Results 191 to 200 of about 5,000 (229)

Mass spectrometry of tryptamines and acetylated tryptamine derivatives

Analytical Biochemistry, 1972
Abstract Eleven mass spectra of biologically important tryptamines and their acetylated derivatives are recorded in this paper. For diagnostic purposes, the N -acetyltryptamines are preferred over other derivatives because they undergo the fewest significant rearrangements upon electron impact.
M W, Couch, C M, Williams
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Tryptamine and Serotonin Receptors

Nature, 1962
A RECENT communication by Vane et al. entitled “Tryptamine Receptors in the Central Nervous System”1 concluded, on the basis of indirect evidence, that the receptors for tryptamine and for serotonin (5-hydroxytryptamine) were the same. Because the authors neglected to mention some earlier evidence of a more direct kind which showed clearly that certain
D W, WOOLLEY, E, SHAW
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Tryptamine Metabolism in Depression

British Journal of Psychiatry, 1965
In a previous investigation we showed that large doses of DL-tryptophan (214 mg./kg. body weight) given to depressed patients receiving tranylcypromine (a monoamine oxidase inhibitor) potentiated the antidepressive effects of the drug (Coppen, Shaw and Farrell, 1963). This procedure increases the level of brain 5-hydroxytryptamine (5 HT) and tryptamine
A, Coppen, D M, Shaw, A, Malleson, E, Eccleston, G, Gundy   +4 more
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Psychoactive tryptamines from basidiomycetes

Folia Microbiologica, 2002
The review lists natural sources, i.e. strains and species of fungi producing predominantly psychoactive tryptamines (indolealkylamines), their chemical structure and properties, toxic effects on the man and psychic symptoms of intoxication. It describes the biosynthesis and production of some tryptamines by the mycelial culture of Psilocybe bohemica ...
M, Wurst, R, Kysilka, M, Flieger
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Brain levels of tryptamine

Psychopharmacologia, 1972
A modification of the method of Hess and Udenfriend (1959) for the extraction and identification of tryptamine, as well as a gas chromatographic method for identifying tryptamine, has been described. Tryptamine, using these methods, as well as thin layer chromatography, has been identified in steer, dog and human brain.
W R, Martin, J W, Sloan, S T, Christian, T H, Clements   +3 more
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Photoinduced processes in protonated tryptamine

The Journal of Chemical Physics, 2005
The electronic excited state dynamics of protonated tryptamine ions generated by an electrospray source have been studied by means of photoinduced dissociation technique on the femtosecond time scale. The result is that the initially excited state decays very quickly within 250fs.
Kang, H., Jouvet, C., Dedonder-Lardeux, C., Martrenchard, S., Charriere, C., Grégoire, G., Desfrançois, C., Schermann, J.P., Barat, M., Fayeton, J.A.   +9 more
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Benzofuran bioisosteres of hallucinogenic tryptamines

Journal of Medicinal Chemistry, 1992
The benzofuran analogues of the hallucinogens 5-methoxy-N,N-dimethyltryptamine and 5-methoxy-alpha-methyltryptamine were synthesized and evaluated for affinity at the serotonin 5-HT2 and 5-HT1A receptors in rat brain homogenate, labeled with [125I]-1-(2,5-dimethoxy-4-iodophenyl)-2-aminopropane ([125I]DOI) and [3H]-8-hydroxy-2-(N,N-di-n-propylamino ...
Z, Tomaszewski, M P, Johnson, X, Huang, D E, Nichols   +3 more
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Conformational Relaxation Paths in Tryptamine

The Journal of Physical Chemistry A, 2008
The relative fluorescence intensities of three conformers of tryptamine have been determined as a function of stagnation pressure and nozzle temperature in a supersonic expansion. The relative intensities of the conformers that are connected by different direct and indirect interconversion paths on the potential-energy hypersurface differ considerably ...
Marcel, Böhm, Robert, Brause, Christoph, Jacoby, Michael, Schmitt   +3 more
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The Ten Proaporphine-tryptamine Dimers

Journal of Natural Products, 1990
Turkish Roemeria hybrida produces ten proaporphine-tryptamine dimers, two of which, (–)-roehybridine [1] and (–)-roemeridine [8], were previously known. The dimers have been divided into three subgroups based on the stereochemistry at C-9 and at the spiro C-10 center.
Gözler B., Freyer A.J., Shamma M.
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Tryptamine in the vertebrate lens

Biochimica et Biophysica Acta (BBA) - Molecular Cell Research, 1983
Abstract The normal ionic balance and transparency of the lens is regulated by Na + −K + pumps in the lens epithelium and lens fibers. Inhibition of the (Na + +K + )-ATPase and ion transport results in osmotic swelling and opacification. We have previously shown that 10 −4 –10 −3 M tryptamine has an inhibitory effect on both ion transport and ...
O A, Candia, L J, Alvarez, P A, Lanzetta, P, Cook   +3 more
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