Results 81 to 90 of about 54,903 (309)
Cytoskeleton, 2012 AbstractCytokinesis is a crucial step in the cell division cycle whereby the cell membrane and underlying cortex is remodelled and drawn together to create two new daughter cells. While in many eukaryotic systems this process is accomplished by an actomyosin contractile ring, the protozoan parasite Trypanosoma brucei displays an unusual mechanism for ...
Farr, H, Gull, K
openaire +3 more sources
Journal of Microscopy, EarlyView.Abstract Kinetoplastid parasites include several species. Trypanosoma brucei causes African sleeping sickness in humans and a wasting disease nagana in livestock. Trypanosoma cruzi is the causative agent of Chagas disease and Leishmania species cause leishmaniasis, which can present with visceral, cutaneous, or mucocutaneous symptoms.
Heidi Anderson +2 more
wiley +1 more source
Selenosugars targeting the infective stage of Trypanosoma brucei with high selectivity
International Journal for Parasitology: Drugs and Drug ResistanceEarlier evidences showed that diglycosyl diselenides are active against the infective stage of African trypanosomes (top hits IC50 0.5 and 1.5 μM) but poorly selective (selectivity index 38-folds vs. murine and human macrohages).
Estefanía Dibello +9 more
doaj +1 more source
The haemoculture of Trypanosoma minasense chagas, 1908
Memorias do Instituto Oswaldo Cruz, 1996 Trypanosoma minasense was isolated for the first time in blood axenic culture from a naturally infected marmoset, Callithrix penicillata, from Brazil.
Mariangela Ziccardi +2 more
doaj +1 more source
Molecular epidemiology of African sleeping sickness [PDF]
, 2009 Human sleeping sickness in Africa, caused by Trypanosoma brucei spp. raises a number of questions. Despite the widespread distribution of the tsetse vectors and animal trypanosomiasis, human disease is only found in discrete foci which periodically give ...
A. TAIT +5 more
core +2 more sources
The ApaH-like phosphatase TbALPH1 is the major mRNA decapping enzyme of trypanosomes
PLoS Pathogens, 2017 5’-3’ decay is the major mRNA decay pathway in many eukaryotes, including trypanosomes. After deadenylation, mRNAs are decapped by the nudix hydrolase DCP2 of the decapping complex and finally degraded by the 5’-3’ exoribonuclease. Uniquely, trypanosomes
S. Kramer
semanticscholar +1 more source
Neurobiology of Disease, 2002 Disturbances in biological rhythms pose a major disease problem, not the least in the aging population. Experimental sleeping sickness, caused by Trypanosoma brucei brucei, in rats constitutes a unique and robust chronic model for studying mechanisms of ...
G.B. Lundkvist +2 more
doaj +1 more source
Through the dark continent: African trypanosome development in the tsetse fly [PDF]
, 2013 African trypanosomes are unicellular flagellated parasites causing trypanosomiases in Africa, a group of severe diseases also known as sleeping sickness in human and nagana in cattle.
Rotureau, Brice, Van Den Abbeele, Jan
core +4 more sources
BMC Microbiology, 2018 Susceptibility of tsetse flies (Glossina spp.) to trypanosomes of both humans and animals has been associated with the presence of the endosymbiont Sodalis glossinidius. However, intrinsic biological characteristics of the flies and environmental factors
Manun Channumsin +6 more
semanticscholar +1 more source
Chemical Constituents and Biological Activities of Oxandra (Annonaceae): A Review
Chemistry &Biodiversity, Volume 23, Issue 1, January 2026.ABSTRACT Oxandra (Annonaceae) comprises 29 species distributed across South and Central America. Despite this diversity, the genus remains under‐investigated. This study presents the first comprehensive review of the chemical composition and biological activities of Oxandra species, utilizing databases such as SciFinder, ScienceDirect, PubMed, and ...
Rayssa Cota Lopes +4 more
wiley +1 more source