Results 81 to 90 of about 129,011 (267)

On truncations for weakly ergodic inhomogeneous birth and death processes

open access: yesInternational Journal of Applied Mathematics and Computer Science, 2014
We investigate a class of exponentially weakly ergodic inhomogeneous birth and death processes. We consider special transformations of the reduced intensity matrix of the process and obtain uniform (in time) error bounds of truncations. Our approach also
Zeifman Alexander   +3 more
doaj   +1 more source

Mincing words: Balancing recovery and deletion in word truncation

open access: yesGlossa, 2018
Brazilian Portuguese exhibits word truncation: e.g., the word cruzeiro ‘cruise’ results in the truncated form cruza, where the vowel -a is added to the truncated stem cruz-. Gonçalves (2011) claims that truncated words preserve the onset of the rightmost
Jackson L. Lee, Mike Pham
doaj   +2 more sources

Molecular characterization of covRS mutations in M1UK Streptococcus pyogenes

open access: yesFEBS Open Bio, EarlyView.
Group A Streptococcus (GAS) acquires covRS mutations driving a hypervirulent bacterial state, frequently associated with invasive disease‐like necrotizing fasciitis. We demonstrate that the newly emerged M1UK GAS lineage can also acquire these mutations.
Jarrad Pritchard   +12 more
wiley   +1 more source

Loss of AMBRA1 activates MAPK and angiogenesis signaling pathways in melanoma cells

open access: yesFEBS Open Bio, EarlyView.
Loss of AMBRA1 in melanoma cells activates multiple oncogenic pathways associated with tumor progression. Transcriptomic and protein network analyses revealed that AMBRA1 depletion enhances MAPK/ERK signaling, angiogenesis, TGF‐β/EMT signaling, and Wnt/axon guidance pathways.
Milad Ibrahim   +4 more
wiley   +1 more source

Eigenvalue −1 of the Vertex Quadrangulation of a 4-Regular Graph

open access: yesAxioms
The vertex quadrangulation QG of a 4-regular graph G visually looks like a graph whose vertices are depicted as empty squares, and the connecting edges are attached to the corners of the squares.
Vladimir R. Rosenfeld
doaj   +1 more source

Super‐Refractory Status Epilepticus (SRSE) in a Patient With Compound Heterozygous OPA1 Variants: Case Report and Literature Review

open access: yesAnnals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Super‐Refractory Status Epilepticus (SRSE) is a rare, life‐threatening neurological emergency with unclear etiology in many cases. Mitochondrial dysfunction, often due to disease‐causing genetic variants, is increasingly recognized as a cause, with each gene producing distinct pathophysiological mechanisms.
Pouria Mohammadi   +2 more
wiley   +1 more source

Hypocoristic Formation in Gujarati

open access: yesCatalan Journal of Linguistics
This paper examines the morphology and phonology of hypocoristic formation in Gujarati, an Indo-Aryan language, within the framework of Optimality Theory and applying the Theory of Prosodic Morphology (McCarthy & Prince 1986).
Hemangini
doaj   +1 more source

Cyclisation Increases the Stability of the Sea Anemone Peptide APETx2 but Decreases Its Activity at Acid-Sensing Ion Channel 3

open access: yesMarine Drugs, 2012
APETx2 is a peptide isolated from the sea anemone <em>Anthopleura elegantissima</em>.<em> </em>It is the most potent and selective inhibitor of acid-sensing ion channel 3 (ASIC3) and it is currently in preclinical studies as a ...
Lachlan D. Rash   +5 more
doaj   +1 more source

Developmental and Epileptic Encephalopathy due to Biallelic Pathogenic Variants in PIGM

open access: yesAnnals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective PIGM encodes a critical enzyme in the glycosylphosphatidylinositol (GPI)‐anchor biosynthesis pathway. While promoter‐region mutations in PIGM have been associated with a relatively mild phenotype characterized by portal vein thrombosis and absence seizures, recent evidence suggests that coding‐region mutations result in a more severe
Júlia Sala‐Coromina   +11 more
wiley   +1 more source

Cracking the Code: Genotype–Phenotype Correlation Models in Sarcoglycanopathies

open access: yesAnnals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Sarcoglycanopathies are among the most severe limb‐girdle muscular dystrophies (LGMD), though milder presentations have been described. These diseases are primarily caused by missense variants, but the limited predictability of their effect on protein maturation, complex formation, and transport has hindered reliable genotype ...
Leonela Luce   +72 more
wiley   +1 more source

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