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Nasal vaccination against <i>Trypanosoma cruzi</i>: a dual approach for prevention and treatment of chronic Chagas cardiomyopathy. [PDF]
Cacik P +10 more
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Peroxynitrite detoxification by Trypanosoma cruzi heme peroxidase supports parasite survival in macrophages. [PDF]
Skafar V +6 more
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Cardiac alterations induced by Trypanosoma cruzi extracellular vesicles and immune complexes. [PDF]
Cornet-Gomez A +5 more
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TRYPANOSOMA CRUZI: CONSIDERAÇÕES
2022A doença de Chagas, causada pelo protozoário Trypanosoma cruzi, é uma enfermidade tipicamente tropical e amplamente dispersa no continente americano, representando um desafio para a saúde pública na América Latina. No Brasil, apenas o benzonidazol está disponível para o tratamento da afecção e este, além de apresentar eficácia limitada na fase crônica,
P.F. Massini, S.M. Araújo
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Characterization of Trypanosoma cruzi telomerase
Acta Tropica, 2011High telomerase activity is always associated with actively dividing cells, however the detection of this activity in dividing Leishmania and Trypanosoma cruzi cells has always been disappointingly low. Recently, we have found that Leishmania major telomerase activity can be activated by heat, which combined with dilutions of the nuclear extracts ...
Riward, Campelo +2 more
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Struvite Precipitation by Trypanosoma cruzi
The Journal of Parasitology, 1987It has been previously reported that some microorganisms in culture possess the capacity to generate exocellular mineral crystals. Some species of bacteria are able to produce crystals such as aragonite, calcite, apatite, stroncianite, and struvite (Greenfield, 1963, Annals of the New York Academy of Science 109: 23-45; Ennever et al., 1974, Journal of
F J, Adroher, A, Osuna
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Nucleologenesis inTrypanosoma cruzi
Microscopy and Microanalysis, 2016AbstractNucleolar assembly is a cellular event that requires the synthesis and processing of ribosomal RNA, in addition to the participation of pre-nucleolar bodies (PNBs) at the end of mitosis. In mammals and plants, nucleolar biogenesis has been described in detail, but in unicellular eukaryotes it is a poorly understood process.
Tomás, Nepomuceno-Mejía +4 more
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Trypanosoma cruzi: Surface antigenic determinants
Zeitschrift f�r Parasitenkunde Parasitology Research, 1983A fraction (FAd) capable of inhibiting specific agglutination reactions of anti-epimastigote sera (anti-LE) was obtained by extracting the sediment of lyophilized epimastigote lysates (LE) with 0.05 M phosphate buffered saline, at 37 degrees C for 1 h.
W M, Tamashiro +6 more
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Heme synthetase in Trypanosoma cruzi
Comparative Biochemistry and Physiology Part B: Comparative Biochemistry, 1986Heme-synthetase (Heme-S) has been studied in the epimastigote form of T. cruzi (Tulahuen and Y strains). The enzyme is confined to the "mitochondrial" fraction (sedimented at 30,000 g). Activity was dependent on protein and time of cell storage. Enzymic proto- and meso-heme formation was inhibited up to 40 and 72% respectively by Triton X-100.
T A, Salzman, A M, Batlle
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