Results 1 to 10 of about 49,242 (209)

miR-380-3p promotes β-casein expression by targeting αS1-casein in goat mammary epithelial cells. [PDF]

Anim Biosci, 2023
Objective αS1-Casein is more closely associated with milk allergic reaction than other milk protein components. microRNA (miRNA) is a class of small non-coding RNAs that modulate multiple biological progresses by the target gene.
Song N, Luo J, Huang L, Chen X, Niu H, Zhu L.   +5 more
europepmc   +2 more sources

Bovine milk with variant β-casein types on immunological mediated intestinal changes and gut health of mice. [PDF]

Front Nutr, 2022
Dietary proteins provide bioactive peptides, which are important for host gastrointestinal functions. We hypothesized that A2-type β-casein could provide gastrointestinal benefits and improve the immune and gut health.
Liu B, Qiao W, Zhang M, Liu Y, Zhao J, Chen L.   +5 more
europepmc   +2 more sources

Worldwide Research Trends on Milk Containing Only A2 β-Casein: A Bibliometric Study. [PDF]

Animals (Basel), 2022
The protein fraction of β-casein may play a key role in the manifestation of a new intolerance: milk protein intolerance. The most common forms of β-casein among dairy cattle breeds are A1 and A2 β-casein. During gastrointestinal digestion of A1 β-casein,
Jiménez-Montenegro L, Alfonso L, Mendizabal JA, Urrutia O.   +3 more
europepmc   +2 more sources

Determination of A1 and A2 β-Casein in Milk Using Characteristic Thermolytic Peptides via Liquid Chromatography-Mass Spectrometry. [PDF]

Molecules, 2023
β-casein, a protein in milk and dairy products, has two main variant forms termed as A1 and A2. A1 β-casein may have adverse effects on humans. The fact that there is only one amino acid variation at the 67th position between A1 and A2 β-casein makes it ...
Liu Z, Pan S, Wu P, Li M, Liang D.
europepmc   +2 more sources

Transcriptomic profiling of milk fat globules in cows with different β-casein genotypes. [PDF]

Sci Rep
The A2 β-casein milk variant has attracted increasing scientific interest due to its potential health benefits. This has led to a growing trend in certain countries toward breeding A2A2 genotype cows to produce milk containing only A2 β-casein.
Jiménez-Montenegro L, Alfonso L, Soret B, Mendizabal JA, Urrutia O.   +4 more
europepmc   +2 more sources

Smoking-induced suppression of β-casein in milk is associated with an increase in miR-210-5p expression in mammary epithelia. [PDF]

Biochem Biophys Rep
Smoking during lactation harmfully affects the amount and constituents of breast milk. Infants who consume breast milk containing miR-210-5p may have a higher risk of brain-related diseases.
Chiba T, Takaguri A, Mikuma T, Kimura T, Maeda T.   +4 more
europepmc   +2 more sources

Effect of β-casein A2 cow milk supplementation on physical growth, inflammation, growth-related hormones, and nutritional biomarkers in stunted children. [PDF]

Ann Pediatr Endocrinol Metab
Purpose Previous studies have suggested that milk consumption can promote growth in children. However, limited studies have been performed on the effects of cow milk varieties, especially β-casein A2 milk.
Novika RGH, Sari AN, Nurhidayati S, Maulina R, Maulida LF, Wahidah NJ, Ilyas MF, Sumarno L, Prastowo S, Jevitt CM.   +9 more
europepmc   +2 more sources

Myotonic dystrophy-related CDC42-binding kinase alpha (MRCKα) mediates methionine- and leucine-stimulated β-casein synthesis in bovine mammary epithelial cells via targeting mTOR. [PDF]

Anim Nutr
Amino acids (AA), including methionine (Met) and leucine (Leu), stimulate milk synthesis in bovine mammary epithelial cells (BMEC) via activation of protein kinase mechanistic target of rapamycin (mTOR).
Wang F, van Baal J, Ma L, Gao X, Dijkstra J, Bu D.   +5 more
europepmc   +2 more sources

Structure of biomimetic casein micelles: Critical tests of the hydrophobic colloid and multivalent-binding models using recombinant deuterated and phosphorylated β-casein. [PDF]

J Struct Biol X
Milk contains high concentrations of amyloidogenic casein proteins and is supersaturated with respect to crystalline calcium phosphates such as apatite. Nevertheless, the mammary gland normally remains unmineralized and free of amyloid.
Raynes JK, Mata J, Wilde KL, Carver JA, Kelly SM, Holt C.   +5 more
europepmc   +2 more sources

The Function of A2β-casein and Its Application Progress in Dairy Products

Shipin gongye ke-ji, 2023
Milk is rich in many nutrients, including protein, lipids, carbohydrates, etc. Every 100 g of milk contains 3 g of protein, including mainly whey protein and casein.
Yue QIU, Xingru LU, Yu SHEN, Jinfeng GUO, Yaping ZHENG, Xinyan YANG, Yujun JIANG, Chaoxin MAN   +7 more
doaj   +1 more source