Results 91 to 100 of about 27,075 (226)

Neglected zoonotic diseases in Nigeria: role of the public health veterinarian

The Pan African Medical Journal, 2019
Zoonotic diseases accounts for about 75% of emerging infectious disease and can be devastating to both human and animal health globally. A subset of zoonotic diseases is referred to as "neglected zoonotic diseases - NZDs" as they mainly affect poor ...
Nusirat Elelu, Julius Olaniyi Aiyedun, Ibraheem Ghali Mohammed, Oladapo Oyedeji Oludairo, Ismail Ayoade Odetokun, Kaltume Mamman Mohammed, James Olaniyi Bale, Saka Nuru   +7 more
doaj   +1 more source

TNF‐α partially modulates the endothelial dysfunction during the acute phase of Trypanosoma cruzi infection

British Journal of Pharmacology, Volume 183, Issue 10, Page 2256-2272, May 2026.
Background and Purpose Whereas the effects of Trypanosoma cruzi (T. cruzi) infection are well‐characterised in the heart, its impact on the vasculature has received little attention. In this study, we investigated the effects of acute and chronic T. cruzi infection on vascular responsiveness and the underlying mechanisms.
Thales M. H. Dourado, Wanessa M. C. Awata, Gustavo F. Pimenta, Barbara M. Marchetti, Maiara V. Providello, Sérgio De Albuquerque, Carlos R. Tirapelli   +6 more
wiley   +1 more source

Computer-aided identification of Trypanosoma brucei uridine diphosphate galactose 4'-epimerase inhibitors : toward the development of novel therapies for African sleeping sickness [PDF]

, 2010
Trypanosoma brucei, the causative agent of human African trypanosomiasis, affects tens of thousands of sub-Saharan Africans. As current therapeutics are inadequate due to toxic side effects, drug resistance, and limited effectiveness, novel therapies are
Michael A. J. Ferguson, Durrant, Jacob D., Ferguson, Michael A. J., Jacob D. Durrant, Ferguson, Michael A. J.; id_orcid, Michael D. Urbaniak, McCammon, J. Andrew, Urbaniak, Michael D., J. Andrew McCammon   +8 more
core   +1 more source

Potential entry pathways for 25 vector‐borne disease agents

EFSA Journal, Volume 24, Issue 5, May 2026.
Abstract This Scientific Report identifies the potential entry pathways for 25 selected vector‐borne diseases (VBDs) into currently free EU Member States. The diseases comprise 12 listed under the Animal Health Law (AHL) and 13 non‐listed diseases, selected using predefined eligibility criteria.
European Food Safety Authority (EFSA), Sofie Dhollander, Ieva Baltusyte, Fabio Bigoni, Alessandro Broglia, Jordi Figuerola, Hans‐Hermann Thulke, Miguel Angel Chueca Miranda   +7 more
wiley   +1 more source

Trypanosoma brucei rhodesiense transmitted by a single tsetse fly bite in vervet monkeys as a model of human African trypanosomiasis [PDF]

, 2008
Sleeping sickness is caused by a species of trypanosome blood parasite that is transmitted by tsetse flies. To understand better how infection with this parasite leads to disease, we provide here the most detailed description yet of the course of ...
Thuita, J.K., John K. Thuita, Mwangangi, D., C. M. R. Turner, Matovu, E., Masiga, D., Enock Matovu, Kagira John M., John K Thuita, Kagira, J.M., John M. Kagira, David Mwangangi, Turner, C.M.R., Thuita John K., Masiga Daniel, Mwangangi David, Matovu Enock, C M R Turner, Daniel Masiga, Turner C. M. R., John M Kagira   +20 more
core   +1 more source

Transmission of human African trypanosomiasis in the Komo-Mondah focus, Gabon

The Pan African Medical Journal, 2011
BACKGROUND: Knowledge about transmission of sleeping sickness in a given focus is of a great importance since it governs the efficacy and the cost-effectiveness of control strategy.
Lisette Kohagne Tongué, Paulette Mengue M’eyi, Raceline Gounoue Kamkuimo, Dramane Kaba, Francis J Louis, Rémy Mimpfoundi   +5 more
doaj   +1 more source

Untargeted metabolomics reveals a lack of synergy between nifurtimox and eflornithine against trypanosoma brucei [PDF]

, 2012
A non-targeted metabolomics-based approach is presented that enables the study of pathways in response to drug action with the aim of defining the mode of action of trypanocides.
Burgess, K., Burchmore, Richard J S, Barrett, M.P., Creek, D.J., Vincent, I.M., Woods, Debra, Karl Burgess, Richard J S Burchmore, Woods, Debra J, Creek, Darren, Debra J. Woods (167740), Creek, Darren John, Isabel M Vincent, Vincent, Isabel M, Michael P Barrett, Darren J. Creek (167726), Woods, D.J., Isabel M. Vincent (167717), Woods Debra J., Burgess Karl, Burgess, Karl, Burchmore, Richard, Barrett, Michael P, Vincent, Isabel, Barrett Michael P., Burchmore, R.J.S., Creek Darren J., Richard J. S. Burchmore (167742), Vincent Isabel M., Darren J Creek, Karl Burgess (167732), Debra J Woods, Barrett, Michael, Michael P. Barrett (167748), Burchmore Richard J. S.   +34 more
core   +1 more source

Developing eradication investment cases for onchocerciasis, lymphatic filariasis, and human African trypanosomiasis : rationale and main challenges [PDF]

, 2013
An EIC is essentially an economic composite assessment in the broader meaning of economics, addressing thus all three fundamental economics questions. An EIC in fact answers: 1) the ‘‘What’’ question, that compares remaining in control mode versus moving
Steinmann, Peter, Marcel Tanner, Peter Steinmann, de Savigny, Don, Tediosi, Fabrizio, Fabrizio Tediosi, Don de Savigny, María Gloria Basáñez, Tanner, Marcel   +8 more
core   +1 more source

Aspectos clínicos, epidemiológicos e patológicos da infecção natural em bovinos por Trypanosoma vivax na Paraíba Clinical, epidemiological and pathological signs of natural infection in cattle by Trypanosoma vivax in Paraíba, Brazil

Pesquisa Veterinária Brasileira, 2008
Descrevem-se dois surtos de tripanossomíase por Trypanosoma vivax em bovinos, ocorridos em dois estabelecimentos do alto sertão da Paraíba. Os sinais clínicos, a patologia e a epidemiologia da doença foram estudados no período de maio de 2005 a novembro ...
Jael S. Batista, Francisco Silvestre B. Bezerra, Rodrigo A. Lira, José Ricardo G. Carvalho, Antonio M. Rosado Neto, Alinson A. Petri, Marta Maria G. Teixeira   +6 more
doaj   +1 more source

The Dispersal Ecology of Rhodesian Sleeping Sickness Following Its Introduction to a New Area [PDF]

, 2013
Tsetse-transmitted human and animal trypanosomiasis are constraints to both human and animal health in sub-Saharan Africa, and although these diseases have been known for over a century, there is little recent evidence demonstrating how the parasites ...
Eric M. Fèvre (125784), Peter M Atkinson, Wardrop, Nicola, Peter M. Atkinson (234704), Nicola A. Wardrop (234700), Fevre, Eric, Wardrop, N.A., Welburn, S.C., Atkinson, P.M, Susan C Welburn, Wardrop, Nicola A., Welburn, Susan, Eric M Fèvre, Atkinson, P, Fèvre, Eric M., Susan C. Welburn (234711), Nicola A Wardrop, Atkinson, Peter M., Welburn, Susan C., Atkinson, P.M.   +19 more
core   +1 more source