Results 161 to 170 of about 8,037 (213)

A Rare Cause of Discordant TSH: MACRO-TSH

Acta Endocrinologica (Bucharest), 2015
Background. When the laboratory results are not compatible with the clinical features of the patient, the presence of assay interference should be considered.
Yalcin, MEHMET MUHİTTİN, GÜLBAHAR, ÖZLEM, Altinova, ALEV, Akturk, MÜJDE YAŞIM, Ayvaz, Goksun, Ozkan, Cigdem, Arslan, Metin, Toruner, FÜSUN SAADET   +7 more
openaire   +3 more sources

TSH adenomas

Pituitary, 2006
Thyrotropin (TSH) adenomas are uncommon tumors of the anterior pituitary. Clinically, they may present with hyperthyroidism, hypothyroidism, hypopituitarism, or visual loss. Proper diagnosis requires appropriate neuroendocrine evaluation. Although transsphenoidal surgery remains the first-line treatment, adjuvant medical therapy is frequently required ...
Edward R, Laws, Mary Lee, Vance, John A, Jane   +2 more
openaire   +2 more sources

Resistance to thyrotropin (TSH) in three families is not associated with mutations in the TSH receptor or TSH.

The Journal of clinical endocrinology and metabolism, 1997
info:eu-repo/semantics ...
J. Xie, S. Pannain, J. Pohlenz, R. E. Weiss, K. Moltz, M. Morlot, C. Asteria, L. Persani, P. Beck Peccoz, J. Parma, G. Vassart, S. Refetoff   +11 more
openaire   +4 more sources

Inhibition of endogenous TSH in rats by antiserum to bovine TSH

Experientia, 1962
Gli autori hanno ottenuto in conigli un siero anti-TSH usando come antigene ormone bovino. Questo siero inibisce il TSH endogeno di ratti nutriti con dieta di Remington e trattati con tiouracile, impedendo cosi la formazione della iperplasia tiroidea.
L, BASCHIERI, M, NEGRI, F, DE LUCA, L, SERENO, L, CRAMAROSSA   +4 more
openaire   +2 more sources

Recombinant TSH-Receptor for Determination of TSH-Receptor-Antibodies

Experimental and Clinical Endocrinology & Diabetes, 2009
We have expressed the complete coding sequence of the human TSH-R in eucaryotic cells. Limiting dilution enabled us to select two clones, JP09 and JP26, which have formed the basis of binding and bioassays respectively, for TSH-R antibodies. Results obtained in the binding assay correlated well with those obtained in the TRAK (Henning Berlin) assay ...
Ludgate, Marian, Costagliola, Sabine, Danguy, Dominique, Perret, Jason, Vassart, Gilbert   +4 more
openaire   +3 more sources

Choosing Wisely^®: To TSH or not to TSH?

Journal of Hospital Medicine, 2022
Moises Auron, John Bulger
openaire   +2 more sources

TSH CROSSLINKS TO THE TSH RECEPTOR THROUGH THE β SUBUNIT

Endocrinology, 1985
TSH binds specifically to the TSH receptor present on the surface of thyroid follicular cells and consequently activates adenylate cyclase. It was not known, however, which of the two subunits of the TSH bound to the receptor. By covalently crosslinking TSH to its receptor and characterizing the product with antisera specific for either the alpha or ...
P R, Buckland, T W, Strickland, J G, Pierce, B R, Smith   +3 more
openaire   +2 more sources

Radioligand receptor assay for TSH and TSH-binding-inhibiting antibodies using solubilized TSH-receptor

Journal of Endocrinological Investigation, 1983
A radioligand receptor assay (RRA) for TSH and TSH-binding-inhibiting antibodies (TBIAb) using solubilized receptor is presented. Introducing charcoal for separation of bound and free hormone has made the assay easier to handle. The detection limit for TSH is 30 microU/ml as measured by RIA. TBIAb was found in the sera of 19 of 26 hyperthyroid patients.
P, Kotulla, C, Kostner, H, Schleusener
openaire   +2 more sources

Syndromes of resistance to TSH

Annales d'Endocrinologie, 2011
The resistance to TSH action is a genetic disease characterized by molecular defects hampering the adequate transmission of TSH stimulatory signal into thyroid cells. In principle the defect may affect every step along the cascade of events following the binding of TSH to its receptor (TSHR) on thyroid cell membranes. The phenotypic expressivity of TSH
L, Persani, G, Gelmini, F, Marelli, P, Beck-Peccoz, M, Bonomi   +4 more
openaire   +2 more sources

TSH secretion in thalassemia

Journal of Endocrinological Investigation, 1984
Thyroid function has been evaluated in 6 prepubertal male and 9 female thalassemic patients. Four of the latter were sexually immature (Group I), with very low estradiol levels and the remainder had more advanced sexual development (Group II). Subjects were challenged with TRH and the response compared to adult controls and a group of 15 males aged 13 ...
I M, Spitz, H J, Hirsch, H, Landau, E, Zylber-Haran, V, Gross, E A, Rachmilewitz   +5 more
openaire   +2 more sources