Results 191 to 200 of about 198,753 (295)

Living Microbial Drugs

open access: yesChemistry – A European Journal, EarlyView.
The introduction outlines the review scope. Microbial cell factories as living drugs cover host–gut microbiota, bacteria, yeast, and other microbial systems, with comparative host advantages. Engineering strategies include synthetic circuits, quorum sensing, and memory.
Cemile Elif Özçelik   +3 more
wiley   +1 more source

Boron Neutron Capture Therapy at a Crossroads: Translational Gap and Emerging Delivery Agents

open access: yesChemistry – A European Journal, EarlyView.
This review surveys recent advances in boron delivery agents for BNCT, emphasizing the shift from classical small molecules to multifunctional nanocarriers and theranostic systems. By integrating targeting, imaging, and therapy, next‐generation boron compounds aim to bridge the gap between (bio)chemical innovation and clinical translation.
Christoph Selg, Evamarie Hey‐Hawkins
wiley   +1 more source

It's a Gas: Bioconjugation With Vapor‐Phase Reagents

open access: yesChemistry – A European Journal, EarlyView.
Gaseous reagents are an emerging class of bioconjugation reagents that can offer alternative selectivity paradigms for the construction of precise bioconjugates. A variety of both inert and highly reactive gases have recently been developed for bioconjugation use.
Yuxuan Ding, Jun Ohata, Zachary T. Ball
wiley   +1 more source

Tryptophan metabolism reprogramming potentially contributes to the prothrombotic milieu in mice and humans with SARS-CoV-2. [PDF]

open access: yesBlood Vessel Thromb Hemost
Subramaniam S   +17 more
europepmc   +1 more source

Asymmetric Reduction of Unactivated Alkenes

open access: yesChemistry – A European Journal, EarlyView.
Unactivated alkenes rank among the most inert functional groups in synthesis and their selective reduction remains challenging. This Review charts the evolution from classical metal‐catalyzed hydrogenation to radical hydrogen atom transfer (HAT) and emerging biocatalytic concepts, highlighting how complementary mechanistic strategies, including the ...
Nico D. Fessner   +3 more
wiley   +1 more source

Enzymatic Prenylation of Proteins and Peptides: From Cysteine S‐Prenylation to Tryptophan‐Selective Biocatalysis

open access: yesChemistry – A European Journal, EarlyView.
This review highlights biocatalytic prenylation as a versatile strategy for tailoring the functional properties of peptides and proteins. By comparing branched isoprenoids with linear lipids, we illustrate how specific prenyl architectures modulate the behaviors of lipidated proteins within membrane environments.
Daisuke Fujinami   +2 more
wiley   +1 more source

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