Results 51 to 60 of about 43,988 (208)

Availability and affordability of treatment for Human African Trypanosomiasis. [PDF]

, 2001
Human African Trypanosomiasis (HAT) is a re-emerging disease whose usual treatments are becoming less efficient because of the increasing parasite resistance.
Etchegorry, M, Helenport, J, Jannin, J, Legros, D, Pecoul, B   +4 more
core   +3 more sources

Toward the elimination of HAT in Nigeria: leaving no community behind

International Journal of Infectious Diseases
Objectives: Sleeping sickness, also known as human African trypanosomiasis (HAT), is a tsetse fly-borne neglected tropical disease that affects underserved rural communities in sub-Saharan Africa.
Rolayo T. Emmanuel, Kelly Zongo, Olaleye O. Olusola   +2 more
doaj   +1 more source

Valores de transaminasas en cabras criollas infectadas con Trypanosoma vivax Transaminases values in Creole goats infected with Trypanosoma vivax

Pesquisa Agropecuária Brasileira, 2002
La presente comunicación reporta los valores de las enzimas transaminasas, Aspartatoaminotransferasa (AST) y Alaninaaminotransferasa (ALT) encontrados en sueros de cabras infectadas con la cepa de Trypanosoma vivax Stock (TvIIV) y sus controles.
Emir Espinoza, Gisela Primera
doaj   +1 more source

Exploring 6‐Hydroxy‐3‐Aryl/Heteroarylcoumarins as Promising Candidates Against Trypanosoma cruzi

ChemMedChem, Volume 21, Issue 9, 14 May 2026.
New therapies are urgently needed for Chagas disease, and screening of 6‐hydroxy‐3‐aryl/heteroarylcoumarin derivatives identified highly selective compounds with potent activity against T. cruzi. In particular, derivative 1f showed submicromolar trypomastigote potency, dual‐stage activity, and inhibition of amastigote‐to‐trypomastigote differentiation,
C. N. Pereira, L. da Silva Lara, S. da Costa Lanera, T. Pérez de Souza, M. C. de Souza Pereira, G. L. Delogu, M. Silva dos Santos, M. J. Matos   +7 more
wiley   +1 more source

Genetic and Phenotypic Features of the Five Known Polyaminopathies: A Critical Narrative Review

American Journal of Medical Genetics Part A, Volume 200, Issue 5, Page 993-1003, May 2026.
ABSTRACT Polyaminopathies are a recently described family of rare genetic neurodevelopmental disorders. Polyaminopathies disrupt the biosynthesis of the primary polyamines: putrescine, spermidine, and spermine. Snyder–Robinson syndrome results from hemizygous loss‐of‐function variants in the spermine synthase (SMS) gene, resulting in decreased or ...
Elizabeth A. VanSickle, Sara M. Sarasua, Tracy Lowe, Christopher L. Farrell, Luigi Boccuto, Charles Schwartz, Anthony E. Pegg, Angela Peron, Victor Faundes, Mythily Ganapathi, Wendy K. Chung, Alban Ziegler, Floris Hofstede, Clément Prouteau, Katharina Steindl, Colleen Olson, Orrin Devinsky, Teresa L. Mastracci, Robert A. Casero Jr., Tracy Murray Stewart, Susan Gilmour, Teri Koerner, Mary Jo Kutler, Surender Rajasekaran, Julianne Michael, André S. Bachmann, Caleb P. Bupp   +26 more
wiley   +1 more source

Detection of Trypanosoma vivax in tissues of experimentally infected goats: what is the role of adipose tissue in the life cycle of this protozoon?

Revista Brasileira de Parasitologia Veterinária, 2021
Trypanosomiasis, caused by Trypanosoma vivax, is responsible for great economic losses among livestock in Africa and South America. During the life cycle of these parasites, they may present different morphological, metabolic and physiological ...
Rosangela Zacarias Machado, Kayo José Garcia de Almeida Castilho Neto, Luiz Ricardo Gonçalves, Gisele Fabrino Machado, Maria Cecília Rui Luvizotto, Rosemeri de Oliveira Vasconcelos, Giulia Jussiani, Thiago Merighi Vieira da Silva, Lindsay Unno Gimenes, Andrew Jackson, Gavin Wright, Marta Maria Geraldes Teixeira   +11 more
doaj   +1 more source

Green fluorescent diamidines as diagnostic probes for trypanosomes [PDF]

, 2014
LED fluorescence microscopy offers potential benefits to the diagnosis of human African trypanosomiasis, as well as to other aspects of diseases management, such as detection of drug resistant strains.
Arvind Kumar, Bailey, Baker, Barrett, Bieler, Bridges, Carter, Chappuis, David W. Boykin, de Koning, Federica Giordani, Hanscheid, Jones, Keiser, Lanteri, Manoj Munde, Mathis, Mathis, Matovu, Michael P. Barrett, Minion, Mohamed A. Ismail, Paine, Steingart, Stewart, Vincent, W. David Wilson, Wilson   +27 more
core   +1 more source

Occurrence and Public Health Implications of Brucella Abortus and Antimicrobial Residues in Raw Cow Milk in Bukombe District, Tanzania

Veterinary Medicine and Science, Volume 12, Issue 3, May 2026.
Poor husbandry practices in Bukombe District accelerate diseases in livestock and indiscriminate uses of antimicrobials. Cow abortions, raw cow placenta and aborted fetuses feeding dogs, communal grazing and watering and introduction of new animals predict brucellosis in the herd.
Makoye Mhozya, Mwalimu Julius K, Hezron Emmanuel Nonga   +2 more
wiley   +1 more source

Whole-genome sequencing of trypanosoma brucei reveals introgression between subspecies that is associated with virulence [PDF]

, 2013
Human African trypanosomiasis is caused by two subspecies of Trypanosoma brucei. Trypanosoma brucei rhodesiense is found in East Africa and frequently causes acute disease, while Trypanosoma brucei gambiense is found in West Africa and is associated with
Apted, Balmer, Balmer, Berriman, Brun, Cottle, Fakhar, Gibson, Gibson, Grigg, Hertz-Fowler, Hide, Hoare, Huson, Jackson, Jamonneau, Kristjanson, Langmead, Li, Maclean, MacLeod, Masumu, Mehlitz, Morrison, Ormerod, Picozzi, Rozen, Savill, Seed, Simarro, Smith, Stevens, Thorvaldsdóttir, Truc, Tyler, Vincent   +35 more
core   +5 more sources

In Vitro Antitrypanosomal and Antibacterial Activity of Aqueous, Hydroethanolic and Ethanolic Extracts of Rumex obtusifolius L. Leaf and Root

Basic &Clinical Pharmacology &Toxicology, Volume 138, Issue 5, May 2026.
ABSTRACT Plant extracts are an important raw material for the development of new drugs. Rumex obtusifolius L., popularly known as ‘bitter dock’, has significant pharmacological properties. This study evaluated the in vitro antitrypanosomal activity of aqueous, hydroethanolic and ethanolic extracts from the leaf and roots of R. obtusifolius L.
Gabriela K. Borges, Gabriella B. Das Neves, Letícia Reichardt, Ubirajara Maciel da Costa, Luiz C. Miletti, Amanda L. Bastos‐Pereira   +5 more
wiley   +1 more source