Results 141 to 150 of about 2,546 (170)

Intrinsically Mitochondria‐Targeting Nanozyme via Coordination‐Assembly of Natural Quercetin for Cascade Antioxidant Therapy of Cerebral Ischemia‐Reperfusion Injury

Advanced Science, EarlyView.
This study uncovers that quercetin naturally targets mitochondria. By coordinating quercetin with Fe3+, we engineer an ultrasmall cascade nanozyme (MCN) with superoxide dismutase‐catalase activities. MCN crosses the damaged blood–brain barrier, scavenges mitochondrial ROS, prevents mitochondrial DNA leakage, and blocks the cGAS‐STING pathway, thereby ...
Wenxuan Zheng, Zhicheng Wang, Xin Zhou, Shuya Wang, Xiaojing Shi, Tingli Xiong, Ruishi Li, Yuting Lin, Zhen Chen, Jiawen Wei, Fei Li, Jinwen Ge, Kelong Ai, Chong Liu, Guiming Deng   +14 more
wiley   +1 more source

The Effect of SARS-COV-2 Protein Fragments on the Dimerization of α-Synuclein. [PDF]

ACS Chem Neurosci
Coleman LM, Hansmann UHE.
europepmc   +1 more source

HelixSide: A Comprehensive Method for Local and Global Orientational Analysis of Proteins. [PDF]

J Chem Inf Model
Pirnes S, Hägg V, Girych M, Vattulainen I, Enkavi G.   +4 more
europepmc   +1 more source

Research on the Genetic Polymorphism and Function of <i>inlA</i> with Premature Stop Codons in <i>Listeria monocytogenes</i>. [PDF]

Foods
Liu X, Gao B, Li Z, Liang Y, Shi T, Dong Q, Chen M, Wu H, Zhang H.   +8 more
europepmc   +1 more source

Oligomerization of PER2 as a dynamic mode of regulation of the mammalian circadian clock. [PDF]

Proc Natl Acad Sci U S A
Sanyal P, Sharma D, Viswan A, Crosby P, Narayanan V, Baumgartner J, Partch CL, Sekhar A.   +7 more
europepmc   +1 more source

FatePredictor: Cell fate decision-making prediction with an ensemble deep learning model. [PDF]

Innovation (Camb)
Shen J, Chen N, Niu B, Zhong J, Liu R.
europepmc   +1 more source

Mechanism of RACK1-dependent ZAKα activation at stalled and collided ribosomes.

Mol Cell
Vind AC, Martínez JF, Wu Z, Bugai A, Mordente K, Abis G, Chamois S, Ramalho S, Pechincha C, Ryder L, Chen Q, Rasmussen M, Shi X, He D, Svejstrup JQ, Haahr P, Gatfield D, Conte MR, Jensen TH, Blasius M, Bekker-Jensen S.   +20 more
europepmc   +1 more source

Atomistic Insights into the Reactive Diffusion of CO₂ in Guanidine-Based Facilitated Transport Membranes. [PDF]

J Phys Chem C Nanomater Interfaces
Zou C, Deng X, Han Y, Lin LC.
europepmc   +1 more source