Results 171 to 180 of about 1,437,430 (390)

Cerebrospinal Fluid Metabolome in Central Nervous System Infections: A Study of Diagnostic Accuracy

Annals of Neurology, EarlyView.
Objective To assess the diagnostic accuracy of metabolites in cerebrospinal fluid (CSF) for central nervous system (CNS) infections. Methods Patients were derived from three prospective cohort studies in the Netherlands. All studies included adults suspected of a CNS infection who underwent a diagnostic lumbar puncture.
Steven L. Staal, Sabine E. Olie, Michel van Weeghel, Bauke V. Schomakers, Frédéric M. Vaz, I‐PACE Study Group, Diederik van de Beek, Matthijs C. Brouwer   +7 more
wiley   +1 more source

Effect of Pyridoxine on Tryptophan Metabolism in Rheumatoid Arthritis [PDF]

, 1962
I. M. Bett
openalex   +1 more source

Systematic Insights into the Relationship between the Microbiota–Gut–Brain Axis and Stroke with the Focus on Tryptophan Metabolism

Metabolites
Stroke, as a serious cerebral vascular disease with high incidence and high rates of disability and mortality, has limited therapeutic options due to the narrow time window.
Xinyu Shen, Xiaoqin Mu
doaj   +1 more source

Effect of treatment on the metabolism of tryptophan in childhood epilepsy. [PDF]

, 1967
Patricia A. Hughes, Bruce Bower, D. N. Raine, Nasreen A. Syed   +3 more
openalex   +1 more source

Mechanochemical Strategies Applied to the Late‐Stage Modifications of Pharmaceutically Active Compounds

Angewandte Chemie International Edition, Accepted Article.
This review explores the potential of mechanochemistry in the late‐stage modification of active pharmaceutical ingredients (APIs), offering a comprehensive analysis of methods designed to transform structurally complex molecular scaffolds. By examining the scope, efficiency, and mechanistic aspects of these approaches, the review highlights protocols ...
Johanna Templ, Lars Borchardt
wiley   +1 more source

Metabolic alterations in urine among the patients with severe fever with thrombocytopenia syndrome

Virology Journal
Background The pathogenesis of severe fever with thrombocytopenia syndrome (SFTS) remained unclear. We aimed to profile the metabolic alterations in urine of SFTS patients and provide new evidence for its pathogenesis.
Shan-Shan Zhang, Xin Yang, Wan-Xue Zhang, Yiguo Zhou, Ting-Ting Wei, Ning Cui, Juan Du, Wei Liu, Qing-Bin Lu   +8 more
doaj   +1 more source

The effect of the oral administration of leucine on the metabolism of tryptophan [PDF]

, 1963
Bhavani Belavady, S. G. Srikantia, C. Gopalan   +2 more
openalex   +1 more source

Influence of Xiaoyaosan on depressive-like behaviors in chronic stress-depressed rats through regulating tryptophan metabolism in hippocampus

Neuropsychiatric Disease and Treatment, 2018
Haiyan Jiao,1,* Zhiyi Yan,1,* Qingyu Ma,2 Xiaojuan Li,2 Youming Jiang,1 Yueyun Liu,1 Jiaxu Chen1,2 1School of Traditional Chinese Medicine, Beijing University of Chinese Medicine, Beijing 100029, China; 2Formula-Pattern Research Center, School of ...
Jiao H, Yan Z, Ma Q, Li X, Jiang Y, Liu Y, Chen J   +6 more
doaj  

Free amino acids in a cave beetle \u3cem\u3eDarlingtonea kentuckensis\u3c/em\u3e Valentine (Coleoptera: Carabidae) [PDF]

, 1974
Free amino acids of Darlingtonea kentuckensis were investigated by two-dimensional, thin-layer chromatography on Silica Gel G. Thirteen amino acids which could be identifìed (alanine, glutamic acid, glycine, histidine, isoleucine and/or leucine, lysine ...
Sperka, R. J.
core   +2 more sources

Intracellular Delivery of Native Proteins by BioReversible Arginine Modification (BioRAM) on Amino Groups

Angewandte Chemie International Edition, EarlyView.
Bioreversible Arginine Modification of amine‐containing protein residues (termed BioRAM) allows the serum‐compatible, readily accessible, and efficient delivery of native proteins into live cells. Combined with cell‐penetrating peptide (CPP) additives, BioRAM results in intracellular RNase A activity at nanomolar concentrations, thus enabling the ...
Jonathan Franke, Jan Vincent V. Arafiles, Christian Leis, Christian P. R. Hackenberger   +3 more
wiley   +1 more source