Results 211 to 220 of about 10,379 (248)

Tryptophan metabolism in depressive illness

Psychological Medicine, 1974
SYSNOPSIS[Methylene-14C]-L-tryptophan was administered intravenously to five patients suffering from severe depression before and after clinical recovery, and to six control subjects; all subjects were tested while on a standard diet. [14C]-5-Hydroxyindoleacetic acid and [14C]-indoleacetic acid were isolated from urine during the following 48 hours and
A, Coppen, B W, Brooksbank, E, Eccleston, M, Peet, S G, White   +4 more
openaire   +2 more sources

Screening for defects in tryptophan metabolism

Journal of Chromatography A, 2000
We introduced a two-step procedure for the detection of defects in metabolism of tryptophan: (1) HPTLC (described previously) is suitable when starting the investigation, (2) two HPLC methods with isocratic elution and spectrophotometric detection are used at the next step, when pathological findings are to be confirmed and the individual metabolites ...
E, Marklová, H, Makovicková, I, Krákorová   +2 more
openaire   +2 more sources

Tryptophan metabolism in experimental porphyria

Biochemical Pharmacology, 1967
Abstract Although there seems to be no qualitative difference in the excretion of certain urinary metabolites of l -tryptophan between normal and porphyric rats, quantitative determination showed that there is a decrease in the level of excretion of l -kynurenine and 3-OH-kynurenine.
A F, Garcia, M, Grinstein
openaire   +2 more sources

Tryptophan Metabolism

Archives of Dermatology, 1967
A young girl with scleroderma and 21 members of her family were studied for their ability to metabolize tryptophan by the pathway which leads to nicotinic acid. Nine of ten female members of the family and two of 12 males had abnormal tryptophan metabolism.
openaire   +1 more source

L-tryptophan metabolism in phenylketonuria

The Journal of Pediatrics, 1966
A disturbance of the intestinal transport of L-tryptophan and L-tyrosine secondary to the high blood phenylalanine content has been suggested. The L-tryptophan metabolic abnormalities observed in untreated phenylketonuria appear to be due to a transport defect of this amino acid.
M T, Yarbro, J A, Anderson
openaire   +2 more sources

Metabolism of Tryptophan in Depressive Disease

Archives of General Psychiatry, 1973
The metabolism of tryptophan (TRYP) to kynurenine and its metabolites, to tryptamine, and through serotonin to 5-hydroxyindoleacetic acid was studied in nine depressed patients and six non-depressed psychiatric subjects. In general, there were no significant differences in the basal urinary excretion of the nine metabolites measured between the two ...
A, Frazer, G N, Pandey, J, Mendels
openaire   +2 more sources

Tryptophan Nutrition and Metabolism: An Overview

1991
Tryptophan (TRP) was the first amino acid to be recognized as being essential for normal growth of young animals when Wilcock and Hopkins (1906) and later Osborne and Mendel (1914) observed its ability to stimulate weight gain in mice and rats when added to low TRP rations. Subsequent studies in a variety of species confirmed that TRP was essential for
openaire   +2 more sources

Intermediary Metabolism of Tryptophan

Nature, 1951
C E, DALGLIESH, W E, KNOX, A, NEUBERGER
openaire   +2 more sources

TRYPTOPHAN METABOLISM IN CARCINOMA OF THE BREAST

The Lancet, 1967
Abstract The excretions of three tryptophan metabolites, 3-hydroxykynurenine, xanthurenic acid, and 3-hydroxyanthranilic acid, have been determined in the urine of 15 controls, 20 patients treated for cancer of the breast by mastectomy alone, and 24 patients treated by oophorectomy and mastectomy.
openaire   +2 more sources

Tryptophane in Carbohydrate Metabolism

Journal of Dental Research, 1947
N C, TURNER, G E, CROWELL
openaire   +2 more sources