Results 181 to 190 of about 4,252,841 (287)

Trust-building as a Keystone Activity in Beaver-related Restoration Practice. [PDF]

Environ Manage
Erickson BD, Jones MS.
europepmc   +1 more source

Analysing the significance of small conformational changes and low occupancy states in serial crystallographic data

FEBS Open Bio, EarlyView.
This protocol paper outlines methods to establish the success of a time‐resolved serial crystallographic experiment, by means of statistical analysis of timepoint data in reciprocal space and models in real space. We show how to amplify the signal from excited states to visualise structural changes in successful experiments.
Jake Hill, Yelyzaveta Pulnova, Elke De Zitter, Helen M. Ginn, Briony A. Yorke   +4 more
wiley   +1 more source

Impact of tissue staining and scanner variation on the performance of pathology foundation models: a study of sarcomas and their mimics. [PDF]

J Pathol Clin Res
Chai B, Chen J, Cool P, Oumlil F, Tollitt A, Steiner DF, Chakraborti T, Flanagan AM.   +7 more
europepmc   +1 more source

Digital twins to accelerate target identification and drug development for immune‐mediated disorders

FEBS Open Bio, EarlyView.
Digital twins integrate patient‐derived molecular and clinical data into personalised computational models that simulate disease mechanisms. They enable rapid identification and validation of therapeutic targets, prediction of drug responses, and prioritisation of candidate interventions.
Anna Niarakis, Philippe Moingeon
wiley   +1 more source

Guide on Selection of Optimal Motivational Themes for Use in a Clinical Trial Recruiting Black US Adults: Survey Study.

J Med Internet Res
Harry T, Cao J, Hussain Z, Turkson-Ocran RN, Juraschek SP, Lahey TP, Plante TB, Feng Y.   +7 more
europepmc   +1 more source

Patient perspectives about deployment of artificial intelligence decision support tools in a safety-net healthcare system. [PDF]

JAMIA Open
Phelps N, Vossler P, Kothari A, Steineman K, Goldman S, Gasga A, Ehrlich S, Kanzaria H, Adler-Milstein J, Feng J, Nong P, Zier LS.   +11 more
europepmc   +1 more source

Evolutionarily divergent DUF4465 domains have a common vitamin B12‐binding function

FEBS Open Bio, EarlyView.
We show that DUF4465 family proteins, widespread across bacteria from gut microbiomes, hydrothermal vents, and soil, share a common vitamin B12‐binding function. These augmented β‐jellyroll proteins bind vitamin B12 via extended loops. Our findings establish sequence‐diverse DUF4465 proteins as a widespread class of B12‐binding proteins, highlighting ...
Charlea Clarke, Michal Banasik, Rokas Juodeikis, Martin J. Warren, Richard W. Pickersgill   +4 more
wiley   +1 more source

Navigating COVID-19: Association between public perceptions of preventive measures and delayed or foregone care among young and middle-aged Korean adults in the early phase of the pandemic. [PDF]

PLoS One
Hwang J.
europepmc   +1 more source

Mass spectrometry based identification of AMP‐O‐Tris generated by Thermococcus onnurineus Cas10

FEBS Open Bio, EarlyView.
Isolated Thermococcus onnurineus Cas10 generates the noncanonical ATP‐derived product AMP‐O‐Tris while in Tris‐containing buffer as identified via mass spectrometry, revealing relaxed nucleophile selectivity under isolated conditions. These findings suggest that multiprotein Csm complex assembly restricts Cas10 reactivity toward canonical cyclic ...
Su‐Jin Lee, Ga Seul Lee, JinHan Kim, Kwang‐Hyun Park, Seong‐Ryung Go, Jeong Hee Moon, Eui‐Jeon Woo   +6 more
wiley   +1 more source

Error-Tolerant Leadership in Public Health: How Tolerance From Leaders Strengthens Healthcare Workers' Collectivism, Colleague Trust, and Job Satisfaction. [PDF]

Int J Public Health
Zhang Y, Huang J, Hao K.
europepmc   +1 more source