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Nucleologenesis inTrypanosoma cruzi

Microscopy and Microanalysis, 2016
AbstractNucleolar assembly is a cellular event that requires the synthesis and processing of ribosomal RNA, in addition to the participation of pre-nucleolar bodies (PNBs) at the end of mitosis. In mammals and plants, nucleolar biogenesis has been described in detail, but in unicellular eukaryotes it is a poorly understood process.
Tomás, Nepomuceno-Mejía   +4 more
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Trypanosoma cruzi: Surface antigenic determinants

Zeitschrift f�r Parasitenkunde Parasitology Research, 1983
A fraction (FAd) capable of inhibiting specific agglutination reactions of anti-epimastigote sera (anti-LE) was obtained by extracting the sediment of lyophilized epimastigote lysates (LE) with 0.05 M phosphate buffered saline, at 37 degrees C for 1 h.
W M, Tamashiro   +6 more
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Heme synthetase in Trypanosoma cruzi

Comparative Biochemistry and Physiology Part B: Comparative Biochemistry, 1986
Heme-synthetase (Heme-S) has been studied in the epimastigote form of T. cruzi (Tulahuen and Y strains). The enzyme is confined to the "mitochondrial" fraction (sedimented at 30,000 g). Activity was dependent on protein and time of cell storage. Enzymic proto- and meso-heme formation was inhibited up to 40 and 72% respectively by Triton X-100.
T A, Salzman, A M, Batlle
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Catabolic metabolism in Trypanosoma cruzi

International Journal for Parasitology, 1980
Abstract Culture, blood and intracellular forms of Trypanosoma cruzi have a high rate of endogenous oxygen uptake and probably utilize amino acids and carbohydrates as their exogenous energy sources. It is likely that triglyceride is the main energy reserve. Oxidation of carbohydrate by all forms is probably via a glycolytic sequence and a complete
G W, Rogerson, W E, Gutteridge
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Immunity to Trypanosoma cruzi

1980
Publisher Summary Trypanosoma cruzi (T. cruzi), the causative agent of Chagas disease, is a digenetic trypanosomatid, which circulates in the bloodstream of the vertebrate host as trypomastigotes and has an obligatory intracellular phase in which the parasite multiplies as amastigotes, which differentiate into trypomastigotes.
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Intermediary metabolism of Trypanosoma cruzi

Parasitology Today, 1994
In this article, Julio Urbino discusses the characteristics o f the intermediary metabolism of Trypanosoma cruzi (the causative agent of Chagas disease), which are responsible for the unusual capacity of this parasite to use carbohydrates or amino acids as carbon and energy sources without drastic changes in its catabolic enzyme levels(1-3).
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The Trypanosoma cruzi Proteome

Science, 2005
To complement the sequencing of the three kinetoplastid genomes reported in this issue, we have undertaken a whole-organism, proteomic analysis of the four life-cycle stages of Trypanosoma cruzi . Peptides mapping to 2784 proteins in 1168 protein groups from the annotated T. cruzi genome were
J A, Atwood   +7 more
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Purine metabolism in Trypanosoma cruzi

Molecular and Biochemical Parasitology, 1981
Culture forms of Trypanosoma cruzi are incapable of synthesizing purines de novo from formate, glycine, or serine and require an exogenous purine for growth. Adenine, hypoxanthine, guanine, xanthine and their respective ribonucleosides are equal in their abilities to support growth.
R L, Berens   +3 more
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Immunotherapy of Trypanosoma Cruzi Infections

Current Drug Target - Immune, Endocrine & Metabolic disorders, 2002
The protozoan parasite Trypanosoma cruzi, causative agent of Chagas' disease, is transmitted to man and other mammals by triatominae insects, or 'kissing bugs'. Since its discovery in 1909, by Carlos Chagas, this parasite has been the object of several publications in the domains of immunology, cellular biology and of control gene organization ...
Chamond, Nathalie   +2 more
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Fatty acids of Trypanosoma cruzi

Comparative Biochemistry and Physiology Part B: Comparative Biochemistry, 1982
1. The fatty acid pattern of total lipids from T. cruzi is different from one of its growth medium. 2. The distribution of major fatty acids in phospholipid fraction was linoleic (50.4%), oleic (25.6%), stearic (10.1%) and palmitic (6.3%) and in neutral lipid fraction oleic and linolelc (about 29% each), palmitic (18.3%) and stearic (9.8%). 3.
S L, Timm   +2 more
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