Results 151 to 160 of about 8,037 (213)

Acute Encephalopathy in a Patient With Chronic Isotretinoin Exposure and Frequent Rizatriptan Use: A Case Report

Clinical Case Reports, Volume 14, Issue 8, August 2026.
ABSTRACT Acute encephalopathy in patients with prolonged isotretinoin exposure should prompt careful assessment of undisclosed or non‐prescribed medication use. This case suggests a possible association between high cumulative isotretinoin exposure, frequent daily rizatriptan use, and acute encephalopathy, but does not establish a definitive drug–drug ...
Soheil Roshanzamiri, Mitra Rahimi, Shahin Shadnia, Peyman Erfantalab Evini, Faraz Zandiyeh, Babak Mostafazadeh   +5 more
wiley   +1 more source

Improvement of Fibromyalgia by Immunoglobulin/Histamine Complex Therapy for Chronic Urticaria and Allergic Rhinitis: A Case Report

Clinical Case Reports, Volume 14, Issue 8, August 2026.
ABSTRACT Fibromyalgia (FM) is a chronic pain syndrome characterized by widespread musculoskeletal pain, often accompanied by fatigue, sleep disturbance, and cognitive symptoms. Although several treatment options are available, no curative therapy has been established.
Hyuk Soon Kim, Yunyoung Nam, Jeong Eun Sohn, Geunwoong Noh   +3 more
wiley   +1 more source

Atorvastatin‐Associated Severe Bradyarrhythmia Following Multiorgan Dysfunction: A Case Report

Clinical Case Reports, Volume 14, Issue 8, August 2026.
ABSTRACT Statins are the primary treatment for hypercholesterolemia and a cornerstone of atherosclerotic cardiovascular disease prevention. Although generally safe, serious adverse effects may occur in selected patients, particularly when statins are used at high doses or without medical supervision.
Xiao‐Qing Kou, Yan‐Zhen Wang, Yi‐Rong Gan, Yun‐Long Zhang, Shu‐Yun He, Zheng Zhang   +5 more
wiley   +1 more source

Secondary Adrenal Insufficiency Presenting With Severe Hyponatremia in an Elderly Patient With Primary Aldosteronism Suggesting Underlying Autonomous Cortisol Secretion

Clinical Case Reports, Volume 14, Issue 8, August 2026.
ABSTRACT Possible unrecognized cortisol autonomy in primary aldosteronism may suppress the hypothalamic–pituitary–adrenal axis. Under physiological stress, this may contribute to secondary adrenal insufficiency and severe hyponatremia. Clinicians should consider adrenal insufficiency in patients with primary aldosteronism presenting with unexplained ...
Minami Toda, Shunsuke Takahashi, Hitomi Saito, Honami Mori, Yutaka Kuroda, Akito Maeshima   +5 more
wiley   +1 more source

H Syndrome Associated With Pure Red Cell Aplasia, Rosai–Dorfman Disease, and Sensorineural Hearing Loss: Phenotypic Variability in Three Children With the Same SLC29A3 Mutation

Clinical Case Reports, Volume 14, Issue 8, August 2026.
ABSTRACT H syndrome is a rare autosomal recessive disorder caused by mutations in the SLC29A3 gene. We report three pediatric patients with a homozygous c.1309G>A (p.Gly437Arg) mutation presenting with distinct phenotypic variations. These cases expand the clinical spectrum and emphasize the importance of early genetic diagnosis and family counseling.
Mohammad Najajrah, Hadeel I. Bouzia, Nermin K. Darawi, Fatima S. Hajjaj, Nour H. Moosa, Noor M. Awad   +5 more
wiley   +1 more source

Vitamin B12 Deficiency Without Anemia Presenting With Delayed Orthostatic Hypotension in an Adolescent: A Case Report

Clinical Case Reports, Volume 14, Issue 8, August 2026.
ABSTRACT The orthostatic hypotension caused by vitamin B12 deficiency is extremely rare in young individuals. The serum vitamin B12 and anti‐intrinsic factor antibody levels of young patients with orthostatic hypotension should be evaluated regardless of the presence of anemia, and vitamin B12 administration should be promptly initiated.
Kenshin Tanaka, Shun Yamashita, Kota Minami, Yumi Harano, Masaki Tago   +4 more
wiley   +1 more source

Aceruloplasminemia Presenting With Prominent Psychiatric Symptoms and Neurodegeneration: A Case Report

Clinical Case Reports, Volume 14, Issue 8, August 2026.
ABSTRACT Aceruloplasminemia (ACP) often presents with systemic, psychiatric, and neurological features. In this case, diabetes mellitus was diagnosed several years before psychiatric symptoms, which were then followed by neurological decline, which significantly delayed diagnosis.
Ali Almarzooqi, Abdulrahman Almarzooqi, Khalifa Juma, Hamda Kamalboor   +3 more
wiley   +1 more source

Regional Functional Molecular Profiles Within the Mammalian Cortex: A Commentary on Limbic Mesocortex

Journal of Comparative Neurology, Volume 534, Issue 8, August 2026.
Two lateral mouse brain sagittal sections labeled, respectively, for Lypd1 (A) and Kcnab3 (B). (A) Lypd1 labels positively cortical Layers 2 and 5 (less heavily), but only at limbic mesocortical sites, forming the limbic ring that separates the unlabeled isocortex (IsoCx) from the unlabeled hippocampal and olfactory allocortex (Hi, Sub, ERh; OlfCx ...
Luis Puelles, Elena Garcia‐Calero
wiley   +1 more source

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The full-length TSH receptor is stabilized by TSH ligand

Journal of Molecular Graphics and Modelling, 2023
The receptor for thyroid stimulating hormone (TSHR), a GPCR, is the primary antigen in autoimmune hyperthyroidism (Graves' disease) caused by stimulating TSHR antibodies. While we have previously published a full length model of the TSHR, including its leucine rich domain (LRD), linker region (LR) and transmembrane domain (TMD), to date, only a partial
Mihaly Mezei, Rauf Latif, Terry F. Davies   +2 more
openaire   +2 more sources

IMMUNOPRECIPITATION OF TSH‐TSH RECEPTOR COMPLEXES

Clinical Endocrinology, 1985
SUMMARYThe ability of Graves' sera to interact with the TSH receptor crosslinked to a 125I‐labelled photoactive derivative of TSH has been investigated. Crosslinked complexes were prepared using non‐purified detergent solubilized human thyroid and guinea pig fat TSH receptors. Affinity purified porcine TSH receptor preparations were also used.
A B, Parkes, Y, Kajita, P R, Buckland, R D, Howells, C R, Rickards, F M, Creagh, B, Rees Smith   +6 more
openaire   +2 more sources