Results 41 to 50 of about 43,988 (208)

Salivarian Trypanosomes Have Adopted Intricate Host-Pathogen Interaction Mechanisms That Ensure Survival in Plain Sight of the Adaptive Immune System

Pathogens, 2021
Salivarian trypanosomes are extracellular parasites affecting humans, livestock and game animals. Trypanosoma brucei rhodesiense and Trypanosoma brucei gambiense are human infective sub-species of T.
Stefan Magez, Joar Esteban Pinto Torres, Seoyeon Oh, Magdalena Radwanska   +3 more
doaj   +1 more source

Counterflow dielectrophoresis for trypanosome enrichment and detection in blood [PDF]

, 2012
Human African trypanosomiasis or sleeping sickness is a deadly disease endemic in sub-Saharan Africa, caused by single-celled protozoan parasites. Although it has been targeted for elimination by 2020, this will only be realized if diagnosis can be ...
A Carlsson, F Chappuis, FH Labeed, J Vykoukal, JA Rodriguez, KS Ralston, M Jacob, M Murray, MP Barrett, NG Green, P Gascoyne, SC Welburn, SH Holm, U Kim, WH Lumsden, WT Freeman, X-B Wang, XB Wang, Y Huang, ZK Njiru   +19 more
core   +1 more source

Design and Synthesis of Cysteine Proteases Inhibitors

Proceedings, 2019
Cysteine proteases belonging to the papain superfamily have been recognized as interesting therapeutic targets for the search for new drugs against infectious tropical diseases such as malaria (falcipain), Chagas’ disease (curtain), leishmaniasis, and ...
Florenci V. Gonzalez
doaj   +1 more source

Experiences with Diagnosis and Treatment of Chagas Disease at a United States Teaching Hospital—Clinical Features of Patients with Positive Screening Serologic Testing

Tropical Medicine and Infectious Disease, 2021
Chagas disease (CD) is the third most common parasitic infection globally and can cause cardiac and gastrointestinal complications. Around 300,000 carriers of CD live in the U.S., with about 3000 of those in Colorado.
Peter Hyson, Lilian Vargas Barahona, Laura C. Pedraza-Arévalo, Jonathan Schultz, Luisa Mestroni, Maria da Consolação Moreira, Matthew Taylor, Carlos Franco-Paredes, Esther Benamu, Poornima Ramanan, Anis Rassi, Kellie Hawkins, Andrés F. Henao-Martínez   +12 more
doaj   +1 more source

Vectors and Vector‐Borne Diseases: Biology, Epidemiology and Integrated Control Strategies

Journal of Applied Entomology, EarlyView.
ABSTRACT Vector‐Borne Diseases (VBDs), transmitted by arthropods such as mosquitoes, ticks, fleas and sandflies, represent a significant threat to global health. These diseases can be caused by a variety of pathogens, including bacteria, viruses, protozoa, and helminths.
Roberta Rinaldi, Carmen Scieuzo, Federica De Stefano, Luca Masucci, Patrizia Falabella   +4 more
wiley   +1 more source

Cinnamoyl-Oxaborole Amides: Synthesis and Their in Vitro Biological Activity

Molecules, 2018
Due to the increased interest in their application in the treatment of infectious diseases, boron-containing compounds have received a significant coverage in the literature.
Maureen Gumbo, Richard M. Beteck, Tawanda Mandizvo, Ronnett Seldon, Digby F. Warner, Heinrich C. Hoppe, Michelle Isaacs, Dustin Laming, Christina C. Tam, Luisa W. Cheng, Nicole Liu, Kirkwood M. Land, Setshaba D. Khanye   +12 more
doaj   +1 more source

4E Interacting Protein as a Potential Novel Drug Target for Nucleoside Analogues in Trypanosoma brucei

Microorganisms, 2021
Human African trypanosomiasis is a neglected parasitic disease for which the current treatment options are quite limited. Trypanosomes are not able to synthesize purines de novo and thus solely depend on purine salvage from the host environment.
Dorien Mabille, Camila Cardoso Santos, Rik Hendrickx, Mathieu Claes, Peter Takac, Christine Clayton, Sarah Hendrickx, Fabian Hulpia, Louis Maes, Serge Van Calenbergh, Guy Caljon   +10 more
doaj   +1 more source

DNA barcoding and geometric morphometry of tabanid flies (Diptera: Tabanidae) in Thailand and a new record of a Thai horse fly

Medical and Veterinary Entomology, EarlyView.
Tabanus tenens identified in this study is a newly recorded species in Thailand. DNA barcoding using the cox1 gene identified tabanid species in the present study. WGM data from different sites served as a reference for species identification. Abstract Tabanid flies are gaining high medical and veterinary importance due to their role as a vector of ...
Nantatchaporn Klaiklueng, Weluga Bootsongkorn, Patsharaporn T. Sarasombath, Pichet Ruenchit, Sirichit Wongkamchai   +4 more
wiley   +1 more source

Experimental Trypanosoma evansi infection in donkeys: hematological, biochemical and histopathological changes Infecção experimental em jumentos com Trypanosoma evansi: alterações hematológicas, bioquímicas e histopatológicas

Arquivo Brasileiro de Medicina Veterinária e Zootecnia, 2006
Five adult donkeys were experimentally infected with Brazilian strain of Trypanosoma evansi originally isolated from a naturally infected dog to study the hematological biochemical and histopathological alterations during the evolution of the disease ...
F.A. Cadioli, L.C. Marques, R.Z. Machado, A.C. Alessi, L.P.C.T. Aquino, P A. Barnabé   +5 more
doaj   +1 more source

The Contribution of Entomological Surveillance to the Control of Chagas Disease in Endemic Regions: An Integrative Literature Review

Tropical Medicine &International Health, EarlyView.
ABSTRACT Chagas disease remains a significant public health challenge in various endemic regions of Latin America. The persistence of vector‐borne transmission highlights the complexity of the issue and the limitations of traditional strategies. In this context, entomological surveillance plays a strategic and multifaceted role, not only in the early ...
Daniel Rodrigo de Lima Gomes, Gilliard do Nascimento, Pedro Mariano da Silva Rodrigues, Ana Beatriz da Silva, Ysabele Yngrydh Valente Silva, Ekarinny Myrela Brito de Medeiros, Cléber de Mesquita Andrade, Thales Allyrio Araújo de Medeiros Fernandes, José Antonio da Silva Júnior, Ellany Gurgel Cosme do Nascimento   +9 more
wiley   +1 more source