Results 61 to 70 of about 27,075 (226)

Collateral benefits of restricted insecticide application for control of African trypanosomiasis on Theileria parva in cattle: a randomized controlled trial [PDF]

open access: yes, 2014
Tick and tsetse-borne diseases (TTBDs) constrain livestock production in tropical and subtropical regions of the world. Of this community of endemic diseases, East coast fever (T.parva) is the most important tick-borne disease (TBD) accounting for 70% of
Picozzi, Kim   +13 more
core   +1 more source

Recent Progress in the Development of Indole-Based Compounds Active against Malaria, Trypanosomiasis and Leishmaniasis

open access: yesMolecules, 2022
Human protozoan diseases represent a serious health problem worldwide, affecting mainly people in social and economic vulnerability. These diseases have attracted little investment in drug discovery, which is reflected in the limited available ...
Paulo A. F. Pacheco, Maria M. M. Santos
doaj   +1 more source

Natural History of Chronic Kidney Disease in Sickle Cell Disease

open access: yesAmerican Journal of Hematology, Volume 101, Issue 7, Page 1456-1477, July 2026.
ABSTRACT Kidney complications, referred to as nephropathy, develop early in sickle cell disease (SCD). In addition to its known morbidity, abundant data show that chronic kidney disease (CKD) is associated with an increased mortality risk in SCD. Increasing evidence suggests that the natural history of SCD nephropathy is progressive. Initial glomerular
Kenneth I. Ataga
wiley   +1 more source

Advancing diagnosis and treatment for human African trypanosomiasis in Nigeria: challenges and future directions

open access: yesFrontiers in Tropical Diseases
Human African trypanosomiasis (HAT), commonly known as sleeping sickness, remains a significant health threat in sub-Saharan Africa. In Nigeria, the challenges of diagnosing and treating HAT are profound, especially in resource-constrained, remote areas.
Kelly Zongo, Rolayo Toyin Emmanuel
doaj   +1 more source

Solid Nanomedicines of Nifurtimox and Benznidazole for the Oral Treatment of Chagas Disease

open access: yesPharmaceutics, 2022
Chagas disease (CD) is a parasitic zoonosis endemic in Central and South America affecting nearly 10 million people, with 100 million people at high risk of contracting the disease.
Miriam Rolon   +6 more
doaj   +1 more source

Synthesis, Electrochemistry, In Vitro Antiprotozoal Efficacy and Mechanistic Study of Novel ‘Ferrantoin’ and Related Derivatives

open access: yesApplied Organometallic Chemistry, Volume 40, Issue 7, July 2026.
1,2‐Disubstituted ferrocene analogues bearing hydantoin or rhodanine synthons were synthesised and assessed for antitrypanosomatid activity. An antileishmanial early lead, analogue 23, acting through ROS generation and hence oxidative stress, was uncovered.
Maryna Saayman   +7 more
wiley   +1 more source

Biological and pharmacological investigations of novel diamidines in animal models of human African trypanosomiasis [PDF]

open access: yes, 2013
"African sleeping sickness, also called human African trypanosomiasis (HAT), results from the infection of humans with either of two protozoan parasites, Trypanosoma brucei gambiense and T. b. rhodesiense. HAT is transmitted by tsetse flies (Glossina spp)
Kibuthu, John Thuita
core   +1 more source

Evaluating paratransgenesis as a potential control strategy for African trypanosomiasis. [PDF]

open access: yesPLoS Neglected Tropical Diseases, 2013
Genetic-modification strategies are currently being developed to reduce the transmission of vector-borne diseases, including African trypanosomiasis. For tsetse, the vector of African trypanosomiasis, a paratransgenic strategy is being considered: this ...
Jan Medlock   +4 more
doaj   +1 more source

Cow Milk Risk Factors Associated With Bacterial Contaminations Along Dairy Value Chain in Lushoto and Handeni Districts, Tanzania

open access: yesVeterinary Medicine and Science, Volume 12, Issue 4, July 2026.
Milk and milk products are important sources of nutrients to human and animals, but due to its physicochemical characteristics and nutritional value, it serves as an excellent medium for growth of microorganisms. Most of smallholder dairy farmers have no training on livestock husbandry and milk handling practices.
Fortunate Shija, Hezron Emmanuel Nonga
wiley   +1 more source

Home - About - Disclaimer - Privacy