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Experimental Trypanosoma cruzi infection cured with a mechanistically distinct drug combination
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The Development of Trypanosoma cruzi in Triatominae
Parasitology Today, 2000Trypanosoma cruzi multiplies and differentiates in the digestive tract of triatomine insects. These insects ingest an enormous amount of blood, with ingestion followed very rapidly by a strong diuresis, slow digestion and occasionally long periods of starvation.
G A Schaub, A H Kollien
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Struvite Precipitation by Trypanosoma cruzi
The Journal of Parasitology, 1987It has been previously reported that some microorganisms in culture possess the capacity to generate exocellular mineral crystals. Some species of bacteria are able to produce crystals such as aragonite, calcite, apatite, stroncianite, and struvite (Greenfield, 1963, Annals of the New York Academy of Science 109: 23-45; Ennever et al., 1974, Journal of
F J, Adroher, A, Osuna
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Nucleologenesis inTrypanosoma cruzi
Microscopy and Microanalysis, 2016AbstractNucleolar assembly is a cellular event that requires the synthesis and processing of ribosomal RNA, in addition to the participation of pre-nucleolar bodies (PNBs) at the end of mitosis. In mammals and plants, nucleolar biogenesis has been described in detail, but in unicellular eukaryotes it is a poorly understood process.
Tomás, Nepomuceno-Mejía +4 more
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Catabolic metabolism in Trypanosoma cruzi
International Journal for Parasitology, 1980Abstract Culture, blood and intracellular forms of Trypanosoma cruzi have a high rate of endogenous oxygen uptake and probably utilize amino acids and carbohydrates as their exogenous energy sources. It is likely that triglyceride is the main energy reserve. Oxidation of carbohydrate by all forms is probably via a glycolytic sequence and a complete
G W, Rogerson, W E, Gutteridge
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1980
Publisher Summary Trypanosoma cruzi (T. cruzi), the causative agent of Chagas disease, is a digenetic trypanosomatid, which circulates in the bloodstream of the vertebrate host as trypomastigotes and has an obligatory intracellular phase in which the parasite multiplies as amastigotes, which differentiate into trypomastigotes.
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Publisher Summary Trypanosoma cruzi (T. cruzi), the causative agent of Chagas disease, is a digenetic trypanosomatid, which circulates in the bloodstream of the vertebrate host as trypomastigotes and has an obligatory intracellular phase in which the parasite multiplies as amastigotes, which differentiate into trypomastigotes.
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Characterization of Trypanosoma cruzi telomerase
Acta Tropica, 2011High telomerase activity is always associated with actively dividing cells, however the detection of this activity in dividing Leishmania and Trypanosoma cruzi cells has always been disappointingly low. Recently, we have found that Leishmania major telomerase activity can be activated by heat, which combined with dilutions of the nuclear extracts ...
Riward, Campelo +2 more
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Fatty acids of Trypanosoma cruzi
Comparative Biochemistry and Physiology Part B: Comparative Biochemistry, 19821. The fatty acid pattern of total lipids from T. cruzi is different from one of its growth medium. 2. The distribution of major fatty acids in phospholipid fraction was linoleic (50.4%), oleic (25.6%), stearic (10.1%) and palmitic (6.3%) and in neutral lipid fraction oleic and linolelc (about 29% each), palmitic (18.3%) and stearic (9.8%). 3.
S L, Timm +2 more
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Purine metabolism in Trypanosoma cruzi
Molecular and Biochemical Parasitology, 1981Culture forms of Trypanosoma cruzi are incapable of synthesizing purines de novo from formate, glycine, or serine and require an exogenous purine for growth. Adenine, hypoxanthine, guanine, xanthine and their respective ribonucleosides are equal in their abilities to support growth.
R L, Berens +3 more
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On the chromatin structure of Trypanosoma cruzi
Molecular and Biochemical Parasitology, 1980The chromatin structure of Trypanosoma cruzi was investigated. It was found that, as in other eukaryotes, the chromatin is organized in repeating units, the nucleosomes containing about 200 base pairs of DNA associated with histones. While there is no difference in the DNA size in nucleosomes from T.
S, Astolfi Filho +2 more
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