Results 151 to 160 of about 712,349 (416)
Oct4‐nanoscript, a biomimetic nanoparticle‐based artificial transcription factor, precisely regulates cellular rejuvenation by activating Oct4 target genes, restoring epigenetic marks, and reducing DNA damage. In a progeria model, it effectively rescued aging‐associated pathologies and extended lifespan.
Hongwon Kim+8 more
wiley +1 more source
Trypsin is an endoprotease commonly used for sample preparation in proteomics experiments. Importantly, protein digestion is dependent on multiple factors, including the trypsin origin and digestion conditions.
S. Walmsley+5 more
semanticscholar +1 more source
A bioengineered skin equivalent composed of electrospun poly(ε‐caprolactone) (PCL) and the bioactive peptide Fmoc‐FRGD is developed for severe burn treatment. This scaffold promotes full‐thickness skin regeneration by supporting cellular adhesion and integration. In‐vitro and in‐vivo studies show enhanced mechanical stability, accelerated wound closure,
Dana Cohen‐Gerassi+11 more
wiley +1 more source
Tryptic hydrolysis of whey protein isolate under specific incubation conditions including a relatively high enzyme:substrate (E:S) ratio of 1:10 is known to preferentially hydrolyse β-lactoglobulin (β-LG), while retaining the other major whey ...
Laura Sáez+3 more
doaj +1 more source
Antitumor factors of draining lymph node cells of the mouse sensitized with ehrlich ascites tumor cells. I. Antitumor effect of subcellular factor [PDF]
The regional lymph node cells of the mice sensitized with Ehrlich ascites tumor cells is known to possess a substance that shows antitumor activity on target cells (JTC-II cells). For the purpose to clarify the localization of this substance the regional
Nakashima, Youichi
core +1 more source
A METHOD FOR THE QUANTITATIVE DETERMINATION OF TRYPSIN AND PEPSIN [PDF]
John H. Northrop, Raymond G. Hussey
openalex +1 more source
1. If dilute solutions of purified trypsin of low salt concentration at pH from 1 to 7 are heated to 100°C. for 1 to 5 minutes and then cooled to 20°C. there is no loss of activity or formation of denatured protein. If the hot trypsin solution is added directly to cold salt solution, on the other hand, all the protein precipitates and the supernatant ...
openaire +6 more sources
High‐Throughput Microfluidic‐Mediated Assembly of Layer‐By‐Layer Nanoparticles
The layer‐by‐layer (LbL) assembly of polymer films on nanoparticle (NP) surfaces is a promising technique for targeted drug delivery. Despite its success in preclinical mouse models, a current good manufacturing practices (cGMP) compliant, clinical‐scale production method has been lacking.
Ivan S. Pires+4 more
wiley +1 more source
THE SITE OF INHIBITION OF BLOOD CLOTTING BY SOY BEAN TRYPSIN INHIBITOR 1 [PDF]
Mary Beth Glendening, Ernest W. Page
openalex +1 more source