Levothyroxine Treatment During Pregnancy: A Metabolomics Study
ABSTRACT Levothyroxine is one of the most prescribed drugs during pregnancy. Our aim was to determine levothyroxine treatment‐associated changes in the metabolite profiles and link these to the health of the newborn. Metabolite profiles of 118 levothyroxine‐treated and 118 healthy control pregnancies were determined with nuclear magnetic resonance ...
Olli Kärkkäinen +3 more
wiley +1 more source
TSH promotes chemerin/CMKLR1-cAMP/ERK-DIO2 signaling in primary rat ependymal cells in vitro. [PDF]
Ning X +6 more
europepmc +1 more source
Intravesical therapy for recurrent urinary tract infection: a systematic review and meta‐analysis
Objective To undertake a systematic review and meta‐analysis to evaluate the efficacy, safety, and clinical applicability of intravesical instillations for preventing recurrent urinary tract infections (rUTIs). Methods PubMed/MEDLINE, Embase, Cochrane CENTRAL, Scopus, and Web of Science were searched from January 2000 to April 2025 for randomised and ...
Matthew Kwon +3 more
wiley +1 more source
Levothyroxine Intake Timing During Ramadan in Patients With Hypothyroidism: A Systematic Review and Meta-Analysis of Research Findings. [PDF]
Alzenaidi A +7 more
europepmc +1 more source
Human α7 receptors have been characterised in terms of pharmacological properties. Insertion of the N‐terminal domain of the human α7 subunit leads to honeybee and cockroach chimeric receptors activated by ACh and inhibited by α‐Bgt. Insertion of the human cys‐loop leads to cockroach chimeric receptors modulated by PNU.
Alison Cartereau +9 more
wiley +1 more source
Clinical Challenges in Transition to Adult Care for Young People With Endocrinopathies
ABSTRACT The complexity of transition of pediatric patients to adult care is well recognized, with a multidisciplinary approach widely agreed to be essential. Despite extensive existing literature in this area, practical guidance as to the management of specific medical aspects and how to address these with patients and families is lacking, with little
Margaret Zacharin, Quynh‐Nhu Nguyen
wiley +1 more source
Validation of Immunoassays for Total Thyroxine and Free Thyroxine and Age and Sex-Related Variation in Thyroid Hormone Serum Concentrations in Orangutans (Pongo sp.). [PDF]
Fayette MA +4 more
europepmc +1 more source
ABSTRACT Background Radiofrequency ablation (RFA) has become an established minimally invasive treatment for benign thyroid nodules (BTN), offering excellent safety and efficacy. However, factors predicting treatment success and post‐procedural thyroid dysfunction remain incompletely understood.
Shmuel Wechsler +3 more
wiley +1 more source
Thyroid hormone therapy in a population cohort over two decades indicates persistent overtreatment. [PDF]
Zwanziger D +5 more
europepmc +1 more source

