Results 61 to 70 of about 129,011 (267)

Modeling and measurements of angular truncation for an aerosol albedometer [PDF]

Journal of the European Optical Society-Rapid Publications, 2012
In this work, we examine the angular truncation behavior and present correction factors for the aerosol albedometer previously developed in our laboratory. This new instrument makes simultaneous measurement of extinction and scattering coefficients (bext
Qian F., Ma L., Thompson J. E.
doaj   +1 more source

Finding novel vulnerabilities of hypomorphic BRCA1 alleles

Molecular Oncology, EarlyView.
Synthetic lethality screens performed to identify novel vulnerabilities often model complete gene loss, thereby overlooking patient‐derived hypomorphic mutations. In this study, we have performed genome‐wide CRISPR screens on BRCA1 hypomorphic mutations, showing BRCA1I26A behaves like wild‐type, while BRCA1R1699Q mimics deficiency. Furthermore, we have
Anne Schreuder, Klaas de Lint, Hồ Mỹ Phúc Võ, Mariana M. Góis, Rosalie A. Kampen, Marta San Martin Alonso, Ilse Nootenboom, Veronica Garzero, Tiemen J. Wendel, Rob M. F. Wolthuis, Sylvie M. Noordermeer   +10 more
wiley   +1 more source

Oncogenic DMTF1β promotes cancer cell motility by regulating autophagy through ULK1 stabilization

Molecular Oncology, EarlyView.
In the current study, we demonstrate that the oncogene DMTF1β regulates ULK1 stability by reducing its proteasomal degradation in cancer cells. This stabilization enables ULK1 to induce autophagy, which in turn facilitates cancer cell migration. Consequently, reduced DMTF1β levels lead to decreased autophagy and impaired cancer cell migration.
Jun Xu, Nicolas J. Niklaus, Anna M. Schläfli, Igor Tokarchuk, Magali Humbert, Federico La Manna, Bich Vu, David Maul, Ramin Radpour, Marianna Kruithof‐de Julio, Inti Zlobec, Jörn Dengjel, Bruce E. Torbett, Mario P. Tschan   +13 more
wiley   +1 more source

Renaming as a factor of successful marketing communication

Неофилология
INTRODUCTION. In 2022, due to the political situation in the world, many foreign brands were forced to leave the Russian market. After some time, some of them returned, undergoing renaming – changing their trade name.
A. V. Zavadskaya
doaj   +1 more source

Models for truncated counts [PDF]

Journal of Applied Econometrics, 1991
AbstractThis paper examines a class of maximum‐likelihood regression estimators for count data from truncated samples. Estimators for the truncated Poisson and negative binomial distributions are illustrated. Simulation results are given to illustrate the magnitude of the bias that may result from the failure to account for overdispersion in truncated ...
Grogger, J T, Carson, Richard T
openaire   +1 more source

Exon 7 splicing of ERα predicts poor prognosis and increases phenotypic heterogeneity in luminal a subtype breast cancer

FEBS Open Bio, EarlyView.
ERα splice variant ERα∆7 lacks the C‐terminus, and its expression may change phenotypes of breast cancers. Our results showed that ERα∆7 is found in the luminal A subtype, and elevated ERα∆7 levels are linked to improved cell survival with lower proliferation and migration.
Long Wai Tsui, Taobo Hu, Thomson Christian Husein, Wai Hei Shek, Bingrong Chen, Depeng Wang, Shu Wang, Weichuan Yu, Xiaodan Fan, Mengping Long, Toyotaka Ishibashi   +10 more
wiley   +1 more source

Language form compression in modern Russian speech

Russian Language Studies
Compressive word formation results from the active tendency to save speech effort and, accordingly, to save linguistic means, which makes its research relevant.
Elena M. Markova
doaj   +1 more source

Proteasomal degradation of intracellularly expressed Amblyomin‐X limits suicide gene therapy potential in melanoma cells

FEBS Open Bio, EarlyView.
This study explores the feasibility of expressing the antitumoral protein Amblyomin‐X through a suicide gene therapy approach and investigates its intracellular fate after gene delivery. Although the gene is efficiently expressed, melanoma cells rapidly degrade the Amblyomin‐X protein via proteasome activity.
Victor Dal Posolo Cinel, Carlos DeOcesano Pereira, Aline Ramos Maia Lobba, Melissa Regina Fessel, Ana Marisa Chudzinski‐Tavassi   +4 more
wiley   +1 more source

The Bounded Laplace Mechanism in Differential Privacy

The Journal of Privacy and Confidentiality, 2019
The Laplace mechanism is the workhorse of differential privacy, applied to many instances where numerical data is processed. However, the Laplace mechanism can return semantically impossible values, such as negative counts, due to its infinite support ...
Naoise Holohan, Spiros Antonatos, Stefano Braghin, Pól Mac Aonghusa   +3 more
doaj   +1 more source

Quotients of dilworth truncations

Journal of Combinatorial Theory, Series B, 1990
Sufficient conditions are given for an elementary quotient of the k-th Dilworth truncation of a matroid M to be the k-th Dilworth truncation of a quotient of M. As special cases, contractions of Dilworth truncations and principal truncations by connected flats of Dilworth truncations are characterised as Dilworth truncations of certain matroids.
openaire   +1 more source