Results 11 to 20 of about 45,242 (261)

The Pathogenesis of African Trypanosomiasis.

Annual Review of Pathology: Mechanisms of Disease, 2022
African trypanosomes are bloodstream protozoan parasites that infect mammals including humans, where they cause sleeping sickness. Long-lasting infection is required to favor parasite transmission between hosts.
E. Pays, M. Radwanska, S. Magez
semanticscholar   +5 more sources

Human African trypanosomiasis [PDF]

British medical journal, 2010
Epidemiology, diagnosis, and treatment of one of the world’s most neglected ...
R. Brun, J. Blum, F. Chappuis, C. Burri
semanticscholar   +2 more sources

Melarsoprol cyclodextrin inclusion complexes as promising oral candidates for the treatment of human african trypanosomiasis [PDF]

, 2011
Human African trypanosomiasis (HAT), or sleeping sickness, results from infection with the protozoan parasites Trypanosoma brucei (T.b.) gambiense or T.b.rhodesiense and is invariably fatal if untreated.
McCabe, C., Jones, A., Kennedy, P. G. E., Gibaud, S., Barrett, M. P., Rodgers, J., Bradley, B., Gettinby, G.   +7 more
core   +5 more sources

Congenital Trypanosomiasis [PDF]

Journal of Tropical Pediatrics, 2004
The last successfully treated case of congenital trypanosomiasis in Zambia was in October 1978, with detailed analysis of immunoglobulins, illustrating the waning of blood and serum levels of IgA, IgG, and IgM during treatment, up to 99 days after treatment. Twenty-five years later, we report on a case of congenital trypanosomiasis.
Mary Shilalukey, Ngoma, Mutinta, Nalubamba, Sumbukeni, Kowa, Dominic, Minyoi, Joseph, Mubanga, James, Mwansa, John, Musuku, Chifumbe, Chintu, Ganapati, Bhat, Thomas, Kapakala, Peter, Mumba, Khange, Nyalungwe   +11 more
openaire   +2 more sources

Plant Terpenoids as Hit Compounds against Trypanosomiasis

Pharmaceuticals, 2022
Human African trypanosomiasis (sleeping sickness) and American trypanosomiasis (Chagas disease) are vector-borne neglected tropical diseases, caused by the protozoan parasites Trypanosoma brucei and Trypanosoma cruzi, respectively.
R. Durão, C. Ramalhete, A. Madureira, E. Mendes, N. Duarte   +4 more
semanticscholar   +1 more source

Fast acting allosteric phosphofructokinase inhibitors block trypanosome glycolysis and cure acute African trypanosomiasis in mice

Nature Communications, 2021
The parasitic protist Trypanosoma brucei is the causative agent of Human African Trypanosomiasis, also known as sleeping sickness. The parasite enters the blood via the bite of the tsetse fly where it is wholly reliant on glycolysis for the production of
I. McNae, James Kinkead, Divya Malik, Lily Yen, Martin K. Walker, Chris Swain, S. Webster, N. Gray, P. Fernandes, E. Myburgh, E. Blackburn, Ryan Ritchie, C. Austin, Martin A. Wear, A. Highton, A. Keats, A. Vong, J. Dornan, J. Mottram, P. Michels, S. Pettit, M. Walkinshaw   +21 more
semanticscholar   +1 more source

Prévalence de la trypanosomose chez le mouton et la chèvre dans une région du Nord-Nigéria

Revue d’Elevage et de Médecine Vétérinaire des Pays Tropicaux, 1994
La prévalence de la trypanosomose a fait l'objet d'une étude menée d'avril à juin 1991 sur des moutons et des chèvres dans les régions administratives d'Alkaleri et de Gombe (Etat de Bauchi, Nord-Nigeria).
A.D. Daniel, R.A. Joshua, J.O. Kalejaiye, A.J. Dada   +3 more
doaj   +1 more source

Trypanosomiasis

Brain Pathology, 1997
African (sleeping sickness) and American (Chagas' disease) trypanosomiasis, caused by protozoa of the family Trypanosomatidae, are diseases that are endemic in parts of Africa and Latin America, respectively. Physicians in developed countries may occasionally see cases because of extensive travel and immigration from endemic countries.
L, Chimelli, F, Scaravilli
openaire   +3 more sources

Identification of sVSG117 as an immunodiagnostic antigen and evaluation of a dual-antigen lateral flow test for the diagnosis of human african trypanosomiasis [PDF]

, 2014
The diagnosis of human African trypanosomiasis (HAT) caused by Trypanosoma brucei gambiense relies mainly on the Card Agglutination Test for Trypanosomiasis (CATT). There is no immunodiagnostic for HAT caused by T. b. rhodesiense.
Sastry Lalitha, Lalitha Sastry, Lauren Sullivan, Sullivan Lauren, Ferguson, Michael A J; id_orcid, Fleming Jennifer, Steven J Wall, Sullivan, Lauren, Fleming, Jennifer, Angela Mehlert, Michael A J Ferguson, Mehlert Angela, Sastry, Lalitha, Wall, Steven J., Jennifer Fleming, Ferguson Michael A. J., Ferguson, Michael A. J., Wall, Steven J, Wall Steven J., Fleming, Jennifer R., Mehlert, Angela   +20 more
core   +2 more sources

Trypanosome Prevalence in Cattle in Lere Area in Kaduna State, North Central Nigeria

Revue d’Elevage et de Médecine Vétérinaire des Pays Tropicaux, 2004
Trypanosome prevalence in cattle was estimated in August 2001 in selected farms in the three districts of Lere local government area of Kaduna State, North Central Nigeria.
J. N. Abenga, F. N.C. Enwezor, F. A.G. Lawani, H. O. Osue, E. C.D. Ikemereh   +4 more
doaj   +1 more source