Results 61 to 70 of about 79,280 (262)

Subclinical cardiac alterations and cardiometabolic profile in adolescents with newly diagnosed polycystic ovary syndrome: A cross‐sectional comparative echocardiographic study

open access: yesInternational Journal of Gynecology &Obstetrics, EarlyView.
Abstract Objective While cardiometabolic comorbidities have been well established in adults with polycystic ovary syndrome (PCOS), it remains unclear whether the early signs of cardiovascular morbidity emerge during adolescence. This study aimed to investigate whether metabolic and cardiovascular alterations begin in adolescents with PCOS.
Demet Aygün Ari   +8 more
wiley   +1 more source

Assessment of Thyroid Uptake Ratio Values in a Normal Population. Establishment of Normal Reference Values for 99mTc‐Pertechnetate Thyroid Uptake in an Australian Population

open access: yesJournal of Medical Radiation Sciences, EarlyView.
An Australian first, this study examined normal reference ranges for 99mTc‐pertechnetate thyroid uptake. Through a retrospective and prospective analysis, this study found a new reference range of 0.4%–2.4%. The findings suggest that locally derived reference values may differ from historical data and highlight the importance of region‐specific ...
Bethany Wornes   +2 more
wiley   +1 more source

Proteomics‐Based Identification of the Pyroptosis‐Related Biomarker PCSK9 and Its Association With the Pathogenesis of Rheumatoid Arthritis

open access: yesThe Kaohsiung Journal of Medical Sciences, EarlyView.
ABSTRACT Rheumatoid arthritis (RA) is a common autoimmune disease, and early diagnosis is critical for effective treatment. This study aims to identify potential biomarkers related to pyroptosis through serum proteomics analysis, offering new insights for the early diagnosis of RA.
Lei Wang   +10 more
wiley   +1 more source

Correlations Among Glycemia and Glucose Variability, Thyroid Hormones, and Albuminuria in Patients With Type 2 Diabetes Mellitus

open access: yesThe Kaohsiung Journal of Medical Sciences, EarlyView.
ABSTRACT Hyperglycemia, glucose fluctuations, and thyroid dysfunction contribute to the progression of diabetic nephropathy. This study aimed to investigate the associations of glycemia, glucose variability, and thyroid hormones with albuminuria in patients with type 2 diabetes mellitus (T2DM). In total, 451 T2DM patients were included.
Na Luo   +12 more
wiley   +1 more source

Standardization of TSH and FT4 to gestational age in early pregnancy and associations with clinical outcomes

open access: yesEuropean Thyroid Journal
Background: To account for pregnancy-specific changes in thyroid physiology, international guidelines recommend the use of trimester-specific reference intervals.
Joris A J Osinga   +7 more
doaj   +1 more source

Possible Consequences of Changing of the TSH Reference Ranges

open access: yesКлиническая и экспериментальная тиреоидология, 2009
We retrospectively analyzed the results of measurements of serum TSH and free T4 concentrations performed in1014 patients hospitalised in Federal Endocrinological Research Center without known thyroid disorders.

doaj   +1 more source

Bilateral Ophthalmoplegia After Neoadjuvant Pembrolizumab for Oral Cavity Squamous Cell Carcinoma

open access: yesThe Laryngoscope, EarlyView.
The role of immune checkpoint inhibition (ICI) therapy in the treatment of head and neck squamous cell carcinoma (HNSCC) is expanding with increased utilization of neoadjuvant and adjuvant pembrolizumab in the setting of locally advanced disease. This report describes the presentation and management of the first known case of pembrolizumab‐induced ...
Leonard E. Estephan   +3 more
wiley   +1 more source

Circadian rhythm of TSH secretion during TSH-suppression therapy

open access: yesКлиническая и экспериментальная тиреоидология, 2011
Тo investigate circadian rhythm of TSH secretion during TSH-suppression therapy. 17 patients taking TSH-suppression therapy, at the age of 18–60 years have been included.

doaj   +1 more source

Mass Spectrometry Insights Into Post‐Translational Modifications in Extracellular Vesicles

open access: yesMass Spectrometry Reviews, EarlyView.
ABSTRACT Extracellular vesicles (EVs) are membrane‐enclosed structures secreted by virtually all living cells, serving as essential mediators of intercellular communication in both physiological and pathological processes. There is growing interest in their potential applications as biomarkers, therapeutic targets, and drug delivery systems, which ...
Dávid Virág   +5 more
wiley   +1 more source

Musculoskeletal Outcomes of Glucagon‐Like Peptide‐1 Receptor Agonists Versus Other Antiobesity Agents in Nondiabetic Adults

open access: yesObesity, EarlyView.
ABSTRACT Objective This study aimed to evaluate the association of glucagon‐like peptide‐1 receptor agonists (GLP‐1 RAs) with risks of osteoporosis, major osteoporotic fractures, and degenerative musculoskeletal disorders in nondiabetic adults with obesity compared with other obesity medications.
Jie‐Syuan Wu   +5 more
wiley   +1 more source

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