Results 111 to 120 of about 27,075 (226)

African trypanosomiasis [PDF]

Parasite Immunology, 2011
Morrison, L J; id_orcid 0000-0002-8304-9066, MacLeod, A   +1 more
openaire   +3 more sources

Three drug combinations for late-stage Trypanosoma brucei gambiense sleeping sickness: a randomized clinical trial in Uganda.

, 2006
OBJECTIVES: Our objective was to compare the efficacy and safety of three drug combinations for the treatment of late-stage human African trypanosomiasis caused by Trypanosoma brucei gambiense.
Louga, Albino, Fogg Carole, Louga Albino, Ghabri, S, Piola, P, Piola, Patrice, Balasegaram, M, Checchi Francesco, Balasegaram, Manica, Priotto Gerardo, Louga, A, Checchi, F, Priotto, Gerardo, Priotto, G, Erphas, Olema, Checchi, Francesco, Ghabri, Salah, Erphas, O, Balasegaram Manica, Ghabri Salah, Erphas Olema, Fogg, C, Fogg, Carole, Piola Patrice   +23 more
core   +1 more source

Early prediction of treatment efficacy in Second-Stage Gambiense Human African Trypanosomiasis

, 2012
Human African trypanosomiasis is fatal without treatment. The long post-treatment follow-up (24 months) required to assess cure complicates patient management and is a major obstacle in the development of new therapies.
Chappuis, F., Bastard, M., Laurence Flevaud, Gerardo Priotto, Etard Jean-François, Flevaud, L., Jean-François Etard, Bastard Mathieu, Etard, Jean-François, Priotto Gerardo, Etard, J-F, Priotto, Gerardo, Priotto, G, Chappuis, F, Flevaud, L, Bastard, Mathieu, François Chappuis, Mathieu Bastard, Bastard, M, Priotto, G., Flevaud Laurence, Chappuis François, Chappuis, François, Flevaud, Laurence   +23 more
core   +1 more source

Options for field diagnosis of human african trypanosomiasis.

, 2005
Human African trypanosomiasis (HAT) due to Trypanosoma brucei gambiense or T. b. rhodesiense remains highly prevalent in several rural areas of sub-Saharan Africa and is lethal if left untreated.
Chappuis, F, Loutan, L, Chappuis, F., Lejon, V., Simarro, P, Büscher, P, Loutan, L., Lejon, V, Simarro, P., Büscher, P.   +9 more
core   +1 more source

Apolipoprotein L1 (APOL1): Consideration of Molecular Evolution, Interaction with APOL3, and Impact of Splice Isoforms Advances Understanding of Cellular and Molecular Mechanisms of Cell Injury

Cells
The Apolipoprotein L1 (APOL1) innate immunity gene product represents the sole member of the APOL gene family in humans capable of secretion into circulation, thereby mediating the trypanolysis of T. brucei brucei.
Razi Khalaila, Karl Skorecki
doaj   +1 more source

Overproduction and Characterization of Recombinant Soluble Trypanosoma brucei Phospholipase A2

Engineering in Life Sciences
Trypanosoma brucei phospholipase A2 (TbPLA2) is a validated drug target but the difficulty in expressing its soluble recombinant protein has limited its exploitation for drug and vaccine development for African and American trypanosomiases.
Oluwafemi Abiodun Adepoju, Daniel Quinnell, Harshverdhan Sirohi, Emmanuel Amlabu, Abdullahi Balarabe Sallau, Abdulrazak Ibrahim, Sunday Ene‐Ojo Atawodi, Mohammed Nasiru Shuaibu, Geoffrey Chang, Emmanuel Oluwadare Balogun   +9 more
doaj   +1 more source

Trypanosomiasis [PDF]

Postgraduate Medical Journal, 1938
openaire   +2 more sources

Trypanosomiasis in Britain [PDF]

BMJ, 1965
openaire   +2 more sources

Benefit-Cost Analysis and Socio-Economic Considerations of Trypanosomiasis Control and Treatment in Northern Ghana

The paper estimates the cost of tsetse control and treatment of trypanosomiasis and the benefits involved, using benefit-cost analysis. It also estimates the extent to which socio-economic characteristics of farmers affect the use of tsetse control ...
Wahab, S., Asuming-Brempong, Samuel
core  

Trypanosomiasis in Africa [PDF]

Nature, 1949
openaire   +2 more sources