Results 61 to 70 of about 75,849 (239)

P-type transport ATPases in Leishmania and Trypanosoma

Parasite, 2019
P-type ATPases are critical to the maintenance and regulation of cellular ion homeostasis and membrane lipid asymmetry due to their ability to move ions and phospholipids against a concentration gradient by utilizing the energy of ATP hydrolysis.
Meade John C.
doaj   +1 more source

Bypassing Endocytic Barriers: Visualizing Membrane Fusion and Endosomal Escape of Cubic Phase Lipid Nanoparticles (Cubosomes)

Small, EarlyView.
This study uses advanced microscopy techniques, including transmission electron microscopy, scanning electron microscopy (SEM), cryogenic SEM, and live‐cell fluorescence imaging, to investigate lipid cubosome interactions with mammalian cells. It provides the first direct nanoscale evidence of cubosome membrane fusion with plasma and endosomal ...
Sue Lyn Yap, Chaitali Dekiwadia, Enrico Della Gaspera, Calum J. Drummond, Charlotte E. Conn, Nhiem Tran   +5 more
wiley   +1 more source

Host conservation through their parasites: molecular surveillance of vector-borne microorganisms in bats using ectoparasitic bat flies

Parasite, 2020
Most vertebrates host a wide variety of haematophagous parasites, which may play an important role in the transmission of vector-borne microorganisms to hosts.
Szentiványi Tamara, Markotter Wanda, Dietrich Muriel, Clément Laura, Ançay Laurie, Brun Loïc, Genzoni Eléonore, Kearney Teresa, Seamark Ernest, Estók Peter, Christe Philippe, Glaizot Olivier   +11 more
doaj   +1 more source

Label‐Free and Microplate‐Based Dissection of Glycan‐Virus Interactions Using Polymer‐Tethered Glyconanoparticles

Small Methods, EarlyView.
This work demonstrates the use of polymer‐tethered glycosylated gold nanoparticles for the label‐free evaluation of influenza virus binding in a simple microplate. Sialylated linear and branched glycans are integrated using a modular capture and assembly process. The microplate‐based assays are shown to correlate with biolayer interferometry and can be
Sarah‐Jane Richards, Simona Chessa, Lloyd Sayer, Irina Ivanova, Sanaz Ahmadipour, Alexander N. Baker, Marc Walker, Simone Dedola, Katherine A. Scott, Oliver Dibben, Robert A. Field, Matthew I. Gibson   +11 more
wiley   +1 more source

Evaluation of two candidate molecules—TCTP and cecropin—on the establishment of Trypanosoma brucei gambiense into the gut of Glossina palpalis gambiensis

Insect Science, EarlyView.
This study investigates the potential of enhancing the resistance of Glossina palpalis gambiensis to Trypanosoma brucei gambiense to mitigate the transmission of Human African Trypanosomiasis. We successfully cloned genes encoding proteins of interest in Sodalis strains, resulting in recombinant Sodalis (recSodalis) that were micro‐injected into the L3
François Sougal Ngambia Freitas, Linda De Vooght, Flobert Njiokou, Jan Van Den Abeele, Géraldine Bossard, Bernadette Tchicaya, Rosa Milagros Corrales, Sophie Ravel, Anne Geiger, David Berthier‐Teyssedre   +9 more
wiley   +1 more source

Stress in dipteran insects mass‐reared for sterile insect technique applications

Insect Science, EarlyView.
The connections between biotic and abiotic stress affecting mass‐reared dipteran insects and the associated stress and immunological responses. Numbers indicate the order in which the topics are discussed in this review. Abstract Stress may be viewed as the disturbance of homeostasis of an organism.
Caroline K. Mirieri, Vera I.D. Ros, Adly M.M. Abd‐Alla, Monique M. van Oers   +3 more
wiley   +1 more source

Seasonal Variation on The Prevalence and Molecular Characterization of Trypanosoma species from Rodents Trapped in Kilombero District, Tanzania

Journal of Applied Veterinary Science and Technology
Background: Trypanosomiasis is a disease mainly encountered in tropical regions and is significant to both humans and animals. Rodents and their fleas have been found to play a major role in the transmission of trypanosomiasis to humans.
Amani Juma, Abduli Katakweba, Elisa Mwega, Julius Medardus   +3 more
doaj   +1 more source

SUMOylation inTrypanosoma brucei

PeerJ, 2013
Small ubiquitin like modifier (SUMO) proteins are involved in many processes in eukaryotes. We here show that Trypanosoma brucei SUMO (Tb927.5.3210) modifies many proteins. The levels of SUMOylation were unaffected by temperature changes but were increased by severe oxidative stress.
Dorothea Droll, Cornelia Klein, Christine Clayton   +2 more
openaire   +4 more sources

Dual Role of Natural Killer Cells in Early Pregnancy: Immunopathological Implications and Therapeutic Potential in Recurrent Spontaneous Abortion and Recurrent Implantation Failure

Cell Proliferation, EarlyView.
This article elaborates on the role of NK cells in early pregnancy from multiple perspectives, including molecular mechanisms and therapeutic interventions. It also discusses how NK cell dysfunction contributes to RSA and RIF, aiming to provide insights for future research on NK cell mechanisms and clinical treatment of RSA and RIF.
Defeng Guan, Zhou Chen, Yuhua Zhang, Wenjie Sun, Lifei Li, Xia Huang   +5 more
wiley   +1 more source

Identification of a new fish trypanosome from the large yellow croaker (Larimichthys crocea) and description of its impact on host pathology, blood biochemical parameters and immune responses

Parasite
The aim of this study was to clarify the taxonomic identification of a hemoflagellate and assess the effect of trypanosome infection on Larimichthys crocea. Giemsa staining showed the presence of three morphotypes of trypomastigotes. The trypanosomes had
Yang Xiaoao, Qi Pengzhi, Tao Zhen, Zhang Qingwei, Wang Yanjie, Zhu Denghui, Yan Xiaojun, Fu Peipei, Guo Baoying   +8 more
doaj   +1 more source