Results 41 to 50 of about 27,075 (226)
Pastoralism, 2017 This paper presents an in-depth investigation of the livelihood strategies of Fulani pastoralists in north central Nigeria. Results show a diversified crop-livestock system aimed at spreading risk and reducing cattle offtake, adapted to natural resource ...
Ayodele O. Majekodunmi +4 more
doaj +1 more source
Tropical Medicine and Infectious Disease, 2021 Chagas disease (CD) is the third most common parasitic infection globally and can cause cardiac and gastrointestinal complications. Around 300,000 carriers of CD live in the U.S., with about 3000 of those in Colorado.
Peter Hyson +12 more
doaj +1 more source
, 2023 Trypanosomatidae ailesinden protozoonlarının neden olduğu Afrika (uyku hastalığı) ve Amerika (Chagas hastalığı) trypanosomiasis hastalıkları, sırasıyla Afrika ve Latin Amerika'nın bazı bölgelerinde endemik olarak görülmektedir.
YILDIRIM, Ahmet, AKSOY. Tülay
openaire +2 more sources
Microorganisms, 2021 Human African trypanosomiasis is a neglected parasitic disease for which the current treatment options are quite limited. Trypanosomes are not able to synthesize purines de novo and thus solely depend on purine salvage from the host environment.
Dorien Mabille +10 more
doaj +1 more source
Design and Synthesis of Cysteine Proteases Inhibitors
Proceedings, 2019 Cysteine proteases belonging to the papain superfamily have been recognized as interesting therapeutic targets for the search for new drugs against infectious tropical diseases such as malaria (falcipain), Chagas’ disease (curtain), leishmaniasis, and ...
Florenci V. Gonzalez
doaj +1 more source
VIEW, EarlyView.Nanobodies, derived from the variable domains of camelid heavy‐chain‐only antibodies, have emerged as transformative biomedical tools due to their nanoscale size, exceptional stability, and unique capacity to recognize cryptic epitopes. This review provides a comprehensive overview of the field, outlining the structural and biochemical features of ...
Zhenrui Ye, Xianyang Li, Meixiao Zhan
wiley +1 more source
The natural progression of gambiense sleeping sickness: what is the evidence? [PDF]
, 2008 Gambiense human African trypanosomiasis (HAT, sleeping sickness) is widely assumed to be 100% pathogenic and fatal. However, reports to the contrary exist, and human trypano-tolerance has been postulated.
Filipe, João AN +15 more
core +1 more source
Cinnamoyl-Oxaborole Amides: Synthesis and Their in Vitro Biological Activity
Molecules, 2018 Due to the increased interest in their application in the treatment of infectious diseases, boron-containing compounds have received a significant coverage in the literature.
Maureen Gumbo +12 more
doaj +1 more source
Cell Proliferation, EarlyView.Polyamine metabolism is innervation responsive and involved in denervation‐induced muscle atrophy. Inhibition of polyamine metabolism attenuates muscle atrophy by restraining proteolysis and preserving MuSCs homeostasis. Denervation‐induced activation of FAP‐derived FGF7 drives premature MuSCs activation, while DFMO suppresses this paracrine cue to ...
Mingming Zhang +9 more
wiley +1 more source