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Secukinumab in Moderate-to-Severe Graves Orbitopathy: A Randomized, Double-Blind, Placebo-Controlled, Multicenter Study.

J Clin Endocrinol Metab
Wolf J, Lorenz K, Othman AE, Beck A, Michel HM, Grauhan L, Elflein H, Luffy M, Eckstein A, Lahner H, Schittkowski M, Horn M, Lagrèze WA, Bleul T, Pitz S, Vorländer C, Pieterse CC, Porter B, Clemens A, Draikiwicz S, Reinhardt M, Kahaly GJ.   +21 more
europepmc   +1 more source

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TSH adenomas

Pituitary, 2006
Thyrotropin (TSH) adenomas are uncommon tumors of the anterior pituitary. Clinically, they may present with hyperthyroidism, hypothyroidism, hypopituitarism, or visual loss. Proper diagnosis requires appropriate neuroendocrine evaluation. Although transsphenoidal surgery remains the first-line treatment, adjuvant medical therapy is frequently required ...
Edward R, Laws, Mary Lee, Vance, John A, Jane   +2 more
openaire   +2 more sources

IMMUNOPRECIPITATION OF TSH‐TSH RECEPTOR COMPLEXES

Clinical Endocrinology, 1985
SUMMARYThe ability of Graves' sera to interact with the TSH receptor crosslinked to a 125I‐labelled photoactive derivative of TSH has been investigated. Crosslinked complexes were prepared using non‐purified detergent solubilized human thyroid and guinea pig fat TSH receptors. Affinity purified porcine TSH receptor preparations were also used.
A B, Parkes, Y, Kajita, P R, Buckland, R D, Howells, C R, Rickards, F M, Creagh, B, Rees Smith   +6 more
openaire   +2 more sources

A Rare Cause of Discordant TSH: MACRO-TSH

Acta Endocrinologica (Bucharest), 2015
Background. When the laboratory results are not compatible with the clinical features of the patient, the presence of assay interference should be considered.
Yalcin, MEHMET MUHİTTİN, GÜLBAHAR, ÖZLEM, Altinova, ALEV, Akturk, MÜJDE YAŞIM, Ayvaz, Goksun, Ozkan, Cigdem, Arslan, Metin, Toruner, FÜSUN SAADET   +7 more
openaire   +3 more sources

TSH Receptor Antibodies

Thyroid, 2007
The discovery of thyroid-stimulating autoantibodies by Adams and Purves 50 years ago was one of the most important observations in the history of thyroidology. Since that time, the thyroid-stimulating hormone receptor (TSHR) has been shown to be the antigen recognized by these autoantibodies (1974) and the receptor cloned (1989).
Bernard Rees, Smith, Jane, Sanders, Jadwiga, Furmaniak   +2 more
openaire   +2 more sources