Results 81 to 90 of about 456,372 (322)

Inference for Shared-Frailty Survival Models with Left-Truncated Data [PDF]

open access: yes
Shared-frailty survival models specify that systematic unobserved determinants of duration outcomes are identical within groups of individuals. We consider random-effects likelihood-based statistical inference if the duration data are subject to left ...
Drepper, Bettina   +1 more
core   +3 more sources

Renormalisation and fixed points in Hilbert Space

open access: yes, 2003
The energies of low-lying bound states of a microscopic quantum many-body system of particles can be worked out in a reduced Hilbert space. We present here and test a specific non-perturbative truncation procedure.
Becker K W Huebsch A Sommer T   +21 more
core   +2 more sources

FGFR Like1 drives esophageal cancer progression via EMT, PI3K/Akt, and notch signalling: insights from clinical data and next‐generation sequencing analysis

open access: yesFEBS Open Bio, EarlyView.
Clinical analysis reveals significant dysregulation of FGFRL1 in esophageal cancer (EC) patients. RNAi‐coupled next‐generation sequencing (NGS) and in vitro study reveal FGFRL1‐mediated EC progression via EMT, PI3K/Akt, and Notch pathways. Functional assays confirm its role in tumor growth, migration, and invasion.
Aprajita Srivastava   +3 more
wiley   +1 more source

KLK7 overexpression promotes an aggressive phenotype and facilitates peritoneal dissemination in colorectal cancer cells

open access: yesFEBS Open Bio, EarlyView.
KLK7, a tissue kallikrein‐related peptidase, is elevated in advanced colorectal cancer and associated with shorter survival. High KLK7 levels in ascites correlate with peritoneal metastasis. In mice, KLK7 overexpression increases metastasis. In vitro, KLK7 enhances cancer cell proliferation, migration, adhesion, and spheroid formation, driving ...
Yosr Z. Haffani   +6 more
wiley   +1 more source

Mathematical Formalization and Applications to Data with Excess of Zeros and Ones of the Unit-Proportional Hazard Inflated Models

open access: yesMathematics
In this study, we model the rate or proportion of a specific phenomenon using a set of known covariates. To fit the regression model, which explains the phenomenon within the intervals (0,1), [0,1), (0,1], or [0,1], we employ a logit link function.
Guillermo Martínez-Flórez   +2 more
doaj   +1 more source

Commentary on rainbow-ladder truncation for excited states and exotics

open access: yes, 2011
Ground-state, radially-excited and exotic scalar-, vector- and flavoured-pseudoscalar-mesons are studied in rainbow-ladder truncation using an interaction kernel that is consonant with modern DSE- and lattice-QCD results. The inability of this truncation
A. Cucchieri   +9 more
core   +1 more source

Scoring rules, ballot truncation, and the truncation paradox

open access: yesPublic Choice, 2022
A voting rule that permits some voters to favor a candidate by providing only the initial segment of their sincere rankings is said to be vulnerable to the truncation paradox. In this paper, we consider four models for counting truncated ballots, optimistic, pessimistic (the most common), averaged, and round-down.
openaire   +2 more sources

The cooperative regulation of miR‐221 by APE1 and AUF1 impacts p27Kip1 defining a miR signature relevant for cervical cancer

open access: yesFEBS Open Bio, EarlyView.
A regulatory axis involving APE1, AUF1, and miR‐221 is proposed. Pri‐miR‐221 is processed by DROSHA and DICER to generate mature miR‐221, which targets p27Kip1 mRNA. APE1 and AUF1 compete for pre‐miR‐221 binding. Reduced APE1/AUF1 levels impair miR‐221 biogenesis, decrease p27Kip1 mRNA degradation, and promote cell cycle progression, chemoresistance ...
Matilde Clarissa Malfatti   +3 more
wiley   +1 more source

An analytical connection between temporal and spatio-temporal growth rates in linear stability analysis

open access: yes, 2013
We derive an exact formula for the complex frequency in spatio-temporal stability analysis that is valid for arbitrary complex wave numbers. The usefulness of the formula lies in the fact that it depends only on purely temporal quantities, which are ...
Naraigh, Lennon O, Spelt, Peter D. M.
core   +3 more sources

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