Results 101 to 110 of about 45,242 (261)

Inhibition of Ornithine Decarboxylase 1 Mitigates Denervation‐Induced Muscle Atrophy by Suppressing Proteolysis and Preserving Muscle Stem Cell Homeostasis

Cell Proliferation, Volume 59, Issue 10, October 2026.
Polyamine metabolism is innervation responsive and involved in denervation‐induced muscle atrophy. Inhibition of polyamine metabolism attenuates muscle atrophy by restraining proteolysis and preserving MuSCs homeostasis. Denervation‐induced activation of FAP‐derived FGF7 drives premature MuSCs activation, while DFMO suppresses this paracrine cue to ...
Mingming Zhang, Feifan Chang, Siliang Ge, Fuming Cao, Pincong Fu, Haobo Zhang, Ming Chen, Yi Li, Peifu Tang, Pengbin Yin   +9 more
wiley   +1 more source

Community Health Workers' Multiple Understandings of Schistosomiasis Transmission Pathways: Exploring Contextual Factors in Côte d'Ivoire, Kenya and Uganda

Tropical Medicine &International Health, Volume 31, Issue 10, Page 1453-1464, October 2026.
ABSTRACT Objective Schistosomiasis remains a public health concern in sub‐Saharan Africa, affecting over 250 million people. In endemic settings, schistosomiasis transmission is not always understood exclusively in biomedical terms. Community health workers (CHWs) contribute to schistosomiasis control through mass drug administration and health ...
Dianne Verhoeven, Lisa Sophie Reigl, Alice Sereti Sinkeet, Mary Maghanga, Alexise Djouquou Gnahore, Bi Tra Jamal Sehi, Suzanne Lobohon Lavry, Andrea Buhl, Marie Frese, Jennifer Burrill, Eveline Hürlimann, Peter Steinmann, Nora Monnier, Ashley Preston, Janet Masaku, Matthias Richter, Mary Amuyunzu Nyamongo, Alain Toh, Stella Neema, Isabelle L. Lange, Andrea S. Winkler, on behalf of the Pediatric Praziquantel Consortium   +21 more
wiley   +1 more source

Untangling Inositol (Pyro)Phosphate Biology Through Emerging Technologies

Advanced Science, Volume 13, Issue 50, 7 September 2026.
Inositol (pyro)phosphates represent a vital class of intracellular messengers that govern multiple biological processes. The last decade has experienced a surge of interest in the functions of this class of signaling molecules, primarily due to the introduction of several innovative analytical technologies.
Adolfo Saiardi, Mengsi Lu, Yue Zhang, Anuj Shukla, An‐Li Andrea Ko, Henning J. Jessen   +5 more
wiley   +1 more source

APOL1 renal risk variants have contrasting resistance and susceptibility associations with African trypanosomiasis

eLife, 2017
Reduced susceptibility to infectious disease can increase the frequency of otherwise deleterious alleles. In populations of African ancestry, two apolipoprotein-L1 (APOL1) variants with a recessive kidney disease risk, named G1 and G2, occur at high ...
Anneli Cooper, H. Ilboudo, V. Alibu, S. Ravel, J. Enyaru, W. Weir, H. Noyes, P. Capewell, M. Camara, J. Milet, V. Jamonneau, O. Camara, E. Matovu, B. Bucheton, A. MacLeod   +14 more
semanticscholar   +1 more source

Co-Dynamics of Trypanosomiasis and Cryptosporidiosis [PDF]

, 2016
In this paper a mathematical model for trypanosomiasis-cryptosporidium co-infection dynamics is investigated to give a theoretical mathematical account of the impact of cryptosporidiosis on trypanosomiasis dynamics.
Oare Okosun, Kazeem, Mukamuri, Mirirai, Daniel Makinde, Oluwole   +2 more
core   +1 more source

Survey of Smallholder Dairy Cattle Farming System and Antibiotic Residues in Raw Cow's Milk in Bagamoyo District, Tanzania

