Results 31 to 40 of about 45,242 (261)

Kynurenine pathway inhibition reduces central nervous system inflammation in a model of human African trypanosomiasis [PDF]

, 2009
Human African trypanosomiasis, or sleeping sickness, is caused by the protozoan parasites <i>Trypanosoma brucei rhodesiense</i> or <i>Trypanosoma brucei gambiense</i>, and is a major cause of systemic and neurological disability ...
Barrett, M.P., Stone, T.W., Bradley, B.M., Kennedy, P.G.E., Rodgers, J.   +4 more
core   +1 more source

Phytochemical Screening, GC-MS Analysis, and Evaluating In Vivo Antitrypanosomal Effects of a Methanolic Extract of Garcinia kola Nuts on Rats

Antibiotics, 2023
Trypanosomiasis is a serious disease that affects both humans and animals, causing social and economic losses. Efforts to find new therapeutic approaches are warranted to improve treatment options.
Fatihu Ahmad Rufa’i, Daniel Baecker, Muhammad Dauda Mukhtar   +2 more
doaj   +1 more source

Pharmacological investigations on current and new drugs for treatment of human African trypanosomiasis [PDF]

, 1999
Trypanosomiasis remains a major threat to humans in sub-Saharan Africa with 55-60 million people in 36 countries at risk of infection with T.b. gambiense or T.b. rhodesiense.
Keiser, Jennifer
core   +1 more source

Experiences of the one-health approach by the Uganda Trypanosomiasis Control Council and its secretariat in the control of zoonotic sleeping sickness in Uganda

Parasite Epidemiology and Control, 2020
Elimination of sleeping sickness from endemic countries like Uganda is key if the affected communities are to exploit the potential of the available human and livestock resources (production and productivity). Trypanosoma brucei rhodesiense, the parasite
C. Waiswa, R. Azuba, J. Makeba, I.C. Waiswa, R.M. Wangoola   +4 more
doaj   +1 more source

Recent progress in diagnosis and treatment of Human African Trypanosomiasis has made the elimination of this disease a realistic target by 2030

Frontiers in Medicine, 2022
Human African Trypanosomiasis (HAT) is caused by unicellular flagellated protozoan parasites of the genus Trypanosoma brucei. The subspecies T. b. gambiense is mainly responsible for mostly chronic anthroponotic infections in West- and Central Africa ...
Andrés Álvarez-Rodríguez, Andrés Álvarez-Rodríguez, Bo-Kyung Jin, Magdalena Radwanska, Magdalena Radwanska, Stefan Magez, Stefan Magez, Stefan Magez   +7 more
doaj   +1 more source

The use of Multiple Displacement Amplification to increase the detection and genotyping of Trypanosoma samples immobilised on FTA filters. [PDF]

, 2007
Whole genome amplification methods are a recently developed tool for amplifying DNA from limited template. We report its application in trypanosome infections, characterized by low parasitemias.
Sweeney, L., Turner, C.M.R., Morrison, L.J., Likeufack, A.C.L., Truc, P., Tait, A., McCormack, G., MacLeod, A.   +7 more
core   +5 more sources

Controlling Tsetse Flies and Ticks Using Insecticide Treatment of Cattle in Tororo District Uganda: Cost Benefit Analysis

Frontiers in Veterinary Science, 2021
Background: The endemic vector-borne diseases transmitted by tsetse and ticks impose heavy burdens on the livestock keepers in Africa. Applying deltamethrin to the belly, legs, and ears of cattle offers a possibility of mitigating these losses at a cost ...
Walter O. Okello, Walter O. Okello, Ewan T. MacLeod, Dennis Muhanguzi, Dennis Muhanguzi, Charles Waiswa, Charles Waiswa, Charles Waiswa, Susan C. Welburn, Susan C. Welburn   +9 more
doaj   +1 more source

A literature review of economic evaluations for a neglected tropical disease : human African trypanosomiasis ("sleeping sickness") [PDF]

, 2015
Human African trypanosomiasis (HAT) is a disease caused by infection with the parasite Trypanosoma brucei gambiense or T. b. rhodesiense. It is transmitted to humans via the tsetse fly.
Sutherland, C. S., Joshua Yukich, Tediosi, F., C. Simone Sutherland (689448), C Simone Sutherland, Ron Goeree (201687), Fabrizio Tediosi (247282), TEDIOSI, FABRIZIO, Ron Goeree, Goerre, R., Yukich, Joshua, Sutherland, C. Simone, Yukich, J., C. Simone Sutherl, Fabrizio Tediosi, Joshua Yukich (44606), Goeree, Ron, Yukich Joshua, Goeree Ron, Sutherland CS, Goeree R, Tediosi F., Tediosi Fabrizio, Yukich J., Yukich J, Sutherland C. S., Tediosi F, Sutherland C. Simone, Goeree R.   +28 more
core   +1 more source

Factors Affecting Sustainable Animal Trypanosomosis Control in Parts of Kaduna State, Nigeria.

Journal of Agricultural Extension, 2018
This study examined the factors affecting sustainable trypanosomiasis control in parts of Kaduna State within the sub-humid savannah ecological zone of Nigeria.  Focus group discussions were held with herdsmen and herd owners (n=85).
Hudu Okankhamame Osue
doaj   +4 more sources

Transmission concomitante de trypanosomose humaine et animale : le foyer de Mandoul au Tchad

Revue d’Elevage et de Médecine Vétérinaire des Pays Tropicaux, 2014
La trypanosomose est une maladie qui affecte à la fois l’homme et les animaux. Elle est provoquée par Trypanosoma sp. et cycliquement transmise par un vecteur, la glossine.
Peka Mallaye, L. Kohagne Tongué, N. Ndeledje, F. J. Louis, H. Mahamat Hassane   +4 more
doaj   +1 more source