Results 51 to 60 of about 50,549 (209)

Tracking autophagy during proliferation and differentiation of Trypanosoma brucei [PDF]

, 2014
Autophagy is a lysosome-dependent degradation mechanism that sequesters target cargo into autophagosomal vesicles. The Trypanosoma brucei genome contains apparent orthologues of several autophagy-related proteins including an ATG8 family. These ubiquitin-
Mottram, Jeremy, Jones, N.G., Coombs, Graham, Proto, William R   +3 more
core   +2 more sources

Loop-mediated isothermal amplification (LAMP) test for detection of Trypanosoma evansi strain B [PDF]

, 2010
Camel Trypanosomiasis (Surra) is mainly caused by Trypanosoma evansi strains that express variable surface glycoprotein (VSG) RoTat 1.2 However, in Kenya a second causative strain that does not express RoTat 1.2 VSG (T. evansi type B) has been identified.
Njiru, Z.K., Enyaru, J.C., Dargantes, A.P., Ouma, J.O.   +3 more
core  

Synthesis, Electrochemistry, In Vitro Antiprotozoal Efficacy and Mechanistic Study of Novel ‘Ferrantoin’ and Related Derivatives

Applied Organometallic Chemistry, Volume 40, Issue 7, July 2026.
1,2‐Disubstituted ferrocene analogues bearing hydantoin or rhodanine synthons were synthesised and assessed for antitrypanosomatid activity. An antileishmanial early lead, analogue 23, acting through ROS generation and hence oxidative stress, was uncovered.
Maryna Saayman, Janine Aucamp, Helena D. Janse van Rensburg, Christina Kannigadu, Rotondwa Mphephu, Andrew J. Swarts, Keisuke Suganuma, David D. N'Da   +7 more
wiley   +1 more source

Molecular diagnosis of acute and chronic infection of Trypanosoma evansi in experimental male and female mice

Onderstepoort Journal of Veterinary Research, 2019
Trypanosoma evansi is enzootic in camels in Egypt, and water buffaloes act as a reservoir for camel infection. Molecular techniques have contributed towards understanding the epidemiology of T. evansi. Trypanosoma evansi was detected in acute and chronic
Tahani S. Behour, Shawky M. Aboelhadid, Wahid M. Mousa, Adel S. Amin, Saeed A. El-Ashram   +4 more
doaj   +1 more source

Development of tools to improve the detection of Trypanosoma evansi in Australia [PDF]

, 2009
The aim of this study was to evaluate new methods to improve detection and investigation of the effects of chronic or subclinical infection with Trypanosoma evansi in various mammalian species.
Smuts, Celia
core  

In Vitro Antitrypanosomal and Antibacterial Activity of Aqueous, Hydroethanolic and Ethanolic Extracts of Rumex obtusifolius L. Leaf and Root

Basic &Clinical Pharmacology &Toxicology, Volume 138, Issue 5, May 2026.
ABSTRACT Plant extracts are an important raw material for the development of new drugs. Rumex obtusifolius L., popularly known as ‘bitter dock’, has significant pharmacological properties. This study evaluated the in vitro antitrypanosomal activity of aqueous, hydroethanolic and ethanolic extracts from the leaf and roots of R. obtusifolius L.
Gabriela K. Borges, Gabriella B. Das Neves, Letícia Reichardt, Ubirajara Maciel da Costa, Luiz C. Miletti, Amanda L. Bastos‐Pereira   +5 more
wiley   +1 more source

Potential entry pathways for 25 vector‐borne disease agents

EFSA Journal, Volume 24, Issue 5, May 2026.
Abstract This Scientific Report identifies the potential entry pathways for 25 selected vector‐borne diseases (VBDs) into currently free EU Member States. The diseases comprise 12 listed under the Animal Health Law (AHL) and 13 non‐listed diseases, selected using predefined eligibility criteria.
European Food Safety Authority (EFSA), Sofie Dhollander, Ieva Baltusyte, Fabio Bigoni, Alessandro Broglia, Jordi Figuerola, Hans‐Hermann Thulke, Miguel Angel Chueca Miranda   +7 more
wiley   +1 more source

Knowledge mapping of risk mitigation measures against vector‐borne diseases

EFSA Journal, Volume 24, Issue 5, May 2026.
Abstract A comprehensive synthesis of current evidence on surveillance, prevention and control measures for 25 selected vector‐borne diseases (VBDs) affecting animals in the EU is presented here. The assessment integrates evidence from systematic literature reviews, modelling studies, field investigations and expert judgement.
European Food Safety Authority (EFSA), Ieva Baltusyte, Fabio Bigoni, Alessandro Broglia, Sofie Dhollander, Stefania Tampach, Jordi Figuerola, Hans Hermann Thulke, Miguel Ángel Chueca Miranda   +8 more
wiley   +1 more source

Identification and mapping of potential and highly likely vectors for selected vector‐borne diseases in the EU and neighbouring countries

EFSA Journal, Volume 24, Issue 5, May 2026.
Abstract This report addresses Term of Reference 1.2 by providing a comprehensive knowledge‐mapping of arthropod vector species competent to transmit selected vector‐borne diseases (VBDs) including VBDs listed under Regulation (EU) 2016/429 and Regulation (EU) 2020/687, as well as additional non‐listed pathogens with potential epidemiological relevance.
European Food Safety Authority (EFSA), Sofie Dhollander, Ieva Baltusyte, Fabio Bigoni, Alessandro Broglia, Jordi Figuerola, Hans‐Hermann Thulke, Miguel Angel Chueca Miranda   +7 more
wiley   +1 more source

Characterization of Trypanosoma evansi type B

Infection, Genetics and Evolution, 2006
A distinctive feature of Trypanosoma evansi is the possession of a kinetoplast that contains homogeneous DNA minicircles, but lacks DNA maxicircles. Two major sequence variants of the minicircle have been described and here we have sequenced the type B variant and designed a specific PCR test to distinguish it from type A.
Njiru, Z., Constantine, C., Masiga, D., Reid, S.A., Thompson, R.C.A., Gibson, W.   +5 more
openaire   +5 more sources