Results 61 to 70 of about 129,248 (267)

Models for truncated counts [PDF]

open access: yesJournal of Applied Econometrics, 1991
AbstractThis paper examines a class of maximum‐likelihood regression estimators for count data from truncated samples. Estimators for the truncated Poisson and negative binomial distributions are illustrated. Simulation results are given to illustrate the magnitude of the bias that may result from the failure to account for overdispersion in truncated ...
Grogger, J T, Carson, Richard T
openaire   +1 more source

The crystal structure of the Borrelia burgdorferi nicotinamidase BBE22 resolves a long‐standing annotation error

open access: yesFEBS Open Bio, EarlyView.
The crystal structure of Borrelia burgdorferi nicotinamidase (PncA/BBE22) reveals the correct full‐length protein initiated from a non‐canonical AUU start codon. The structure validates previous biochemical findings and resolves a long‐standing annotation error, demonstrating that the truncated database sequence is structurally incompatible with the ...
Kalvis Brangulis
wiley   +1 more source

Mathematical Formalization and Applications to Data with Excess of Zeros and Ones of the Unit-Proportional Hazard Inflated Models

open access: yesMathematics
In this study, we model the rate or proportion of a specific phenomenon using a set of known covariates. To fit the regression model, which explains the phenomenon within the intervals (0,1), [0,1), (0,1], or [0,1], we employ a logit link function.
Guillermo Martínez-Flórez   +2 more
doaj   +1 more source

Quotients of dilworth truncations

open access: yesJournal of Combinatorial Theory, Series B, 1990
Sufficient conditions are given for an elementary quotient of the k-th Dilworth truncation of a matroid M to be the k-th Dilworth truncation of a quotient of M. As special cases, contractions of Dilworth truncations and principal truncations by connected flats of Dilworth truncations are characterised as Dilworth truncations of certain matroids.
openaire   +1 more source

Guiding AlphaFold to predict how Munc13‐1 opens Syntaxin‐1

open access: yesFEBS Open Bio, EarlyView.
The syntaxin‐1 Habc‐domain (orange), linker (pink) and SNARE motif (yellow) form a closed conformation that binds to Munc18‐1 (violet) and is opened by the Munc13‐1 MUN domain (cyan) to form the SNARE complex that triggers neurotransmitter release.
Madhurima Chattopadhyay   +2 more
wiley   +1 more source

Small RNA pathways in mammalian oocytes

open access: yesFEBS Open Bio, EarlyView.
Three distinct small RNA pathways operate in mammalian oocytes: RNAi interference (RNAi), the microRNA (miRNA) pathway, and the PIWI‐associated RNA (piRNA) pathway. These pathways use small RNAs to guide sequence‐specific repression and contribute to oocyte biology by targeting genes and mobile elements or appear insignificant since different ...
Petr Svoboda, Josef Pasulka
wiley   +1 more source

Conceptualizing resistance to the Americanization of finance in advanced economy states: The case of the Canadian-dollar system

open access: yesFinance and Society
This article derives four propositions for conceptualizing resistance to the Americanization of finance in advanced economy states. Resistance entails truncation of market-based financial innovations in line with political profit-sharing arrangements ...
Dustin Fergusson-Vaux
doaj   +1 more source

Molecular characterization of covRS mutations in M1UK Streptococcus pyogenes

open access: yesFEBS Open Bio, EarlyView.
Group A Streptococcus (GAS) acquires covRS mutations driving a hypervirulent bacterial state, frequently associated with invasive disease‐like necrotizing fasciitis. We demonstrate that the newly emerged M1UK GAS lineage can also acquire these mutations.
Jarrad Pritchard   +12 more
wiley   +1 more source

Loss of AMBRA1 activates MAPK and angiogenesis signaling pathways in melanoma cells

open access: yesFEBS Open Bio, EarlyView.
Loss of AMBRA1 in melanoma cells activates multiple oncogenic pathways associated with tumor progression. Transcriptomic and protein network analyses revealed that AMBRA1 depletion enhances MAPK/ERK signaling, angiogenesis, TGF‐β/EMT signaling, and Wnt/axon guidance pathways.
Milad Ibrahim   +4 more
wiley   +1 more source

On truncations for weakly ergodic inhomogeneous birth and death processes

open access: yesInternational Journal of Applied Mathematics and Computer Science, 2014
We investigate a class of exponentially weakly ergodic inhomogeneous birth and death processes. We consider special transformations of the reduced intensity matrix of the process and obtain uniform (in time) error bounds of truncations. Our approach also
Zeifman Alexander   +3 more
doaj   +1 more source

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