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Multiplication of Trypanosoma brucei and Trypanosoma congolense in vertebrate hosts
Transactions of the Royal Society of Tropical Medicine and Hygiene, 1969Abstract Studies on multiplication of T. brucei and T. congolense showed that trypanosomes artificially maintained in mice multiply exclusively by longitudinal fission. T. brucei and T. congolense in a rabbit and a guinea-pig as well as in sheep has, in addition to multiplication by binary fission, a developmental cycle which includes ...
M A, Soltys, P, Woo
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Studies on the carbohydrate metabolism of Trypanosoma congolense
Experimental Parasitology, 1954Abstract 1. 1. The rate of oxygen consumption of T. congolense is nearly as high as that of the trypanosomes of the evansi-brucei groups, but its rate of glucose consumption is lower. 2. 2. The R.Q. is high. 3. 3. The main metabolic end products, accounting nearly quantitatively for the degraded glucose, are acetic acid, pyruvic acid,
M, AGOSIN, T, VON BRAND
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An extravascular site of development of Trypanosoma congolense
Nature, 1978TSETSE-TRANSMITTED African pathogenic trypanosomes are thought to be divisible into two groups because of their distribution in the mammalian host and the characteristic lesions they produce during infection1. Trypanosoma brucei brucei and related subspecies have a wide distribution in the body, parasitising the intercellular fluids, connective tissue ...
A G, Luckins, A R, Gray
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The generation and identification of the hemolysin of Trypanosoma congolense
Experientia, 1977The hemolytic activity of Trypanosoma congolense appears to be due to the presence of free fatty acids generated by the action of phospholipase A on endogenous phosphatidyl choline. Some lysolecithin also contributes to the lytic activity. Trypanosoma lewisi, being devoid of phospholipase A, does not generate free fatty acids and is therefore non ...
I R, Tizard +3 more
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Trypanosoma congolense infection in two dogs
Journal of Small Animal Practice, 1995ABSTRACTTrypanosomiasis, caused by Trypanosoma congolense, was diagnosed for the first time in Israel in two boxer dogs imported from Kenya. The dogs developed clinical signs two days after arrival and succumbed to the disease within four days. The major clinical and clinicopathological findings included anaemia, haemorrhages, lymphadenomegaly ...
S, Harrus +3 more
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Effect of isometamidium on Trypanosoma congolense infectivity
Veterinary Parasitology, 1991Isometamidium chloride (Samorin, RMB, England) is a widely used and highly effective trypanocide for the treatment of bovine trypanosomiases. However, the appearance of isometamidium-resistant populations of T. congolense in Africa makes it necessary to develop methods for the rapid and reliable detection of drug resistance in the laboratory. Currently
I A, Sutherland, A, Mounsey, P H, Holmes
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Trypanosoma congolense: Calf erythrocyte survival
Experimental Parasitology, 1979Abstract Hereford calves infected with Trypanosoma congolense developed an anemia which was most severe 10 weeks after infection when packed cell volumes (PCV) averaged 21.1 ± 2.5% (±2 SE) as compared to 33.1 ± 2.1% for controls. At the termination of the study, at 28 weeks postinfection PCVs of infected animals had risen to 27.5 ± 1.0% as compared ...
J M, Preston, B T, Wellde, R M, Kovatch
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Expression of foreign proteins in Trypanosoma congolense
Molecular and Biochemical Parasitology, 1999An expression vector was constructed to express foreign genes in Trypanosoma congolense. The foreign gene and a neomycin phosphotransferase (NPT) gene are flanked by glutamate and alanine rich protein (GARP) gene processing signals and their expression is driven by a ribosomal RNA gene promoter.
N, Downey, J E, Donelson
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Nuclear DNA content of "Trypanosoma congolense"
Acta tropica, 1988We have measured the nuclear DNA content of the major life cycle stages of Trypanosoma congolense, in two clones of geographically distant origin. We find that nuclear DNA content in epimastigote, mammalian blood-stream and metacyclic forms is constant and that the nuclear DNA contents of the two clones were 0.1 pg and 0.09 pg, respectively.
J, Sternberg, C A, Ross, A, Tait
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Congenital transmission of Trypanosoma congolense in mice
Journal of Comparative Pathology, 1983Pregnant mice were infected with a strain of T. congolense which produces a chronic infection, to determine if congenital infection can occur. Some of the mice were killed before delivery and tissues of foetuses injected into clean male mice. Other mothers were allowed to deliver and the tissues of some of the 1-day-old young inoculated into male mice ...
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