRPML (mucolipin) (Ramsey et al., 2006; Venkatachalam and ...
B. Çiğ +2 more
semanticscholar +1 more source
TRP Channels Entering the Structural Era [PDF]
, 2013 Transient receptor potential (TRP) channels are important in many neuronal and non-neuronal physiological processes. The past 2 years have seen much progress in the use of structural biology techniques to elucidate molecular mechanisms of TRP channel ...
Gaudet, Rachelle
core +1 more source
Transient Receptor Potential channels (TRP) in GtoPdb v.2021.3
IUPHAR/BPS Guide to Pharmacology CITE, 2021 The TRP superfamily of channels (nomenclature as agreed by NC-IUPHAR [159, 997]), whose founder member is the Drosophila Trp channel, exists in mammals as six families; TRPC, TRPM, TRPV, TRPA, TRPP and TRPML based on amino acid homologies.
Nathaniel T. Blair +28 more
semanticscholar +1 more source