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Curasson, Georges, Mornet, Paul
openaire +4 more sources
ABSTRACT This 36‐color flow cytometry panel is designed to characterize multiple lymphocyte compartments, with a focus on T cells, their memory subpopulations, and immune checkpoints in human whole blood samples. In clinical settings, the amount of blood available from patients for scientific research is often limited.
Marie‐Theres Thieme‐Ehlert+3 more
wiley +1 more source
Inactive trans-sialidase expression in iTS-null Trypanosoma cruzi generates virulent trypomastigotes [PDF]
Disclosing virulence factors from pathogens is required to better understand the pathogenic mechanisms involved in their interaction with the host. In the case of Trypanosoma cruzi several molecules are associated with virulence.
Bertelli, Adriano+6 more
core +1 more source
Chagas disease and leishmaniasis are neglected tropical disorders caused by the protozoans Trypanosoma cruzi and Leishmania spp. Carbonic anhydrases (CAs, EC 4.2.1.1) from these protozoans (α-TcCA and β-LdcCA) have been validated as promising targets for
Alessio Nocentini+8 more
doaj +1 more source
Objective: To investigate the prevalence of trypanosome infection and their phylogeny in Bandicota indica rats from the cadmium-contaminated area of Mae Sot and the Myanmar border.
Phuangphet Waree Molee+2 more
doaj +1 more source
The detection rate of enzymatic recombinase amplification (ERA) was better than that of the rapid diagnostic test. The ERA assay was more convenient than fluorescence quantitative PCR. The ERA assay can be used as a complementary tool for malaria screening and clinical diagnosis.
Xinxin Yang+5 more
wiley +1 more source
The trans-sialidase from Trypanosoma cruzi induces thrombocytopenia during acute Chagas' disease by reducing the platelet sialic acid contents [PDF]
Strong thrombocytopenia is observed during acute infection with Trypanosoma cruzi, the parasitic protozoan agent of American trypanosomiasis or Chagas' disease.
Campetella, O.+4 more
core +2 more sources
Trypanosomes have different ways of communicating with each other. While communication via quorum sensing, or by the release and uptake of extracellular vesicles, is widespread in nature, the phenomenon of flagellar fusion has only been observed in ...
Ruth Etzensperger+7 more
doaj +1 more source
Calpain Proteases and the Evolving Signaling Network in Insect Embryonic Patterning
Insect embryonic Dorsal‐Ventral (DV) patterning relies on the BMP and Toll pathways to different extents. Calcium‐dependent cystein proteases of the Calpain family also exert an important function to pattern the DV axis. In Drosophila, Calpain A cleaves the Cactus/IkappaB inhibitor and modifies Toll signals in ventral regions of the embryo. In Rhodnius
Alison Julio, Helena Araujo
wiley +1 more source
Molecular mechanisms underlying the control of antigenic variation in African trypanosomes [PDF]
African trypanosomes escape the host adaptive immune response by switching their dense protective coat of Variant Surface Glycoprotein (VSG). Each cell expresses only one VSG gene at a time from a telomeric expression site (ES).
Alsford+52 more
core +3 more sources