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Chagas’ disease is a neglected tropical disease caused by Trypanosoma cruzi which is endemic throughout Latin America and is spread by worldwide migration. Diagnosis is currently limited to serological and molecular techniques having variations regarding their sensitivity and specificity.
Diego Ordóñez +11 more
wiley +1 more source
In this study the effect of eight DNA topoisomerase inhibitors on the growth Trypanosoma rangeli epimastigotes in cell culture was investigated. Among the eight compounds tested, idarubicin was the only compound that displayed promising trypanocidal ...
Momodou Jobe +14 more
doaj +1 more source
Trypanosoma rangeli is a non-virulent hemoflagellate parasite infecting humans, wild and domestic mammals in Central and Latin America. The share of genotypic, phenotypic, and biological similarities with the virulent, human-infective T.
C. L. Mansur Pontes +6 more
semanticscholar +1 more source
Trypanosoma rangeli and Trypanosoma cruzi: cross-reaction among their immunogenic components [PDF]
It has been demonstrated that immuno-modu-lating mechanisms induced by epimastigotes ofTrypanosoma rangeli, an assumed harmless hu-man parasite, may have relevance to protectionagainst Trypanosoma cruzi, the causative organ-ism of Chagas’ disease (B Basso et al. 1991 Am JTrop Med Hyg 44: 413-419).
A. Saldaña, O. E. Sousa
openaire +4 more sources
Chagas disease is a neglected tropical disease caused by the parasite Trypanosoma cruzi. Despite the efforts and distinct methodologies, the search of antigens for diagnosis, vaccine, and drug targets for the disease is still needed. The present study is aimed at identifying possible antigens that could be used for diagnosis, vaccine, and drugs targets
Rafael Obata Trevisan +17 more
wiley +1 more source
The morphological sequence of Trypanosoma rangeli development in the alimentary canal of Rhodnius prolixus, is described, with observation made in dissected guts from 6 hours to 45 days post-infection.
N. Añez
doaj +1 more source
In our laboratory, we have developed a model of vaccination in mice with Trypanosoma rangeli, a non-pathogenic parasite that shares many antigens with Trypanosoma cruzi. The vaccinated mice were protected against infection with virulent T. cruzi.
Beatriz Basso +2 more
doaj +1 more source
Karyotype variability in Trypanosoma rangeli
SUMMARYThe molecular karyotypes of several different protozoan parasites show high intra-species variation, including different kinetoplastids such as Trypanosoma brucei, Trypanosoma cruzi and Leishmania ssp. In this study, the molecular karyotype of Trypanosoma rangeli was examined.
Henriksson, J. +4 more
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La región intergénica del gen H2A apoya las subpoblaciones KP1(-) y KP1(+) de Trypanosoma rangeli
Introducción. Con base en la amplificación del ADN de los minicírculos del cinetoplasto y de los genes miniexón, Trypanosoma rangeli ha sido clasificado en las subpoblaciones KP1(-) y KP1(+). Objetivo.
Brian Alejandro Suárez +2 more
doaj +1 more source
Salivaria or Stercoraria? The Trypanosoma rangelidilemma [PDF]
The taxonomic status of Trypanosoma rangeli as well as the tools for its molecular characterization is briefly commented.
openaire +2 more sources

