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Nasal vaccination against <i>Trypanosoma cruzi</i>: a dual approach for prevention and treatment of chronic Chagas cardiomyopathy. [PDF]

open access: yesFront Immunol
Cacik P   +10 more
europepmc   +1 more source

Peroxynitrite detoxification by Trypanosoma cruzi heme peroxidase supports parasite survival in macrophages. [PDF]

open access: yesJ Biol Chem
Skafar V   +6 more
europepmc   +1 more source

Cardiac alterations induced by Trypanosoma cruzi extracellular vesicles and immune complexes. [PDF]

open access: yesPLoS Negl Trop Dis
Cornet-Gomez A   +5 more
europepmc   +1 more source
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TRYPANOSOMA CRUZI: CONSIDERAÇÕES

2022
A doença de Chagas, causada pelo protozoário Trypanosoma cruzi, é uma enfermidade tipicamente tropical e amplamente dispersa no continente americano, representando um desafio para a saúde pública na América Latina. No Brasil, apenas o benzonidazol está disponível para o tratamento da afecção e este, além de apresentar eficácia limitada na fase crônica,
P.F. Massini, S.M. Araújo
openaire   +1 more source

Characterization of Trypanosoma cruzi telomerase

Acta Tropica, 2011
High telomerase activity is always associated with actively dividing cells, however the detection of this activity in dividing Leishmania and Trypanosoma cruzi cells has always been disappointingly low. Recently, we have found that Leishmania major telomerase activity can be activated by heat, which combined with dilutions of the nuclear extracts ...
Riward, Campelo   +2 more
openaire   +2 more sources

Struvite Precipitation by Trypanosoma cruzi

The Journal of Parasitology, 1987
It has been previously reported that some microorganisms in culture possess the capacity to generate exocellular mineral crystals. Some species of bacteria are able to produce crystals such as aragonite, calcite, apatite, stroncianite, and struvite (Greenfield, 1963, Annals of the New York Academy of Science 109: 23-45; Ennever et al., 1974, Journal of
F J, Adroher, A, Osuna
openaire   +2 more sources

Nucleologenesis inTrypanosoma cruzi

Microscopy and Microanalysis, 2016
AbstractNucleolar assembly is a cellular event that requires the synthesis and processing of ribosomal RNA, in addition to the participation of pre-nucleolar bodies (PNBs) at the end of mitosis. In mammals and plants, nucleolar biogenesis has been described in detail, but in unicellular eukaryotes it is a poorly understood process.
Tomás, Nepomuceno-Mejía   +4 more
openaire   +2 more sources

Trypanosoma cruzi: Surface antigenic determinants

Zeitschrift f�r Parasitenkunde Parasitology Research, 1983
A fraction (FAd) capable of inhibiting specific agglutination reactions of anti-epimastigote sera (anti-LE) was obtained by extracting the sediment of lyophilized epimastigote lysates (LE) with 0.05 M phosphate buffered saline, at 37 degrees C for 1 h.
W M, Tamashiro   +6 more
openaire   +2 more sources

Heme synthetase in Trypanosoma cruzi

Comparative Biochemistry and Physiology Part B: Comparative Biochemistry, 1986
Heme-synthetase (Heme-S) has been studied in the epimastigote form of T. cruzi (Tulahuen and Y strains). The enzyme is confined to the "mitochondrial" fraction (sedimented at 30,000 g). Activity was dependent on protein and time of cell storage. Enzymic proto- and meso-heme formation was inhibited up to 40 and 72% respectively by Triton X-100.
T A, Salzman, A M, Batlle
openaire   +2 more sources

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