Results 11 to 20 of about 70 (65)
A case of macro-TSH consisting of IgA-bound TSH
An asymptomatic, 68-year-old Japanese man visited our hospital for further examination of subclinical hypothyroidism. At the first visit, the serum TSH level was markedly elevated (36.6 μIU/mL), but the serum level of free T4 was within the reference interval. Thyroid dysfunction due to dietary iodine excess was initially suspected. However, even after
Fukushita, Miho +8 more
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Folding-Dependent Binding of Thyrotropin (TSH) and TSH Receptor Autoantibodies to the Murine TSH Receptor Ectodomain* [PDF]
The mouse TSH receptor ectodomain (mTSHR-ecd) was amplified from murine thyroid complementary DNA and ligated into the pAcGP67B insect cell vector, and the nucleotide sequence was confirmed. Employing a baculovirus-insect cell system, the mTSHR-ecd (amino acids 22-415) was expressed as a fusion protein with the gp67 insect cell signal sequence at the ...
H, Vlase +4 more
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TSH signalling and cancer [PDF]
Thyroid cancers are the most frequent endocrine neoplasms and mutations in the thyrotropin receptor (TSHR) are unusually frequent. Here we present the state-of-the-art concerning the role of TSHR in thyroid cancer and discuss it in light of the cancer stem cell theory or the classical view.
García-Jiménez, Custodia +1 more
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The interference of anti-TSH autoantibody on clinical TSH detection
ObjectiveIt is well known that macro-thyroid-stimulating hormone (macro-TSH) could interfere with the detection of TSH. The anti-TSH autoantibody is an essential component of macro-TSH. However, the epidemiological characteristics and the clinical interference of the anti-TSH autoantibody are unclear.MethodsIn this study, the radioimmunoprecipitation ...
Mulin Tang +12 more
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STUDIES ON I131-TSH: THE INACTIVATION OF TSH BY ELEMENTAL IODINE
I131-TSH was made by the reaction of elemental iodine (I2127) and TSH preparation (Pretiron) containing 5.15% tyrosine, using radioiodine I131 as a tracer. In 1 JS of TSH preparation the amount of tyrosine was 1.83γ and 1 JS of TSH was saturated with about 2.5γ of iodine and then its activity was lost completely with iodination, but it was possible to ...
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A Study on the TSH with Phadebas TSH Test
KAISE, Kazuro +2 more
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Radioimmunoassay of TSH by TSH RIA PAC
YOSHII, Hirobumi +3 more
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Time‐dependent stabilisation of the TSH‐TSH receptor complex
Brennan, Alan +4 more
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