Results 81 to 90 of about 50,381 (267)

Glycosomal Phosphoenolpyruvate Carboxykinase CRISPR/Cas9‐Deletion and Its Role in Trypanosoma cruzi Metacyclogenesis and Infectivity in Mammalian Host

The FASEB Journal, Volume 40, Issue 6, 31 March 2026.
Effects of PEPCK deficiency in Trypanosoma cruzi bioenergetics and life stages. ABSTRACT Trypanosoma cruzi, the causative agent of Chagas disease, possesses glycosomes—unique organelles that house key metabolic enzymes, several of which are promising therapeutic targets.
Carolina S. D. Vieira, Wei Wang, Fernando Sanchez‐Valdez, Jihyun Lim, Brooke E. White, Camilla G. S. Souza, Rick L. Tarleton, Marcia C. Paes, Natalia P. A. Nogueira   +8 more
wiley   +1 more source

The Spliced Leader RNA Silencing (SLS) Pathway in Trypanosoma brucei Is Induced by Perturbations of Endoplasmic Reticulum, Golgi Complex, or Mitochondrial Protein Factors: Functional Analysis of SLS-Inducing Kinase PK3

mBio, 2021
In the parasite Trypanosoma brucei, the causative agent of human African sleeping sickness, all mRNAs are trans-spliced to generate a common 5′ exon derived from the spliced leader (SL) RNA.
Uthman Okalang, Bar Mualem Bar-Ner, K. Shanmugha Rajan, Nehemya Friedman, Saurav Aryal, Katarina Egarmina, Ronen Hope, Netaly Khazanov, Hanoch Senderowitz, Assaf Alon, Deborah Fass, Shulamit Michaeli   +11 more
doaj   +1 more source

The Trypanosoma brucei AIR9-like protein is cytoskeleton-associated and is required for nucleus positioning and accurate cleavage furrow placement [PDF]

, 2012
AIR9 is a cytoskeleton-associated protein in Arabidopsis thaliana with roles in cytokinesis and cross wall maturation, and reported homologues in land plants and excavate protists, including trypanosomatids.
Almeida Costa, Cristina, Gibson, Wendy, Hammarton, Tansy, May, Sophie, Peacock, Lori, Robinson, Derrick, Robinson, Derrick R, Tetley, Laurence   +7 more
core   +3 more sources

New insights into the evolution of the Trypanosoma cruzi clade provided by a new trypanosome species tightly linked to Neotropical Pteronotus bats and related to an Australian lineage of trypanosomes

Parasites & Vectors, 2015
Bat trypanosomes are implicated in the evolution of the T. cruzi clade, which harbours most African, European and American trypanosomes from bats and other trypanosomes from African, Australian and American terrestrial mammals, including T.
Luciana Lima, Oneida Espinosa-Álvarez, C. Miguel Pinto, Manzélio Cavazzana Jr., A. Pavan, J. C. Carranza, B. Lim, M. Campaner, C. S. Takata, E. P. Camargo, P. Hamilton, M. M. Teixeira   +11 more
semanticscholar   +1 more source

Mechanisms of parasite‐mediated disruption of brain vessels

FEBS Letters, Volume 600, Issue 5, Page 591-611, March 2026.
Parasites can affect the blood vessels of the brain, often causing serious neurological problems. This review explains how different parasites interact with and disrupt these vessels, what this means for brain health, and why these processes matter. Understanding these mechanisms may help us develop better ways to prevent or treat brain infections in ...
Leonor Loira, Sílvia Arroz‐Madeira, Cláudio A. Franco, Sara Silva Pereira   +3 more
wiley   +1 more source

The haemoculture of Trypanosoma minasense chagas, 1908

Memorias do Instituto Oswaldo Cruz, 1996
Trypanosoma minasense was isolated for the first time in blood axenic culture from a naturally infected marmoset, Callithrix penicillata, from Brazil.
Mariangela Ziccardi, Ricardo Lourenço-de-Oliveira, Ricardo Nogueira   +2 more
doaj   +1 more source

Molecular Detection and Characterization of Trypanosomes Infecting Traditionally Managed Cattle in the Tropic Warm Sub-Humid Zone of Nigeria

Folia Veterinaria, 2022
Traditionally managed cattle constitutes the main source of animal protein to humans in Nigeria. However, seasonal migration in search of pasture exposes them to several vector-borne infections such as the African Animal Trypanosomosis (AAT), which ...
Kamani J., Yakubu R. A., Nnabuife H. E., Msheliza E. G., Bwala F. H., Weka P. R.   +5 more
doaj   +1 more source

The origins of a new Trypanosoma brucei rhodesiense sleeping sickness outbreak in eastern Uganda.

, 2001
BACKGROUND: Sleeping sickness, caused by two trypanosome subspecies, Trypanosoma brucei gambiense and Trypanosoma brucei rhodesiense, is a parasitic disease transmitted by the tsetse fly in sub-Saharan Africa.
Coleman, PG, Fèvre, EM, Magona, JW, Odiit, M, Welburn, SC, Woolhouse, ME   +5 more
core   +1 more source

Molecular epidemiology of African sleeping sickness [PDF]

, 2009
Human sleeping sickness in Africa, caused by Trypanosoma brucei spp. raises a number of questions. Despite the widespread distribution of the tsetse vectors and animal trypanosomiasis, human disease is only found in discrete foci which periodically give ...
A. TAIT, G. HIDE, Gibson, Hide, Mehlitz, Morrison   +5 more
core   +2 more sources

Phylogenetic and morphological characterization of trypanosomes from Brazilian armoured catfishes and leeches reveal high species diversity, mixed infections and a new fish trypanosome species

Parasites & Vectors, 2015
Several Trypanosoma species transmitted by leeches infect marine and freshwater fish worldwide. To date, all South American fish trypanosome species identified have been based on unreliable morphological parameters.
M. Lemos, B. R. Fermino, Cíntia Simas-Rodrigues, Luísa Hoffmann, Rosane Silva, E. Camargo, M. M. Teixeira, T. Souto-Padrón   +7 more
semanticscholar   +1 more source