Results 61 to 70 of about 167,118 (269)

Amélioration de la technique de dissection du tractus digestif et des glandes salivaires des glossines pour la mise en évidence des divers stades de développement des trypanosomes

Revue d’Elevage et de Médecine Vétérinaire des Pays Tropicaux, 1994
Les auteurs décrivent une technique améliorée de dissection de l'intestin moyen et des glandes salivaires des glossines. En ajoutant à la dissection le proventricule, la méthode permet d'obtenir un tableau plus complet du développement des trypanosomes ...
J.M.L. Kazadi, P. Elsen, M. Jochems, J. Van Hees, Jan Van Den Abbeele, P. Kageruka   +5 more
doaj   +1 more source

Molecular variation of Trypanosoma brucei subspecies as revealed by AFLP fingerprinting [PDF]

, 2002
Genetic analysis of Trypanosoma spp. depends on the detection of variation between strains. We have used the amplified fragment length polymorphism (AFLP) technique to develop a convenient and reliable method for genetic characterization of Trypanosome ...
Agbo, E.E.C., Claassen, H.J.H.M., Majiwa, P.A.O., Pas, M.F.W., te   +3 more
core   +4 more sources

Rhenium Complexes as Antimicrobial Agents

Helvetica Chimica Acta, EarlyView.
Rhenium complexes are stepping into the fight against superbugs. Our new review explores how these metallic complexes could inspire the next generation of antimicrobial therapies. ABSTRACT The escalating crisis of antimicrobial resistance (AMR) necessitates the exploration of unconventional therapeutic scaffolds.
Fabio Zobi, Gozde Demirci, Marija Rasic
wiley   +1 more source

P-type transport ATPases in Leishmania and Trypanosoma

Parasite, 2019
P-type ATPases are critical to the maintenance and regulation of cellular ion homeostasis and membrane lipid asymmetry due to their ability to move ions and phospholipids against a concentration gradient by utilizing the energy of ATP hydrolysis.
Meade John C.
doaj   +1 more source

The trypanosomal transferrin receptor of trypanosoma brucei : a review [PDF]

, 2019
Iron is an essential element for life. Its uptake and utility requires a careful balancing with its toxic capacity, with mammals evolving a safe and bio-viable means of its transport and storage. This transport and storage is also utilized as part of the
Kariuki, Christopher K., Magez, Stefan, Stijlemans, Benoit   +2 more
core   +2 more sources

Calpain Proteases and the Evolving Signaling Network in Insect Embryonic Patterning

Journal of Experimental Zoology Part B: Molecular and Developmental Evolution, EarlyView.
Insect embryonic Dorsal‐Ventral (DV) patterning relies on the BMP and Toll pathways to different extents. Calcium‐dependent cystein proteases of the Calpain family also exert an important function to pattern the DV axis. In Drosophila, Calpain A cleaves the Cactus/IkappaB inhibitor and modifies Toll signals in ventral regions of the embryo. In Rhodnius
Alison Julio, Helena Araujo
wiley   +1 more source

Broadening the spectrum of ivermectin: Its effect on Trypanosoma cruzi and related trypanosomatids

Frontiers in Cellular and Infection Microbiology, 2022
Chagas disease is an endemic American parasitosis, caused by Trypanosoma cruzi. The current therapies, benznidazole (BZN) and nifurtimox (NFX), show limited efficacy and multiple side effects. Thus, there is a need to develop new trypanocidal strategies.
Laura Fraccaroli, María Daniela Ruiz, Virginia Gabriela Perdomo, Agustina Nicole Clausi, Darío Emmanuel Balcazar, Luciana Larocca, Carolina Carrillo   +6 more
doaj   +1 more source

Molecular and antigenic characterization of Trypanosoma cruzi TolT proteins [PDF]

, 2018
Background: TolT was originally described as a Trypanosoma cruzi molecule that accumulated on the trypomastigote flagellum bearing similarity to bacterial TolA colicins receptors.
Agüero, Fernan Gonzalo, Altcheh, Jaime Marcelo, Balouz, Virginia, Buscaglia, Carlos Andres, Camara, María de los Milagros, Campetella, Oscar Eduardo, Canepa, Gaspar Exequiel, Carlevaro, Giannina Alejandra, Carmona, Santiago Javier, Ciocchini, Andres Eduardo, Cortina, María Eugenia, Lobo, Mabel Maite, Melli, Luciano Jorge, Mucci, Juan Sebastián   +13 more
core   +1 more source

Calcitonin‐like diuretic hormone influences reproduction in adult female Rhodnius prolixus

Insect Science, EarlyView.
Highlights • CT/DH‐like immunoreactivity is present in female reproductive tissues • CT/DH receptor transcripts are expressed in the fat body and ovaries • RNAi knockdown of CT/DH receptors reduces egg number and hatching rate • Rhopr‐CT/DH increases RhoprVg1 and RhoprVgR expression in ovaries in vitro • Rhopr‐CT/DH stimulates oviduct contractions in a
Areej N. Al‐Dailami, Ian Orchard, Angela B. Lange   +2 more
wiley   +1 more source

Repurposing Carvedilol as a Novel Inhibitor of the Trypanosoma cruzi Autophagy Flux That Affects Parasite Replication and Survival

Frontiers in Cellular and Infection Microbiology, 2021
T. cruzi, the causal agent of Chagas disease, is a parasite able to infect different types of host cells and to persist chronically in the tissues of human and animal hosts.
Cynthia Vanesa Rivero, Cynthia Vanesa Rivero, Santiago José Martínez, Santiago José Martínez, Paul Novick, Juan Agustín Cueto, Betiana Nebaí Salassa, María Cristina Vanrell, Xiaomo Li, Carlos Alberto Labriola, Luis Mariano Polo, David M. Engman, Joachim Clos, Patricia Silvia Romano   +13 more
doaj   +1 more source