Results 81 to 90 of about 45,242 (261)
Epigenetic and Metabolic Changes That Drive Trained Immunity in Response to Microbes and Vaccines
Immunology, EarlyView.This graphical abstract illustrates how microbial products, vaccines and microbial metabolites activate pattern‐recognition receptor signalling, inducing metabolic rewiring and epigenetic remodelling. These changes establish long‐lasting trained immunity through the functional reprogramming of haematopoietic progenitors and innate immune cells, thereby
Desalegn Abebaw +10 more
wiley +1 more source
Update on human African trypanosomiasis (sleeping sickness)
Journal of Neurology, 2019 Human African trypanosomiasis (HAT), also known as sleeping sickness, is one of the Africa's 'neglected diseases' and is caused by infection with protozoan parasites of the Trypanosoma genus.
P. Kennedy
semanticscholar +1 more source
Stage progression and neurological symptoms in Trypanosoma brucei rhodesiense sleeping sickness: role of the CNS inflammatory response [PDF]
, 2012 Background: Human African trypanosomiasis progresses from an early (hemolymphatic) stage, through CNS invasion to the late (meningoencephalitic) stage.
MacLean, L. +19 more
core +1 more source
Journal of Agrarian Change, EarlyView.ABSTRACT This paper explores the paradox of seeking local solutions in rural development when conflicts result from structural transformations of the agrarian economy driven by national political choices. Since the 1990s, participatory approaches inspired by neo‐institutionalist theories of local governance have encouraged development actors to view ...
Toni‐Giovanni Pegurri
wiley +1 more source
African Trypanosomiasis Dynamics: Modelling the Effects of Treatment, Education, and Vector Trapping
International Journal of Mathematics and Mathematical Sciences, 2020 African trypanosomiasis is a vector-borne disease that is mainly transmitted by infected tsetse flies. A deterministic model of tsetse fly vector, human, and cattle hosts is formulated and analyzed to gain insights into the disease dynamics. The roles of
Y. Liana +3 more
semanticscholar +1 more source
Modern Agriculture, Volume 4, Issue 2, December 2026.Garlic‐derived diallyl disulfide acts as a behavioural deterrent that suppresses insect mating and oviposition through sensory pathways. The compound is detected through gustatory mechanisms involving the transient receptor potential A1 (TrpA1) channel and neural responses.
Sumit Singh, Shaoying Wu
wiley +1 more source
Current and Future Prospects of Nitro-compounds as Drugs for Trypanosomiasis and Leishmaniasis.
Current Medicinal Chemistry, 2019 Interest in nitroheterocyclic drugs for the treatment of infectious diseases has undergone a resurgence in recent years. Here we review the current status of monocyclic and bicyclic nitroheterocyclic compounds as existing or potential new treatments for ...
A. Fairlamb, Stephen Patterson
semanticscholar +1 more source
, 2023 Trypanosomatidae ailesinden protozoonlarının neden olduğu Afrika (uyku hastalığı) ve Amerika (Chagas hastalığı) trypanosomiasis hastalıkları, sırasıyla Afrika ve Latin Amerika'nın bazı bölgelerinde endemik olarak görülmektedir.
YILDIRIM, Ahmet, AKSOY. Tülay
openaire +2 more sources
Bayesian geostatistical analysis and prediction of Rhodesian human African trypanosomiasis [PDF]
, 2010 BackgroundThe persistent spread of Rhodesian human African trypanosomiasis (HAT) in Uganda in recent years has increased concerns of a potential overlap with the Gambian form of the disease.
Fevre, Eric M. +32 more
core +1 more source
Frontiers in Tropical DiseasesHuman African trypanosomiasis (HAT), commonly known as sleeping sickness, remains a significant health threat in sub-Saharan Africa. In Nigeria, the challenges of diagnosing and treating HAT are profound, especially in resource-constrained, remote areas.
Kelly Zongo, Rolayo Toyin Emmanuel
doaj +1 more source