Results 41 to 50 of about 4,298 (244)

Disordered but rhythmic—the role of intrinsic protein disorder in eukaryotic circadian timing

open access: yesFEBS Letters, EarlyView.
Unstructured domains known as intrinsically disordered regions (IDRs) are present in nearly every part of the eukaryotic core circadian oscillator. IDRs enable many diverse inter‐ and intramolecular interactions that support clock function. IDR conformations are highly tunable by post‐translational modifications and environmental conditions, which ...
Emery T. Usher, Jacqueline F. Pelham
wiley   +1 more source

The Accuracy of Intraoral Scanners in Maxillary Defects with Different Model Variations

open access: yesDiagnostics
Background: Advances in digital technology and intraoral scanners (IOSs) have the potential to enable accurate digital impressions for patients with maxillary defects.
Sema Murat   +3 more
doaj   +1 more source

Trueness of 12 intraoral scanners in the full-arch implant impression: a comparative in vitro study

open access: yesBMC Oral Health, 2020
Background The literature has not yet validated the use of intraoral scanners (IOSs) for full-arch (FA) implant impression. Hence, the aim of this in vitro study was to assess and compare the trueness of 12 different IOSs in FA implant impression ...
Francesco Guido Mangano   +5 more
doaj   +1 more source

Effect of Printing Layer Thickness on the Trueness and Margin Quality of 3D-Printed Interim Dental Crowns

open access: yesApplied Sciences, 2021
The information in the literature on the effect of printing layer thickness on interim 3D-printed crowns is limited. In the present study, the effect of layer thickness on the trueness and margin quality of 3D-printed composite resin crowns was ...
Gülce Çakmak   +6 more
doaj   +1 more source

Multiple ETS family transcription factors bind mutant p53 via distinct interaction regions

open access: yesFEBS Letters, EarlyView.
Mutant p53 gain‐of‐function is thought to be mediated by interaction with other transcription factors. We identify multiple ETS transcription factors that can bind mutant p53 and found that this interaction can be promoted by a PXXPP motif. ETS proteins that strongly bound mutant p53 were upregulated in ovarian cancer compared to ETS proteins that ...
Stephanie A. Metcalf   +6 more
wiley   +1 more source

Effects of Trueness and Surface Microhardness on the Fitness of Ceramic Crowns

open access: yesApplied Sciences, 2020
This study aims to evaluate the fitness, surface microhardness, and trueness of crowns fabricated from three types of dental ceramic blocks (HASS Rosetta, IPS e.max CAD, and VITA Suprinity) and analyze the correlations between them.
Kunhee Lee, Keunbada Son, Kyu-bok Lee
doaj   +1 more source

The newfound relationship between extrachromosomal DNAs and excised signal circles

open access: yesFEBS Letters, EarlyView.
Extrachromosomal DNAs (ecDNAs) contribute to the progression of many human cancers. In addition, circular DNA by‐products of V(D)J recombination, excised signal circles (ESCs), have roles in cancer progression but have largely been overlooked. In this Review, we explore the roles of ecDNAs and ESCs in cancer development, and highlight why these ...
Dylan Casey, Zeqian Gao, Joan Boyes
wiley   +1 more source

Rigorous Performance Evaluation of Smartphone GNSS/IMU Sensors for ITS Applications

open access: yesSensors, 2016
With the rapid growth in smartphone technologies and improvement in their navigation sensors, an increasing amount of location information is now available, opening the road to the provision of new Intelligent Transportation System (ITS) services ...
Vassilis Gikas, Harris Perakis
doaj   +1 more source

Structural instability impairs function of the UDP‐xylose synthase 1 Ile181Asn variant associated with short‐stature genetic syndrome in humans

open access: yesFEBS Letters, EarlyView.
The Ile181Asn variant of human UDP‐xylose synthase (hUXS1), associated with a short‐stature genetic syndrome, has previously been reported as inactive. Our findings demonstrate that Ile181Asn‐hUXS1 retains catalytic activity similar to the wild‐type but exhibits reduced stability, a looser oligomeric state, and an increased tendency to precipitate ...
Tuo Li   +2 more
wiley   +1 more source

A comparative evaluation of intraoral and extraoral digital impressions: An in vivo study

open access: yesThe Journal of Indian Prosthodontic Society, 2018
Aim: The accuracy of a dental impression is determined by two factors: “trueness” and “precision.” The scanners used in dentistry are relatively new in market, and very few studies have compared the “precision” and “trueness” of intraoral scanner with ...
Gursharan Kaur Sason   +3 more
doaj   +1 more source

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