Results 61 to 70 of about 167,875 (235)

Repurposing Carvedilol as a Novel Inhibitor of the Trypanosoma cruzi Autophagy Flux That Affects Parasite Replication and Survival

open access: yesFrontiers in Cellular and Infection Microbiology, 2021
T. cruzi, the causal agent of Chagas disease, is a parasite able to infect different types of host cells and to persist chronically in the tissues of human and animal hosts.
Cynthia Vanesa Rivero   +13 more
doaj   +1 more source

Development of a recombinase polymerase amplification lateral flow assay for the detection of active Trypanosoma evansi infections [PDF]

open access: yes, 2020
Author summary Neglected tropical diseases (NTDs) affecting humans and/or domestic animals severely impair the socio-economic development of endemic areas. One of these diseases, animal trypanosomosis, affects livestock and is caused by the parasites of
Goossens, Julie   +5 more
core   +1 more source

Does native Trypanosoma cruzi calreticulin mediate growth inhibition of a mammary tumor during infection? [PDF]

open access: yes, 2016
Indexación: Web of Science.Background: For several decades now an antagonism between Trypanosoma cruzi infection and tumor development has been detected. The molecular basis of this phenomenon remained basically unknown until our proposal that T.
A Colombo   +42 more
core   +1 more source

Amélioration de la technique de dissection du tractus digestif et des glandes salivaires des glossines pour la mise en évidence des divers stades de développement des trypanosomes

open access: yesRevue d’Elevage et de Médecine Vétérinaire des Pays Tropicaux, 1994
Les auteurs décrivent une technique améliorée de dissection de l'intestin moyen et des glandes salivaires des glossines. En ajoutant à la dissection le proventricule, la méthode permet d'obtenir un tableau plus complet du développement des trypanosomes ...
J.M.L. Kazadi   +5 more
doaj   +1 more source

Biological features of TcM: A new Trypanosoma cruzi isolate from Argentina classified into TcV lineage

open access: yesCurrent Research in Microbial Sciences, 2022
Trypanosoma cruzi, the etiologic agent of Chagas disease (CD) presents a wide genetic and phenotypic diversity that is classified into seven lineages or discrete typing units (DTU: TcI to TcVI and Tcbat).
Santiago José Martinez   +5 more
doaj   +1 more source

The Ly49E receptor inhibits the immune control of acute Trypanosoma cruzi infection [PDF]

open access: yes, 2016
The protozoan parasite Trypanosoma cruzi circulates in the blood upon infection and invades various cells. Parasites intensively multiply during the acute phase of infection and persist lifelong at low levels in tissues and blood during the chronic phase.
Almeida   +48 more
core   +2 more sources

A CRISPR Cas9 high-throughput genome editing toolkit for kinetoplastids [PDF]

open access: yesRoyal Society Open Science, 2017
Clustered regularly interspaced short palindromic repeats (CRISPR), CRISPR-associated gene 9 (Cas9) genome editing is set to revolutionize genetic manipulation of pathogens, including kinetoplastids.
Tom Beneke   +5 more
doaj   +1 more source

New compound sets identified from high throughput phenotypic screening against three kinetoplastid parasites:an open resource [PDF]

open access: yes, 2015
Using whole-cell phenotypic assays, the GlaxoSmithKline high-throughput screening (HTS) diversity set of 1.8 million compounds was screened against the three kinetoplastids most relevant to human disease, i.e.
Alonso-Padilla, Julio   +20 more
core   +3 more sources

P-type transport ATPases in Leishmania and Trypanosoma

open access: yesParasite, 2019
P-type ATPases are critical to the maintenance and regulation of cellular ion homeostasis and membrane lipid asymmetry due to their ability to move ions and phospholipids against a concentration gradient by utilizing the energy of ATP hydrolysis.
Meade John C.
doaj   +1 more source

The burden of congenital Chagas disease and implementation of molecular diagnostic tools in Latin America [PDF]

open access: yes, 2018
It is estimated that between 8000 and 15 000 Trypanosoma cruzi infected babies are born every year to infected mothers in Chagas disease endemic countries. Currently, poor access to and performance of the current diagnostic algorithm, based on microscopy
Cruz, Israel   +7 more
core   +1 more source

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