Tumour-associated trypsin inhibitor, TATI, in patients with pancreatic cancer, pancreatitis and benign biliary diseases [PDF]
, 1986 Caj Haglund +6 more
openalex +1 more source
Zur intrinsischen Sauerstoffaffinität: die Primärstruktur eines weiteren Ruminata Hämoglobins. Methionin in βNA2 eines Stirnwaffenträgers, des Nordland-Elches (Alces alces alces). [PDF]
, 1984 Aschauer, H. +2 more
core +1 more source
USP10 Inhibits Ferroptosis via Deubiquinating POLR2A in Head and Neck Squamous Cell Carcinoma
Advanced Science, EarlyView.This study identifies USP10 as a novel deubiquitinase that antagonizes ferroptosis in head and neck squamous cell carcinoma (HNSCC). Mechanistically, USP10 directly stabilizes POLR2A protein through post‐translational deubiquitination, enabling POLR2A‐mediated transcriptional activation of SLC7A11, a key ferroptosis inhibitor.
Diekuo Zhang +13 more
wiley +1 more source
Colostral Trypsin-Inhibitor Capacity in Different Animal Species
, 1979 M. Sandholm, T. Honkanen‐Buzalski
openalex +2 more sources
Prevention of fertilization by exposure of hamster eggs to soluble acrosin [PDF]
, 1977 Fink, Edwin +3 more
core
IncRNA‐ZFAS1, an Emerging Gate‐Keeper in DNA Damage‐Dependent Transcriptional Regulation
Advanced Science, EarlyView.LncZFAS1 plays a crucial role during DNA damage response in mammalian cells. Loss of lncZFAS1 results in deficient DNA lesion removal and reduced cell viability. Mechanistically, lncZFAS1 modulates RNAPII phosphorylation and transcription and thereby promotes both GG‐NER and TC‐NER upon UV damage.
Jiena Liu +10 more
wiley +1 more source
Mesotrypsin Has Evolved Four Unique Residues to Cleave Trypsin Inhibitors as Substrates. [PDF]
J Biol Chem, 2015 Alloy AP +5 more
europepmc +1 more source
Advanced Science, EarlyView.CTSK plays a critical role in pulmonary fibrosis. Excessive CTSK accumulation interacts with SNX9 to enhance TGF‐β1‐induced SMAD3 activation and GLS1 expression in fibroblasts, driving glutamine metabolism for collagen biosynthesis and exacerbating pulmonary fibrosis.
Mengting Chen +10 more
wiley +1 more source
A soybean trypsin inhibitor. Crystallization and x-ray crystallographic study.
, 1977 David Hwang, Donald E. Foard, C. H. Wei
openalex +1 more source