Results 71 to 80 of about 88,689 (264)

Genome-wide analysis of 30 -untranslated regions supports the existence of post-transcriptional regulons controlling gene expression in trypanosomes [PDF]

, 2013
In eukaryotic cells, a group of messenger ribonucleic acids (mRNAs) encoding functionally interrelated proteins together with the trans-acting factors that coordinately modulate their expression is termed a post-transcriptional regulon, due to their ...
Agüero, Fernan Gonzalo, Carmona, Santiago Javier, de Gaudenzi, Javier Gerardo, Frasch, Alberto Carlos C.   +3 more
core   +3 more sources

Evaluation of two candidate molecules—TCTP and cecropin—on the establishment of Trypanosoma brucei gambiense into the gut of Glossina palpalis gambiensis

Insect Science, EarlyView.
This study investigates the potential of enhancing the resistance of Glossina palpalis gambiensis to Trypanosoma brucei gambiense to mitigate the transmission of Human African Trypanosomiasis. We successfully cloned genes encoding proteins of interest in Sodalis strains, resulting in recombinant Sodalis (recSodalis) that were micro‐injected into the L3
François Sougal Ngambia Freitas, Linda De Vooght, Flobert Njiokou, Jan Van Den Abeele, Géraldine Bossard, Bernadette Tchicaya, Rosa Milagros Corrales, Sophie Ravel, Anne Geiger, David Berthier‐Teyssedre   +9 more
wiley   +1 more source

Molecular characterization of Trypanosoma cruzi Mexican strains and their behavior in the mouse experimental model

Revista da Sociedade Brasileira de Medicina Tropical, 2011
INTRODUCTION: For a long time, the importance of Chagas disease in Mexico, where many regarded it as an exotic malady, was questioned. Considering the great genetic diversity among isolates of Trypanosoma cruzi, the importance of this biological ...
César Gómez-Hernández, Karine Rezende-Oliveira, Gabriel Antônio Nogueira Nascentes, Lara Rocha Batista, Henrique Borges Kappel, José Alejandro Martinez-Ibarra, Francisco Trujillo Contreras, Eliane Lages-Silva, Luis Eduardo Ramírez   +8 more
doaj   +1 more source

Repurposing of terconazole as an anti Trypanosoma cruzi agent [PDF]

, 2019
Trypanosoma cruzi is the causative agent of Chagas disease, a parasitic infection endemic in Latin America. Currently there are no effective treatments for the chronic phase of the disease, when most patients are diagnosed, therefore the development of ...
Martínez Sayé, Melisa Soledad, Miranda, Mariana Reneé, Pereira, Claudio Alejandro, Reigada, Chantal, Valera Vera, Edward Augusto   +4 more
core   +1 more source

Dual Role of Natural Killer Cells in Early Pregnancy: Immunopathological Implications and Therapeutic Potential in Recurrent Spontaneous Abortion and Recurrent Implantation Failure

Cell Proliferation, EarlyView.
This article elaborates on the role of NK cells in early pregnancy from multiple perspectives, including molecular mechanisms and therapeutic interventions. It also discusses how NK cell dysfunction contributes to RSA and RIF, aiming to provide insights for future research on NK cell mechanisms and clinical treatment of RSA and RIF.
Defeng Guan, Zhou Chen, Yuhua Zhang, Wenjie Sun, Lifei Li, Xia Huang   +5 more
wiley   +1 more source

Busca retrospectiva da transmissão maternal da infecção chagásica em pacientes na fase crônica A retrospective search for maternal transmission of Chagas infection from patients in the chronic phase

Revista da Sociedade Brasileira de Medicina Tropical, 2004
Avaliamos a transmissão maternal do Trypanosoma cruzi em 278 filhos de 145 mães com a doença crônica causada por esse protozoário, nascidos após o estabelecimento do diagnóstico materno.
Anis Rassi, Vicente Amato Neto, Gustavo Gabriel Rassi, Valdir Sabbaga Amato, Anis Rassi Júnior, Alejandro O. Luquetti, Sérgio Gabriel Rassi   +6 more
doaj   +1 more source

Linajes de Trypanosoma cruzi en pacientes con enfermedad de Chagas y coinfección por VIH [PDF]

, 2009
Introducción. Las poblaciones naturales de T. cruzi han sido clasificadas en seis linajes filogenéticos o unidades de tipificación discreta: T. cruzi I, IIa, IIb, IIc, IId y IIe, que pueden jugar un rol en el tropismo tisular y patogénesis de la ...
Altcheh, Jaime Marcelo, Begher, Sandra, Bisio, Margarita María Catalina, Burgos, Juan Miguel, Cura, Carolina Inés, Duffy, Tomás, Freilij, Hector León, Giganti, Salvador Óscar, Levin, Mariano Jorge, Scapellato, Pablo Gustavo, Schijman, Alejandro Gabriel, Schreck, Ricardo   +11 more
core  

Chronic Trypanosoma cruzi infection potentiates adipose tissue macrophage polarization toward an anti-inflammatory M2 phenotype and contributes to diabetes progression in a diet-induced obesity model [PDF]

, 2016
Chronic obesity and Chagas disease (caused by the protozoan Trypanosoma cruzi) represent serious public health concerns. The interrelation between parasite infection, adipose tissue, immune system and metabolism in an obesogenic context, has not been ...
Andrada, Marta Cecilia, Aoki, Maria del Pilar, Cabalén, María Eugenia, Cabral, Maria Fernanda, Cano, Roxana Carolina, Gea, Susana, Onofrio, Luisina Inés, Ponce, Nicolás Eric, Sanmarco, Liliana Maria   +8 more
core   +4 more sources

A new piece in the repeatome puzzle of Triatominae bugs: The analysis of Triatoma rubrofasciata reveals the role of satellite DNAs in the karyotypic evolution of distinct lineages

Insect Molecular Biology, EarlyView.
Satellite DNAs comprise the major component of the Triatoma rubrofasciata repeatome, highlighting their central role in genome composition and architecture. Satellite DNA families show recent amplification in heterochromatin and older, more divergent satellite DNAs located in euchromatin, indicating distinct evolutionary histories.
Sebastián Pita, Pablo Mora, José M. Rico‐Porras, Diogo C. Cabral‐de‐Mello, Francisco J. Ruiz‐Ruano, Teresa Palomeque, Ho Viet Hieu, Francisco Panzera, Pedro Lorite   +8 more
wiley   +1 more source

Novo encontro do Trypanosoma (Megatrypanum) freitasi, parasita do gambá A new finding of Trypanosoma (Megatrypanum) freitasi, parasite of the opossum

Revista de Saúde Pública, 1976
Relata-se um novo encontro do Trypanosoma (Megatrypanum) freitasi, raro tripanosomatídeo encontrado no sangue de marsupiais, do gênero Didelphis.
Eduardo Olavo da Rocha e Silva, Dino Baptista Germano Pattoli, José de Campos Camargo   +2 more
doaj   +1 more source