Results 101 to 110 of about 27,075 (226)

Estimates of the duration of the early and late stage of gambiense sleeping sickness

, 2008
Background: The durations of untreated stage 1 (early stage, haemo-lymphatic) and stage 2 (late stage, meningo-encephalitic) human African trypanosomiasis (sleeping sickness) due to Trypanosoma brucei gambiense are poorly quantified, but key to ...
Filipe, João AN, Haydon Daniel T, Filipe João AN, Chappuis, F., Checchi Francesco, Haydon, D.T., Checchi, F, Checchi, Francesco, Chandramohan, D, Chappuis, F, Chandramohan, Daniel, Filipe, J A N, Filipe, João A N., Haydon, Daniel T, Haydon, D T, Filipe, J.A., Haydon, Daniel T., Checchi, F., Chandramohan, D., Chappuis, François, Chappuis François, Chandramohan Daniel   +21 more
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Experimental Trypanosoma evansi infection in donkeys: hematological, biochemical and histopathological changes Infecção experimental em jumentos com Trypanosoma evansi: alterações hematológicas, bioquímicas e histopatológicas

Arquivo Brasileiro de Medicina Veterinária e Zootecnia, 2006
Five adult donkeys were experimentally infected with Brazilian strain of Trypanosoma evansi originally isolated from a naturally infected dog to study the hematological biochemical and histopathological alterations during the evolution of the disease ...
F.A. Cadioli, L.C. Marques, R.Z. Machado, A.C. Alessi, L.P.C.T. Aquino, P A. Barnabé   +5 more
doaj   +1 more source

Rearing of Glossina morsitans morsitans tsetse flies for the sterile insect technique: evaluating the impact of irradiation and transportation during early and late-stage pupal development on the quality of emerging adults

Parasite
Human African trypanosomiasis (HAT) and African animal trypanosomosis (AAT) are devastating diseases spread by tsetse flies (Glossina spp.), affecting humans and livestock, respectively.
Mirieri Caroline K., Uzel Güler Demirbas, Parker Andrew G., Bouyer Jérémy, De Vooght Linda, Ros Vera I.D., van Oers Monique M., Abd-Alla Adly M.M.   +7 more
doaj   +1 more source

Antiprotozoal Activity of Plants Used in the Management of Sleeping Sickness in Angola and Bioactivity-Guided Fractionation of Brasenia schreberi J.F.Gmel and Nymphaea lotus L. Active against T. b. rhodesiense

Molecules
Folk medicine is widely used in Angola, even for human African trypanosomiasis (sleeping sickness) in spite of the fact that the reference treatment is available for free.
Nina Vahekeni, Théo Brillatz, Marjan Rahmaty, Monica Cal, Sonja Keller-Maerki, Romina Rocchetti, Marcel Kaiser, Sibylle Sax, Kevin Mattli, Evelyn Wolfram, Laurence Marcourt, Emerson Ferreira Queiroz, Jean-Luc Wolfender, Pascal Mäser   +13 more
doaj   +1 more source

A novel allosteric inhibitor of the uridine diphosphate N-acetylglucosamine pyrophosphorylase from Trypanosoma brucei. [PDF]

, 2013
Uridine diphosphate N-acetylglucosamine pyrophosphorylase (UAP) catalyzes the final reaction in the biosynthesis of UDP-GlcNAc, an essential metabolite in many organisms including Trypanosoma brucei, the etiological agent of Human African Trypanosomiasis.
Harrison, Justin, Eskilsson, Susanne, van Aalten, Daan M. F., Collie, Iain T., Hopkins Navratilova, Iva, Ferguson, Michael A. J.; id_orcid, Navratilova, Iva Hopkins, Urbaniak, Michael D., Frearson, Julie A., Ferguson, Michael A J, Raimi, Olawale G., Aristotelous, Tonia, Urbaniak, Mick, Raimi, Olwale G., Fang, Wenxia   +14 more
core   +1 more source

The use of Multiple Displacement Amplification to increase the detection and genotyping of Trypanosoma samples immobilised on FTA filters. [PDF]

, 2007
Whole genome amplification methods are a recently developed tool for amplifying DNA from limited template. We report its application in trypanosome infections, characterized by low parasitemias.
Sweeney, L., Turner, C.M.R., Morrison, L.J., Likeufack, A.C.L., Truc, P., Tait, A., McCormack, G., MacLeod, A.   +7 more
core  

Genotypic status of the TbAT1/P2 adenosine transporter of Trypanosoma brucei gambiense isolates from northwestern Uganda following melarsoprol withdrawal [PDF]

, 2009
Human African trypanosomiasis (HAT) manifests as a chronic infection caused by <i>Trypanosoma brucei gambiense</i>, or as a more acute form due to <i>T. b. rhodesiense</i>.
Barbara Nerima, Pascal Mäser, Nerima, B., Barrett, M.P., Nerima, Barbara, de Koning Harry P., Matovu, E., Kazibwe, Anne J., Anne J N Kazibwe, Kazibwe Anne J. N., Enock Matovu, Kazibwe, A.J.N., Mäser, Pascal, De Koning, H.P., Matovu Enock, Harry P de Koning, Barrett Michael P., de Koning, Harry P., Barrett, Michael P., Michael P Barrett, Mäser, P., Mäser Pascal, Matovu, Enock, Nerima Barbara   +23 more
core   +1 more source

Combination Therapy and Phytochemical-Loaded Nanosytems for the Treatment of Neglected Tropical Diseases

Pharmaceutics
Background: Neglected tropical diseases (NTDs), including leishmaniasis, trypanosomiasis, and schistosomiasis, impose a significant public health burden, especially in developing countries.
Jacqueline Soto-Sánchez, Gilberto Garza-Treviño   +1 more
doaj   +1 more source

Eflornithine is Safer Than Melarsoprol for the Treatment of Second-Stage Trypanosoma Brucei Gambiense Human African Trypanosomiasis.

, 2005
Patients with second-stage human African trypanosomiasis treated with eflornithine (n = 251) in 2003 in Kiri, southern Sudan, had an adjusted relative risk of death of 0.2 and experienced significantly fewer cutaneous and neurological adverse effects ...
Chappuis, F, Udayraj, N, Meussen, A, Bovier, P A, Stietenroth, K   +4 more
core   +1 more source

Trypanosomiasis [PDF]

Proceedings of the Royal Society of Medicine, 1970
openaire   +4 more sources