Results 71 to 80 of about 50,381 (267)
Frontiers in Immunology, 2019 African trypanosomes, such as Trypanosoma brucei (T. brucei), are protozoan parasites of the mammalian vasculature and central nervous system that are best known for causing fatal human sleeping sickness.
Nicole K. Campbell +7 more
doaj +1 more source
Facilitating trypanosome imaging
Experimental Parasitology, 2017 Research on trypanosomes as a model organism has provided a substantial contribution to a detailed understanding of basic cellular processes within the last few years. At the same time, major advances in super-resolution microscopy have been achieved, facilitating the resolution of biological structures in living cells at a scale of a few nm.
Glogger, Marius +6 more
openaire +2 more sources
Basic &Clinical Pharmacology &Toxicology, Volume 138, Issue 5, May 2026.ABSTRACT Plant extracts are an important raw material for the development of new drugs. Rumex obtusifolius L., popularly known as ‘bitter dock’, has significant pharmacological properties. This study evaluated the in vitro antitrypanosomal activity of aqueous, hydroethanolic and ethanolic extracts from the leaf and roots of R. obtusifolius L.
Gabriela K. Borges +5 more
wiley +1 more source
Analysis of the proteome and the secretome of animal trypanosomes : a standardized analytical method to look for new molecular targets [PDF]
, 2007 The causative agents of animal trypanosomosis are various species of protozoan parasites belonging to the genus Trypanosoma, among which T. congolense and T. evansi are the major pathogenic species. The extra cellular position of the trypanosomes implies
Bengaly, Zakaria +10 more
core
Metalloids: Semi as Metals yet Full of Antimicrobial Potential
ChemMedChem, Volume 21, Issue 7, 14 April 2026.Metalloids such as boron (B), silicon (Si), germanium (Ge), arsenic (As), antimony (Sb), and tellurium (Te) bridge metals and non‐metals, displaying unique chemical versatility. Recent research highlights their diverse antimicrobial and therapeutic potentials, from natural products to synthetic organic and organometallic molcules, underscoring renewed ...
Kevin Böhm +2 more
wiley +1 more source
The challenging problem of disease staging in human African trypanosomiasis (sleeping sickness): a new approach to a circular question [PDF]
, 2017 Human African trypanosomiasis (HAT), also known as sleeping sickness, puts millions of people at risk in sub-Saharan Africa and is a neglected parasitic disease that is almost always fatal if untreated or inadequately treated. HAT manifests itself in two
Gettinby, George +2 more
core +1 more source
Cytoskeleton, 2012 AbstractCytokinesis is a crucial step in the cell division cycle whereby the cell membrane and underlying cortex is remodelled and drawn together to create two new daughter cells. While in many eukaryotic systems this process is accomplished by an actomyosin contractile ring, the protozoan parasite Trypanosoma brucei displays an unusual mechanism for ...
Farr, H, Gull, K
openaire +3 more sources
Advanced Intelligent Systems, Volume 8, Issue 4, April 2026.The polymerase chain reaction (PCR).Perturbation Theory and Machine Learning framework integrates perturbation theory and machine learning to classify genetic sequences, distinguishing ancient DNA from modern controls and predicting tree health from soil metagenomic data.
Jose L. Rodriguez +19 more
wiley +1 more source
Selenosugars targeting the infective stage of Trypanosoma brucei with high selectivity
International Journal for Parasitology: Drugs and Drug ResistanceEarlier evidences showed that diglycosyl diselenides are active against the infective stage of African trypanosomes (top hits IC50 0.5 and 1.5 μM) but poorly selective (selectivity index 38-folds vs. murine and human macrohages).
Estefanía Dibello +9 more
doaj +1 more source
Antigenic variation in African trypanosomes
Molecular and biochemical parasitology (Print), 2014 Graphical ...
D. Horn
semanticscholar +1 more source