Results 201 to 210 of about 5,000 (229)

Tryptamines and Lysergamides

2022
Tryptamine (2-(1H-indol-3-yl)ethan-1-amine) is a naturally-occurring metabolite of the amino acid tryptophan, which, in turn, is a constituent of many proteins. Although tryptamine has few significant pharmacological properties, it forms the parent nucleus of a number of hallucinogenic drugs. Some of these tryptamines are derived from plant material or
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Catecholamines and Tryptamines

1969
Catecholamines are represented in the vertebrate nervous system most notably by noradrenaline (NA) and dopamine (DA), but also by the precursor compounds and related ones. Tryptamines are represented primarily by 5-hydroxytryptamine (5-HT or serotonin), but tryptamine itself has been detected there as well.
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N-Alkylation of phenethylamine and tryptamine

Bioorganic & Medicinal Chemistry Letters, 2005
AbstractFor Abstract see ChemInform Abstract in Full Text.
Gerta, Cami-Kobeci, Paul A, Slatford, Michael K, Whittlesey, Jonathan M J, Williams   +3 more
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Palladium-catalyzed synthesis of tryptamines and tryptamine homologues: synthesis of psilocin

Tetrahedron, 2009
A new Pd-catalyzed method for the synthesis of tryptamines is developed, and its applications to the synthesis of Corey's aspidophytine tryptamine 15 and psilocin 20 are also described.
Chunmei Hu, Hua Qin, Yuxin Cui, Yanxing Jia   +3 more
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N-methyl-α-methyl-tryptamine: A potent monoamine oxidase inhibitor and tryptamine antagonist

Biochemical Pharmacology, 1962
Abstract N-methyl-α-methyl-tryptamine is an inhibitor of monoamine oxidase (MAO) in vivo , as well as a tryptamine antagonist. At relatively low doses it enhances the effects of tryptamine by virtue of its inhibitory activity on MAO. This action is reversed at relatively high doses presumably because it competes with tryptamine for activation of ...
D H, TEDESCHI, R E, TEDESCHI, P J, FOWLER, H, GREEN, E J, FELLOWS   +4 more
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Effects of infused tryptamine in man

Psychopharmacologia, 1970
Tryptamine, infused intravenously in man, facilitates the patellar reflex, dilates pupils and elevates blood pressure. It also causes changes in vision and hearing, as well as nausea, vomiting, dizziness, sweating and heaviness of body. These changes are similar to those produced by LSD-like hallucinogens and are consistent with the hypothesis that LSD-
W R, Martin, J W, Sloan
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CNS tryptamine metabolism in hepatic coma

Journal of Neural Transmission, 1980
Lumbar CSF indoleacetic acid (IAA) was higher in patients with cirrhosis of the liver than in controls. It was also higher in CSF of patients in coma than in those with hepatic cirrhosis but not in coma. There was a strong correlation (r = 0.89, p less than 0.01) between the grade of hepatic coma and CSF IAA.
S N, Young, S, Lal
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Selective Introduction of TMS Groups in Tryptamines: Preparation of N1-TMS Derivatives of Tryptamines

Journal of Chromatographic Science, 1977
Indolethylamines (tryptamines) with a primary animofunction react with Regisil under controlled conditions to yield a mono TMS derivative. Mass spectrometry to these derivatives shows that the TMS group is substituted on the indolic nitrogen (N1) and not the primary amino nitrogen. This is confirmed by converting these compounds to their isothiocyanate
N, Narasimhachari, K, Leiner
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Cerebral Tryptamine Receptors: Functional Considerations

1968
Publisher Summary The receptors constituting the site of action of 5-HT are called tryptamine receptors. On the guinea pig ileum, excess of tryptamine abolishes the response to both tryptamine and 5-HT, and excess of 5-HT does precisely the same; both compounds appear therefore to act at the same site. In the brain, physiological effects are produced
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Tryptamines

Journal of Chromatography A, 1971
E.R. Cole, G. Crank
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