Results 51 to 60 of about 750,485 (276)
Molecular Oncology, EarlyView.Monitoring circulating tumor DNA (ctDNA) in patients with operable breast cancer can reveal disease relapse earlier than radiology in a subset of patients. The failure to detect ctDNA in some patients with recurrent disease suggests that ctDNA could serve as a supplement to other monitoring approaches.
Kristin Løge Aanestad +35 more
wiley +1 more source
Molecular Oncology, EarlyView.The cancer problem is increasing globally with projections up to the year 2050 showing unfavourable outcomes in terms of incidence and cancer‐related deaths. The main challenges are prevention, improved therapeutics resulting in increased cure rates and enhanced health‐related quality of life.
Ulrik Ringborg +43 more
wiley +1 more source
Telling the truth: why disclosure matters in chronic kidney disease [PDF]
British Journal of General Practice, 2012 ![][1] The dynamics of the doctor–patient relationship have evolved over recent decades from a model of benevolent paternalism to a framework centred around shared decision making,1 for which patient awareness of their diagnoses, and hence disclosure of diagnoses by healthcare professionals, are prerequisites.
Zeinab, Abdi +2 more
openaire +2 more sources
Molecular Oncology, EarlyView.Pharmacologic ascorbate (vitamin C) increases ROS, disrupts cellular metabolism, and induces DNA damage in CRPC cells. These effects sensitize tumors to PARP inhibition, producing synergistic growth suppression with olaparib in vitro and significantly delayed tumor progression in vivo. Pyruvate rescue confirms ROS‐dependent activity.
Nicolas Gordon +13 more
wiley +1 more source
Molecular Oncology, EarlyView.This study shows that copy number variations (CNVs) can be reliably detected in formalin‐fixed paraffin‐embedded (FFPE) solid cancer samples using ultra‐low‐pass whole‐genome sequencing, provided that key (pre)‐analytical parameters are optimized.
Hanne Goris +10 more
wiley +1 more source
Disclosure of true medical information: the case of Bangladesh
BMC Medical EthicsBackground Truth-telling in health care is about providing patients with accurate information about their diagnoses and prognoses to enable them to make decisions that can benefit their overall health.
Sanwar Siraj, Kristien Hens, Yousuf Ali
doaj +1 more source
Molecular Oncology, EarlyView.Single circulating tumor cells (sCTCs) from high‐grade serous ovarian cancer patients were enriched, imaged, and genomically profiled using WGA and NGS at different time points during treatment. sCTCs revealed enrichment of alterations in Chromosomes 2, 7, and 12 as well as persistent or emerging oncogenic CNAs, supporting sCTC identity.
Carolin Salmon +9 more
wiley +1 more source
Liwanag sa Dilim: Days of Darkness, Night of Light!
Philippine Journal of Otolaryngology Head and Neck Surgery, 2022 Light one candle for the strength that we need To never become our own foe And light one candle for those who are suffering Pain we learned so long ago Light one candle for all we believe in That anger not tear us apart And light ...
José Florencio Lapeña
doaj
Overview of molecular signatures of senescence and associated resources: pros and cons
FEBS Open Bio, EarlyView.Cells can enter a stress response state termed cellular senescence that is involved in various diseases and aging. Detecting these cells is challenging due to the lack of universal biomarkers. This review presents the current state of senescence identification, from biomarkers to molecular signatures, compares tools and approaches, and highlights ...
Orestis A. Ntintas +6 more
wiley +1 more source
Delivering Bad News: Emotional Perspective and Coping Strategies of Medical Students
Psychology Research and Behavior Management, 2023 Krzysztof Sobczak,1 Marcin Trzciński,2 Agata Kotłowska,2 Julia Lenkiewicz,2 Oliwia Lenkiewicz,2 Julia Przeniosło,2 Jan Plenikowski2 1Department of Sociology of Medicine & Social Pathology, Medical University of Gdansk, Gdansk, Poland;
Sobczak K +6 more
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