Results 81 to 90 of about 764,078 (329)

Universal consistent truncation for 6d/7d gauge/gravity duals [PDF]

, 2015
A bstractRecently, AdS7 solutions of IIA supergravity have been classified; there are infinitely many of them, whose expression is known analytically, and with internal space of S3 topology. Their field theory duals are six-dimensional (1,0) SCFT’s.
A. Passias, A. Rota, A. Tomasiello
semanticscholar   +1 more source

Deterministic Truncation of Linear Matroids [PDF]

International Colloquium on Automata, Languages and Programming, 2014
Let M=(E,I) be a matroid of rank n. A k-truncation of M is a matroid M′=(E,I′) such that for any A⊆ E, A∈ ∈I′ if and only if |A|≤ k and A∈ I. Given a linear representation, A, of M, we consider the problem of finding a linear representation, Ak, of the k-
D. Lokshtanov, P. Misra, Fahad Panolan, Saket Saurabh   +3 more
semanticscholar   +1 more source

CD47 promotes mitogen‐activated protein kinase and epithelial‐to‐mesenchymal transition molecular programs to drive prometastatic phenotypes in non‐small cell lung cancer

Molecular Oncology, EarlyView.
Beyond its role in immune evasion, this study identified that CD47 drives tumor‐intrinsic signaling in non‐small cell lung cancer (NSCLC). Transcriptomic profiling and functional studies revealed that CD47 regulates cell adhesion, migration, and metastasis through an ERK–EMT signaling axis.
Asa P.Y. Lau, Lilian G. Zhai, Ryunosuke Hoshi, Zackary Rousseau, Abraam Zakhary, Yin Fang Wu, Rola M. Saleeb, Heyu Ni, Kelsie L. Thu   +8 more
wiley   +1 more source

Physiological C-terminal truncation of α-synuclein potentiates the prion-like formation of pathological inclusions

Journal of Biological Chemistry, 2018
α-Synuclein (αsyn) aggregates into toxic fibrils in multiple neurodegenerative diseases where these fibrils form characteristic pathological inclusions such as Lewy bodies (LBs).
Z. Sorrentino, Niran Vijayaraghavan, Kimberly-Marie M. Gorion, Cara J. Riffe, Kevin H. Strang, J. Caldwell, B. Giasson   +6 more
semanticscholar   +1 more source

Heterozygous loss‐of‐function alleles associate the conserved 3′‐5′ exoribonuclease EXOSC10 with hypersensitivity to the anticancer drug 5‐fluorouracil

Molecular Oncology, EarlyView.
EXOSC10, an essential nuclear RNA exosome‐associated 3′‐5′ exoribonuclease, is inhibited by the anticancer drug 5‐fluorouracil (5‐FU), and EXOSC10 depletion increases 5‐FU sensitivity. The colon‐cancer variant EXOSC10S402T, located in a proteolysis motif, is stable and nuclear but nonfunctional in vivo.
Radhika Sain, Yann Le Page, Frédéric Percevault, Emmanuelle Becker, Luc Negroni, Almudena Fernandez, Marta Cantero, Diego Muñoz‐Santos, Lluís Montoliu, Cyrille Garnier, Michael Primig   +10 more
wiley   +1 more source

Renormalisation and fixed points in Hilbert Space

, 2003
The energies of low-lying bound states of a microscopic quantum many-body system of particles can be worked out in a reduced Hilbert space. We present here and test a specific non-perturbative truncation procedure.
Becker K W Huebsch A Sommer T, Bogner S, Brandow B H, Feshbach H, Glazek S D, Heiss W D, Hofmann H M, Jean Richert, Johnson M B, Kato T, Lin H-Q, Mueller H Piekarewicz J Shepard J R, Oberlechner G, Rau J, Sachdev S, Schucan T H, Schucan T H, Schultz T D, Suzuki K, Tarek Khalil, Yuzbashyan E A, Znojil M Bila H Jakubsky V   +21 more
core   +2 more sources

USP29‐regulated noncanonical stabilization of the hypoxia‐inducible factor‐α in aggressive prostate cancer

Molecular Oncology, EarlyView.
We identify USP29 as the only DUB mirroring CA9 expression, a marker of hypoxia and HIF pathway activation associated with PCA aggressiveness. USP29 stabilizes HIF‐1α and HIF‐2α via a noncanonical mechanism that is independent of PHD/pVHL activity yet relies on proteasomal regulation, establishing USP29 as a previously unrecognized regulator of hypoxic
Amelie S Schober, Leire Moreno‐Cugnon, Laura Martínez‐Pérez, Amaia Ercilla, Amaia Zabala‐Letona, Adrián Vicente‐Barrueco, Maider Fagoaga‐Eugui, Saioa Garcia‐Longarte, Blanca Calle‐Ciborro, Encarnación Pérez‐Andrés, Onintza Carlevaris, Sara Pozo, Isabel Mendizabal, Ugo Mayor, Arkaitz Carracedo, Violaine Sée, Edurne Berra   +16 more
wiley   +1 more source

Renaming as a factor of successful marketing communication

Неофилология
INTRODUCTION. In 2022, due to the political situation in the world, many foreign brands were forced to leave the Russian market. After some time, some of them returned, undergoing renaming – changing their trade name.
A. V. Zavadskaya
doaj   +1 more source

Hamiltonian truncation study of the $φ^4$ theory in two dimensions [PDF]

, 2014
We defend the Fock-space Hamiltonian truncation method, which allows us to calculate numerically the spectrum of strongly coupled quantum field theories, by putting them in a finite volume and imposing a UV cutoff.
S. Rychkov, L. Vitale
semanticscholar   +1 more source

The cooperative regulation of miR‐221 by APE1 and AUF1 impacts p27Kip1 defining a miR signature relevant for cervical cancer

FEBS Open Bio, EarlyView.
A regulatory axis involving APE1, AUF1, and miR‐221 is proposed. Pri‐miR‐221 is processed by DROSHA and DICER to generate mature miR‐221, which targets p27Kip1 mRNA. APE1 and AUF1 compete for pre‐miR‐221 binding. Reduced APE1/AUF1 levels impair miR‐221 biogenesis, decrease p27Kip1 mRNA degradation, and promote cell cycle progression, chemoresistance ...
Matilde Clarissa Malfatti, Nicolò Gualandi, Gianluca Tell, Giulia Antoniali   +3 more
wiley   +1 more source