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Systematic Review of the Gastrointestinal Effects of A1 Compared with A2 β-Casein. [PDF]

Adv Nutr, 2017
Systematic review of the gastrointestinal effects of A1 compared with A2 β ...
Brooke-Taylor S, Dwyer K, Woodford K, Kost N.   +3 more
europepmc   +3 more sources

Genetic Diversity of the Beta-Casein Gene in Brown Swiss and Creole Cattle From the Peruvian Highlands. [PDF]

Anim Genet
ABSTRACT Cattle's milk and derivatives are essential for human nutrition. However, up to 90% of people experience gastrointestinal discomfort after consumption. Milk digestibility depends on its protein composition. Casein, about 80% of milk proteins, includes beta‐casein (CSN2) with two variants: A1 and A2. The A1 variant is linked to gastrointestinal
Remigio Lorenzo LR, Rivera Romero C, De Souza Pacheco J, Bueno Cabrera W, Fuentes Navarro EL, Pichler R, Periasamy K, Gutiérrez-Reynoso GA.   +7 more
europepmc   +2 more sources

Milk Containing A2 β-Casein ONLY, as a Single Meal, Causes Fewer Symptoms of Lactose Intolerance than Milk Containing A1 and A2 β-Caseins in Subjects with Lactose Maldigestion and Intolerance: A Randomized, Double-Blind, Crossover Trial. [PDF]

Nutrients, 2020
Acute-feeding and multiple-day studies have demonstrated that milk containing A2 β-casein only causes fewer symptoms of lactose intolerance (LI) than milk containing both A1 and A2 β-caseins.
Ramakrishnan M, Eaton TK, Sermet OM, Savaiano DA.   +3 more
europepmc   +2 more sources

Determination of A1 and A2 β-casein in cow milk by high-performance liquid chromatography tandem mass spectrometry

Journal of Dairy Science
: A2 β-CN milk has gained widespread acceptance due to its nutritional benefits. To verify the authenticity and detect adulteration and contamination in A2 milk, we developed an HPLC-MS/MS method for determining the characteristic peptides of A1 and A2 β-
Fengen Wang, Min Ding, Ruiju Li, Kun Wang, Xiuxin Zhao, Xia Li, Zengmei Li, Shiming Guo, Ligang Deng, Jianbin Li   +9 more
doaj   +1 more source

Comparative Effects of Milk Containing A1 versus A2 β-Casein on Health, Growth and β-Casomorphin-7 Level in Plasma of Neonatal Dairy Calves. [PDF]

Animals (Basel), 2020
Hohmann LG, Yin T, Schweizer H, Giambra IJ, König S, Scholz AM.   +5 more
europepmc   +1 more source

A2 milk - Advantages and Challenges in the Manufacturing of Dairy Products

Scientific Papers Animal Science and Biotechnologies
A2 milk is characterized by a difference in the amino acid at position 67 of the β-casein polypeptide chain, which releases much smaller amounts of bioactive opioid peptide β-casomorphin - 7 upon digestion.
Adina-Mirela Ariton, Andra-Sabina Neculai-Văleanu, Ioana Poroșnicu, Elena Ungureanu   +3 more
doaj  

Effects of Conventional Milk Versus Milk Containing Only A2 β-Casein on Digestion in Chinese Children: A Randomized Study. [PDF]

J Pediatr Gastroenterol Nutr, 2019
Sheng X, Li Z, Ni J, Yelland G.
europepmc   +1 more source

The Immunomodulatory Effects of A2 β-Casein on Immunosuppressed Mice by Regulating Immune Responses and the Gut Microbiota. [PDF]

Nutrients
Li X, Lu X, Liu M, Zhang Y, Jiang Y, Yang X, Man C.   +6 more
europepmc   +1 more source

An A2 β-casein infant formula with high sn-2 palmitate and casein phosphopeptides supports adequate growth, improved stool consistency, and bone strength in healthy, term Chinese infants: a randomized, double-blind, controlled clinical trial. [PDF]

Front Nutr
Sheng XY, Mi W, Yuan QB, Liu BY, Carnielli V, Ning YB, Einerhand AWC.   +6 more
europepmc   +1 more source