Results 121 to 130 of about 476,853 (295)

Cathepsin L and transmembrane serine protease 11E mediate trypsin-independent entry of porcine deltacoronavirus into Huh7 cells

Journal of Virology
Porcine deltacoronavirus (PDCoV) is an emerging enteric coronavirus with zoonotic potential. Previous studies showed that PDCoV productive infection is dependent on exogenous trypsin in porcine-derived cells.
Wenwen Xiao, Yuanxiang Xiong, Yuchen Wang, Ting Li, Chaoqun Chen, Yuting Shi, Guanning Su, Yanrong Zhou, Shaobo Xiao, Liurong Fang   +9 more
doaj   +1 more source

Esterified Cholesterol Conjugates Enable LNP‐Mediated mRNA Delivery to the Blood–Brain Barrier Following Intravenous Administration

Advanced Materials, EarlyView.
A cholesterol‐conjugated lipid library enabled the identification of a ligand‐free LNP platform for efficient mRNA delivery to brain endothelial cells via systemic administration. This platform achieves selective BBB targeting without disrupting barrier integrity, and enables modulation of neuroinflammation and vascular function without requiring trans‐
Zeru Tian, Xu Wang, Alexis Pacheco Benitez, Erick Guerrero, Yaou Duan, Jingwen Wei, Lukas Farbiak, Daniel J. Siegwart   +7 more
wiley   +1 more source

Upscaling the Fabrication of Rod‐Shaped Microgels: A Microfluidic Method Combining Step‐Emulsification With Consecutive Droplet Confinement in Parallelized Microchannels

Advanced Materials, EarlyView.
A microfluidic method is presented which enables parallelized fabrication of rod‐shaped microgels, based on step‐emulsification (SE) droplet generation and subsequent droplet distribution and confinement, combined in a single device. Microgel rods are fabricated in parallel at different flow rates based on two light‐mediated crosslinking chemistries ...
Matthias Mork, Ninon Möhl, Greta Romahn, Laura Klasen, Cédric Bergerbit, Laura De Laporte   +5 more
wiley   +1 more source

Ueber die Umwandlung des Trypsin-Zymogens in Trypsin

, 1904
UEBER DIE UMWANDLUNG DES TRYPSIN-ZYMOGENS IN TRYPSIN Full title: Archiv für Anatomie und Physiologie. Physiologische Abteilung, Archiv für Physiologie (-) Archiv für Physiologie (-) Ueber die Umwandlung des Trypsin-Zymogens in Trypsin (-
Hekma, E.
core   +2 more sources

A novel organic-inorganic hybrid monolith for trypsin immobilization

, 2011
A novel organic-inorganic hybrid monolith for trypsin immobilizationIn proteomics, attention has focused on various immobilized enzyme reactors (IMERs) for the realization of high throughput digestion.
Ma JunFeng, Yang KaiGuang, Liang Zhen, Zhang YuKui, Zhang LiHua, Wu ShuaiBin, Liu JinXiang, 张丽华   +7 more
core   +1 more source

Nanoporous Silica Embedded in Nanoporous Platinum: A Versatile Composite Coating for Implant‐Associated Drug Delivery From Neuronal Electrodes

Advanced Materials Technologies, EarlyView.
Nanoporous silica nanoparticles incorporated in nanoporous platinum offer the possibility for implant‐associated drug delivery from neuronal electrodes. ABSTRACT Sensorineural hearing loss, resulting from damage to the hair cells of the inner ear, profoundly impairs quality of life.
Mosaieb Habib, Tim‐Joshua Strauß, Jennifer Harre, Madeleine Goblet, Florian Klodwig‐Kirstein, Jana Schwieger, Michaela Kreienmeyer, Verena Scheper, Athanasia Warnecke, Nina Ehlert, Peter Behrens   +10 more
wiley   +1 more source

Mechanism of exogenous enzymes participation in the regulation of digestion and metabolism in model chickens

Frontiers in Veterinary Science
Experiments were performed on fistulas with duodenal cannula, which can reflect the function of the pancreas and are a model for studying digestion and metabolism when using biologically active additives.
Vladimir Vertiprakhov, Bayarma S. Dashieva, Alexei M. Grigoriev, Veronika D. Ashikhmina   +3 more
doaj   +1 more source

Trypsin and Antitrypsin [PDF]

Biochemical Journal, 1906
openaire   +2 more sources

Organic-inorganic hybrid silica monolith based immobilized trypsin reactor with high enzymatic activity

, 2008
A novel kind of immobilized trypsin reactor based on organic-inorganic hybrid silica monoliths has been developed. With the presence of cetyltrimethyl ammonium bromide (CTAB) in the polymerization mixture, the hybrid silica monolithic support was ...
Liang, Zhen, Deng, Qiliang, Qiao, Xiaoqiang, Zhang, Yukui, Zhang, Lihua, Ma, Junfeng, Tao, Dingyin, 张丽华   +7 more
core   +1 more source

Collagen‐Based Gut‐on‐Chip for In Vitro Modeling of Intestinal Barrier Function and Host‐Pathogen Interactions

Advanced Materials Technologies, EarlyView.
A collagen‐based gut‐on‐chip model replicates the intestinal extracellular matrix, supporting villi‐like structures, tight junctions, and mucin production. This biomimetic platform enables rapid epithelial differentiation and functional barrier formation.
Fernanda López García, Jacques Leng, Hugo de Oliveira, Pierre Nassoy, Karine Dementhon   +4 more
wiley   +1 more source