Veterinary Medicine and Science, Volume 12, Issue 5, September 2026.
Smallholder dairy farmers in Tanzania face livestock disease challenges that drive imprudent antimicrobial use and fuel antimicrobial resistance (AMR). In Bagamoyo, poor husbandry and limited disease control result in high prevalence of vector‐borne infections, commonly treated with oxytetracycline (OTC).
Ridhiwan I. Ramadhani, Hezron Emmanuel Nonga   +1 more
wiley   +1 more source

Assessment of the Performance of Indirect Immunofluorescence Assay for Chagas Disease in Dogs Using a Reference Panel of Four Chimeric Proteins

Veterinary Medicine and Science, Volume 12, Issue 5, September 2026.
We evaluated the performance of an indirect immunofluorescence (IIF) assay for detecting anti‐Trypanosoma cruzi IgG in dogs using four chimeric IBMP antigens and latent class analysis. The IIF assay showed suboptimal sensitivity and overall accuracy compared to ELISA and LCA‐based methods.
Ângelo Antônio Oliveira Silva, Thaliane França Costa, Natália Dantas Fontes, Emily Ferreira Santos, Ana Vitória Verde Oliveira Rocha, Leandro Macedo Miranda, Fernando Almeida‐Souza, Francisco Borges Costa, Rita de Maria Seabra Nogueira, Daniel Dias Sampaio, Paola Alejandra Fiorani Celedon, Nilson Ivo Tonin Zanchin, Andréa Pereira da Costa, Fred Luciano Neves Santos   +13 more
wiley   +1 more source

Profiling Major Livestock Diseases in the East Gojjam Zone, Amhara Region, Ethiopia, Using Participatory Epidemiology Methods

Veterinary Medicine and Science, Volume 12, Issue 5, September 2026.
Participatory epidemiology identified CBPP, LSD, FMD and sheep/goat pox as the major livestock diseases in East Gojjam, Ethiopia, highlighting strong community‐based disease recognition and emphasizing the value of integrating local knowledge into veterinary surveillance and disease control systems.
Liuel Yizengaw Adnie, Haregua Yesigat, Arega Tafere, Kifle Wondimagegnehu, Dessalew Habte, Natenael Teshager, Habtamu Yalew Ayenew, Fentahun Shitaw   +7 more
wiley   +1 more source

Early prediction of treatment efficacy in Second-Stage Gambiense Human African Trypanosomiasis [PDF]

, 2012
Human African trypanosomiasis is fatal without treatment. The long post-treatment follow-up (24 months) required to assess cure complicates patient management and is a major obstacle in the development of new therapies.
Chappuis, F., Bastard, M., Laurence Flevaud, Gerardo Priotto, Etard Jean-François, Flevaud, L., Jean-François Etard, Bastard Mathieu, Etard, Jean-François, Priotto Gerardo, Etard, J-F, Priotto, Gerardo, Priotto, G, Chappuis, F, Flevaud, L, Bastard, Mathieu, François Chappuis, Mathieu Bastard, Bastard, M, Priotto, G., Flevaud Laurence, Chappuis François, Chappuis, François, Flevaud, Laurence   +23 more
core   +2 more sources

Neglected zoonotic diseases in Nigeria: role of the public health veterinarian

The Pan African Medical Journal, 2019
Zoonotic diseases accounts for about 75% of emerging infectious disease and can be devastating to both human and animal health globally. A subset of zoonotic diseases is referred to as "neglected zoonotic diseases - NZDs" as they mainly affect poor ...
Nusirat Elelu, Julius Olaniyi Aiyedun, Ibraheem Ghali Mohammed, Oladapo Oyedeji Oludairo, Ismail Ayoade Odetokun, Kaltume Mamman Mohammed, James Olaniyi Bale, Saka Nuru   +7 more
doaj   +1 more source