Results 21 to 30 of about 3,392 (133)

TRP Channels: Current Perspectives in the Adverse Cardiac Remodeling [PDF]

open access: yes, 2019
Calcium is an important second messenger required not only for the excitation-contraction coupling of the heart but also critical for the activation of cell signaling pathways involved in the adverse cardiac remodeling and consequently for the heart ...
Calderón Sánchez, Eva María   +7 more
core   +1 more source

What do we know about the transient receptor potential vanilloid 2 (TRPV2) ion channel? [PDF]

open access: yes, 2013
Transient receptor potential (TRP) ion channels are emerging as a new set of membrane proteins involved in a vast array of cellular processes and regulated by a large number of physical and chemical stimuli, which involves them with sensory cell ...
Doñate-Macian, Pau   +2 more
core   +1 more source

Expression and function of transient receptor potential channels in the female bovine reproductive tract [PDF]

open access: yes, 2016
© 2016 Elsevier Inc. The epithelium lining the oviduct is critical for early reproductive events, many of which are mediated via intracellular calcium ions.
Atkin, Stephen L.   +3 more
core   +2 more sources

TRPV2 Channels Contribute to Stretch-Activated Cation Currents and Myogenic Constriction in Retinal Arterioles [PDF]

open access: yes, 2016
Purpose: Activation of the transient receptor potential channels, TRPC6, TRPM4, and TRPP1 (PKD2), has been shown to contribute to the myogenic constriction of cerebral arteries.
Curtis, Tim M.   +7 more
core   +1 more source

Involvement of TRPV3 and TRPM8 ion channel proteins in induction of mammalian cold-inducible proteins [PDF]

open access: yes, 2018
Cold-inducible RNA-binding protein (CIRP), RNA-binding motif protein 3 (RBM3) and serine and arginine rich splicing factor 5 (SRSF5) are RNA-binding proteins that are transcriptionally upregulated in response to moderately low temperatures and a variety ...
Fujita Jun   +7 more
core   +2 more sources

Functions of TRPs in retinal tissue in physiological and pathological conditions

open access: yesFrontiers in Molecular Neuroscience
The Transient Receptor Potential (TRP) constitutes a family of channels subdivided into seven subfamilies: Ankyrin (TRPA), Canonical (TRPC), Melastatin (TRPM), Mucolipin (TRPML), no-mechano-potential C (TRPN), Polycystic (TRPP), and Vanilloid (TRPV ...
Thaianne Hanah Oliveira do Nascimento   +10 more
doaj   +1 more source

Analysis of dynamic spectrum leasing for coded Bi-directional communication [PDF]

open access: yes, 2012
In this paper, we aim to present a cooperative relaying based two way wireless communication scheme which can provide both spectral and energy efficiency in future wireless networks.
Elmirghani, JMH, Hafeez, M
core   +1 more source

Danger- and pathogen-associated molecular patterns recognition by pattern-recognition receptors and ion channels of the transient receptor potential family triggers the inflammasome activation in immune cells and sensory neurons. [PDF]

open access: yes, 2015
An increasing number of studies show that the activation of the innate immune system and inflammatory mechanisms play an important role in the pathogenesis of numerous diseases.
A Becerra   +133 more
core   +3 more sources

Structural and Biochemical Consequences of Disease-Causing Mutations in the Ankyrin Repeat Domain of the Human TRPV4 Channel [PDF]

open access: yes, 2014
The TRPV4 calcium-permeable cation channel plays important physiological roles in osmosensation, mechanosensation, cell barrier formation, and bone homeostasis. Recent studies reported that mutations in TRPV4, including some in its ankyrin repeat domain (
Gaudet, Rachelle   +3 more
core   +2 more sources

Heart Failure: Epidemiology, Pathophysiology, and Management

open access: yesMedComm, Volume 7, Issue 3, March 2026.
This article takes calcium homeostasis as the point of departure to provide an overview of heart failure from three perspectives—epidemiology, pathophysiological mechanisms, and management strategies—and summarizes the current unmet needs and future directions in the field. ABSTRACT Heart failure (HF) is one of the leading causes of hospitalization and
Yujian Fan   +9 more
wiley   +1 more source

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