Results 91 to 100 of about 39,396 (251)

Telomere conversion in trypanosomes

open access: yesNucleic Acids Research, 1983
Activation of the gene coding for variant surface glycoprotein (VSG) 118 in Trypanosoma brucei proceeds via a duplicative transposition to a telomeric expression site. The resulting active expression-linked extra copy (ELC) is usually flanked by DNA that lacks sites for most restriction enzymes and that is thought to interfere with the cloning of the ...
Titia de Lange   +3 more
openaire   +4 more sources

The Constructive Neutral Evolution of Behaviour

open access: yesEcology and Evolution, Volume 15, Issue 7, July 2025.
We explain how constructive neutral evolution (CNE) can lead to the evolution of nonfunctional behavioural complexity, highlighting a mechanism that is unknown to behavioural ecologists despite being frequently considered by molecular biologists. We summarise indirect evidence that suggests behavioural CNE has occurred and outline how the hypothesis ...
Andrew M. Catherall‐Ostler   +1 more
wiley   +1 more source

Nutritional Potential and Protective Effects of Colocassia esculenta Flowers Against 2,4‐Dinitrophenyl Hydrazine (DNPH) Induced Anemia Wistar Strain Rats

open access: yesFood Science &Nutrition, Volume 13, Issue 6, June 2025.
The nutritional properties of C. esculenta have been demonstrated. Consumption of C. esculenta reduces anemic disorder in Wistar rats. C. esclenta harvested in Dschang has the best anti‐anemic potential. ABSTRACT This study aimed to assess the nutritional value and effect of Colocasia esculenta flowers on induced anemia in Wistar rats.
Josée Rebecca Nombo   +6 more
wiley   +1 more source

Effectiveness of a 10-day melarsoprol schedule for the treatment of late-stage human African trypanosomiasis: confirmation from a multinational study (IMPAMEL II). [PDF]

open access: yes, 2005
BACKGROUND: Treatment of late-stage human African trypanosomiasis (HAT) with melarsoprol can be improved by shortening the regimen. A previous trial demonstrated the safety and efficacy of a 10-day treatment schedule.
Asumu, P   +10 more
core   +2 more sources

Protrusion‐Derived Extracellular Vesicles (PD‐EVs) and Their Diverse Origins: Key Players in Cellular Communication, Cancer Progression, and T Cell Modulation

open access: yesBiology of the Cell, Volume 117, Issue 6, June 2025.
Protrusion‐derived extracellular vesicles (PD‐EVs) driving tumor progression and immune modulation. PD‐EVs arise from dynamic cellular extensions and serve as powerful communication tools. In cancer, they reshape the tumor microenvironment, promote angiogenesis and metastasis, and modulate immune responses, including T cell activation.
Mireia Gomez Duro   +4 more
wiley   +1 more source

A multigene family encoding surface glycoproteins in Trypanosoma congolense

open access: yesMicrobial Cell, 2017
Trypanosoma congolense, the causative agent of the most important livestock disease in Africa, expresses specific surface proteins involved in its parasitic lifestyle. Unfortunately, the complete repertoire of such molecules is far from being deciphered.
Magali Thonnus   +2 more
doaj   +1 more source

Delineating neuroinflammation, parasite CNS invasion, and blood-brain barrier dysfunction in an experimental murine model of human African trypanosomiasis [PDF]

open access: yes, 2017
Although Trypanosoma brucei spp. was first detected by Aldo Castellani in CSF samples taken from sleeping sickness patients over a century ago there is still a great deal of debate surrounding the timing, route and effects of transmigration of the ...
Bradley, Barbara   +2 more
core   +1 more source

VSIG4‐Expressing Macrophages Contribute to Antiparasitic and Antimetastatic Responses in the Peritoneal Cavity

open access: yesEuropean Journal of Immunology, Volume 55, Issue 5, May 2025.
Although VSIG4+ LPMs and VSIG4− LPMs are identical at the transcriptomic and surface proteomic level, VSIG4+ LPMs are superior phagocytes that protect against CRC peritoneal outgrowth and influence the early phase of T. brucei brucei infection. ABSTRACT Large peritoneal macrophages (LPMs) play a role as gatekeepers of peritoneal homeostasis by ...
Els Lebegge   +25 more
wiley   +1 more source

A preliminary serological study of Trypanosoma evansi and Trypanosoma lewisi in a Chinese human population [PDF]

open access: yes, 2018
Trypanosoma evansi, known as an animal trypanosome, is widely distributed in many countries of Africa, Asia and South America; it causes significant economic loss in these countries.
Courtois, Patrick   +8 more
core   +1 more source

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